Dendritic cells (DCs) are the Generals of the immune system and
instruct the immune system on how to clear infectious
micro-organims. DCs ingest these microbes, then travel to the
headquarters of the immune system where they instruct soldier T
cells. This leads to the killing of infected cells and the release
of antibodies to neutralize remaining and future microbes. In
recent years, it has become clear that there are different family
members, or subtypes, of DCs - akin to having different Generals
for the army, navy and air force. Each subtype has a specialized
function in the detection of different types of microbes and their
subsequent clearance. What has puzzled scientists is how these
subtypes derive from white blood cell progenitors and stem cells in
a process known as haematopoiesis. This thesis delves into the
isolation and characterization of the progenitors of the DC
subtypes under normal conditions and after inflammation, and
uniquely addresses this complexity at the single cell level. This
groundbreaking work created a paradigm shift in how we think of DCs
and their development within the haematopoietic tree.
General
| Imprint: |
Lap Lambert Academic Publishing
|
| Country of origin: |
Germany |
| Release date: |
October 2009 |
| First published: |
October 2009 |
| Authors: |
Shalin H. Naik
|
| Dimensions: |
229 x 152 x 12mm (L x W x T) |
| Format: |
Paperback - Trade
|
| Pages: |
212 |
| ISBN-13: |
978-3-8383-1836-3 |
| Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
General
|
| LSN: |
3-8383-1836-6 |
| Barcode: |
9783838318363 |
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
(11)
