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Phosphodiesterases as Drug Targets (Paperback, 2011 ed.) Loot Price: R7,700
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Phosphodiesterases as Drug Targets (Paperback, 2011 ed.): Sharron H. Francis, Marco Conti, Miles D. Houslay

Phosphodiesterases as Drug Targets (Paperback, 2011 ed.)

Sharron H. Francis, Marco Conti, Miles D. Houslay

Series: Handbook of Experimental Pharmacology, 204

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Loot Price R7,700 Discovery Miles 77 000 | Repayment Terms: R722 pm x 12*

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Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Handbook of Experimental Pharmacology, 204
Release date: November 2013
First published: 2011
Editors: Sharron H. Francis • Marco Conti • Miles D. Houslay
Dimensions: 235 x 155 x 28mm (L x W x T)
Format: Paperback
Pages: 522
Edition: 2011 ed.
ISBN-13: 978-3-642-26945-5
Categories: Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
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LSN: 3-642-26945-1
Barcode: 9783642269455

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