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Recent Progress in Failing Heart Syndrome (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R1,554
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Recent Progress in Failing Heart Syndrome (Paperback, Softcover reprint of the original 1st ed. 1991)
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Heart failure is a syndrome caused by a heart dysfunction that
leads to insuf ficient blood in the peripheral tissues for their
metabolic demands. This syn drome still remains an obscure clinical
entity and even its definition is disputed. It has become
increasingly apparent that heart failure may relate not only to
cardiac dysfunction but also to other physiological alterations
involved in the maintenance of circulatory homeostasis. In 1988,
the Japanese Circulation Society organized a three-year project for
research on heart failure. The research group consisted of ten
investigators, all relatively young but well recognized
internationally for their research accomplishments. This book
represents a compilation of the achievements by this group during
the past three years which have led to new insights into the
pathophysiologic mechanisms of heart failure, and diagnosis,
evaluation and treatment of this syndrome. Contents include
research into the cellular biology of congestive heart failure, and
a framework of pressure-volume relationships enabling assessment of
ventricular contraction energetics or coupling of ventricular
properties and arterial load. This conceptual framework is of vital
significance, particularly when we consider the failing heart as an
energy-depleted state. An understanding of the neuroendocrine
responses to explain the pathophy siology of congestive heart
failure is perhaps the most important advance, and has led to new
developments in therapy. This book also includes an analysis of
mechanical factors, including both regional, and global ventricular
functions, and this is related to the under standing of the
pathophysiology of congestive heart failure."
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