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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Cancer Metastasis Through the Lymphovascular System (Hardcover, 1st ed. 2022)
Loot Price: R4,087
Discovery Miles 40 870
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Cancer Metastasis Through the Lymphovascular System (Hardcover, 1st ed. 2022)
Expected to ship within 12 - 17 working days
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This textbook describes in detail the process of cancer metastasis
from a single cell in the primary site through its arduous journey
to the sentinel lymph node as the main gateway and beyond to
distant sites. The most up-to-date knowledge on key topics in the
molecular biology, diagnosis, and treatment of metastatic cancer is
highlighted by a large panel of experts. The book begins with a
comprehensive overview of the genetic and molecular mechanisms that
promote or inhibit cancer metastasis through lymphatic pathways to
lymph nodes or through vascular pathways to distant sites,
providing the reader with an essential basic knowledge. This is
followed by further details on the role of the immune system within
the primary tumor and the lymph node and the importance of the
microenvironment at the metastatic site. The role of the sentinel
lymph node in cancer metastasis is emphasized. Special attention is
also given to state-of-the-art imaging techniques for the detection
of early-stage cancer and cancer metastases, as well as the use of
liquid biopsies in sarcoma, prostate, gastrointestinal, and lung
cancer. Clinical patterns of malignant tumors arising in different
organ systems are compared, described, and discussed with the goal
of determining what similarities and/or differences exist. The book
concludes with a detailed discussion of surgical intervention,
radiation, and systemic therapy of primary and metastatic cancer,
and briefly previews several emerging topics, such as the latest
findings on personalized cancer therapy, cancer stem cells, unique
molecular mechanisms of virus-induced cancer, the impact of the
microbiome on cancer metastasis and the application of artificial
intelligence in cancer metastasis research. By providing
fundamental knowledge of the biological and clinical aspects of
cancer metastasis, this book will be an important reference for
cancer researchers, clinical oncologists, teachers, and students.
Written by experts in the field, each chapter includes a summary of
the chapter's key points and open-ended questions that address
pressing issues in the field and encourage the reader to consider
future directions.
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