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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases
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Inflammasome Signaling and Bacterial Infections (Hardcover, 1st ed. 2016)
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Inflammasome Signaling and Bacterial Infections (Hardcover, 1st ed. 2016)
Series: Current Topics in Microbiology and Immunology, 397
Expected to ship within 10 - 15 working days
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This volume details our current understanding of the architecture
and signaling capabilities of known canonical and non-canonical
inflammasome complexes and highlights their action, in particular
in response to infection with important bacterial model organisms
and the corresponding disease pathologies. The first chapters
review new insights into the assembly and structures of
inflammasome components and emphasize general strategies of up- and
downstream signaling events. In addition, the authors specifically
discuss the composition and activity of inflammasomes during
infection with various gut pathogens (Salmonella, Shigella,
Yersinia, Listeria and Helicobacter), respiratory pathogens
(Mycobacterium, Legionella, Burkholderia and Streptococcus) as well
as skin and soft tissue pathogens (Francisella and Staphylococcus).
The discoveries presented provide a better understanding of the
cellular and molecular biology of inflammasomes, which will
pinpoint important new therapeutic targets for the treatment and
prevention of multiple infectious diseases in the future. It is a
valuable resource for students, scientists and clinicians,
providing up-to-date information on this emerging research topic.
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