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T-type Calcium Channels in Basic and Clinical Science (Hardcover, 2015 ed.)
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T-type Calcium Channels in Basic and Clinical Science (Hardcover, 2015 ed.)
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T-type calcium channels are prevalent in every organ of the body,
and are believed to play a part in a variety of physiological
processes, including contraction, shape change, secretion, endo-
and exocytosis, cell proliferation and differentiation, modulation
of enzyme function, and cell cycle progression. As such, research
on the roles of these channels in a wide range of diseases has
attracted increasing attention in recent years. The purpose of this
book is to present a series of unique and comprehensive reviews of
our current understanding of T-type calcium channels at the level
of the basic sciences as well as the clinical sciences. For key
organ systems, information is provided on the correlation between
the molecular, biophysical and pharmacological properties of the
channels, their cellular mechanisms, and their potential roles in
the pathogenesis of various diseases. The compilation presents both
commonplace and less well-known findings on these channels in a
format designed to appeal to both casual readers and specialists in
basic and clinical research on these transporters.
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