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The Coxsackie B Viruses (Paperback, Softcover reprint of the original 1st ed. 1997)
Loot Price: R2,956
Discovery Miles 29 560
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The Coxsackie B Viruses (Paperback, Softcover reprint of the original 1st ed. 1997)
Series: Current Topics in Microbiology and Immunology, 223
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S. TRACY Late in the 1940s, a virus was isolated from a young
patient with a flaccid par alysis in the sleepy Hudson River town
of Coxsackie in the state of New York. Within the next few years,
it was apparent that this and other similar viruses were not
polioviruses but were indeed a new group of viruses, viruses that
by the mid- 1950s had been found to be commonly associated with
pediatric inflammatory heart disease. Two groups of
coxsackieviruses (A and B) were differentiated on the basis of the
type of paralysis induced in suckling mice by these viruses. Group
B coxsackieviruses, because of their primacy as etiologic agents of
human acute viral myocarditis and its relatively common sequela,
dilated cardiomyopathy, are the focus of this volume. of the
century approaches, the massive international effort to eradi As
the end cate polioviruses through vaccination as causes of human
disease has been success ful in the Western Hemisphere and in many
parts of Europe, and it is expected that worldwide eradication may
be achieved within the near future. While this is wonderful news,
there are sadly no similar efforts being planned to combat the
numerous other human enteroviruses that daily incur widespread
morbidity and mortality throughout the world. While this is due in
part to the lack of specific know ledge about the other human
enteroviruses, it is also due to the perceptions of industry that
there is insufficient profit to be made by developing these
vaccines.
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