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Stem Cells and Aging (Paperback)
Loot Price: R2,935
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Stem Cells and Aging (Paperback)
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Stem Cells and Aging covers what is known about the effect of time
and age on the basic units of life, which are the corresponding
tissue-specific or adult stem cells. Even though the concept of
stem cells was introduced nearly a century ago by Alexander
Maximow, modern stem-cell research began in 1963 when James Till,
Ernest McCullough and Lou Siminovitch established assays to detect
hematopoietic stem cells. In fact, given the importance of the
aging-associated diseases, scientists have developed a keen
interest in understanding the aging process as they attempt to
define the role of dysfunctional stem cells in the aging process.
With an aging population worldwide, understanding these age-related
stem cell changes at a basic biology level and at the level of
their influences for regenerative medicine is of interest and
importance. There is increasing evidence that the aging process can
have much adverse effects on stem cells. In the modern era, one of
the emerging fields in treating human diseases is stem cell
research, as stem cells have the remarkable potential to treat a
wide range of diseases. Nevertheless, understanding the molecular
mechanism involved in aging and deterioration of stem cell function
is crucial in developing effective new therapies for aging.
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