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Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 (Paperback, Softcover reprint of the original 1st ed. 2015)
Loot Price: R3,506
Discovery Miles 35 060
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Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 (Paperback, Softcover reprint of the original 1st ed. 2015)
Series: Fungal Biology
Expected to ship within 10 - 15 working days
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Fungi produce many chemically diverse secondary metabolites whose
biological roles largely remain elusive. Within the increasing
number of sequenced fungal genomes several important genes involved
in secondary metabolite formation have been identified. Most of
these genes are clustered and their coordinated transcription is
controlled in a complex way by both narrow pathway-specific
regulators as well as broad global transcription factors responsive
to environmental cues. In recent years it was discovered many of
the newly identified gene clusters are silent under laboratory
conditions suggesting that the biosynthetic potential of fungi is
far from being exploited. Besides identifying novel bioactive
metabolites from still unexplored sources, the activation of these
gene clusters by several approaches may result in the discovery of
new substances with antibiotic and pharmaceutical benefits. This
book covers recent advances in the field of fungal secondary
metabolisms ranging from methodologies to biological aspects and
will include the latest knowledge on fungal molecular biology,
genomics, and metabolomics. With the related volume by Professor
Juan-Francisco Martin, where the most relevant and well-studied
fungal secondary metabolites are compiled, this book provides a
comprehensive overview of the state-of-the-art of research on
fungal secondary metabolites.
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