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Natural Products Chemistry III (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R4,529
Discovery Miles 45 290
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Natural Products Chemistry III (Paperback, Softcover reprint of the original 1st ed. 1988)
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Natural product chemistry has undergone an explosive growth during
the latter half of the current century. This has been brought about
by a number of factors. One of these has been the growing number of
sub stances from natural sources which display interesting
pharmacological activities. These include antibiotics, anti-tumor
agents, immunostimu lants, drugs affecting the cardiovascular and
central nervous systems, analgesics etc. Another factor has been
the improvements made in the technology of isolation processes
which includes the development of such techniques as high pressure
liquid chromatography which has al lowed the rapid isolation of
substances which were previously diffi cult to obtain by classical
procedures. The most important factor has been the development of
new spectrosopic techniques which have opened up whole new vistas
in this exciting field. Prominent in these advan ces has been the
advent of powerful superconducting magnets with very stable
magnetic fields, and pulse NMR in which the duration, direction and
phases of pulses can be accurately controlled by means of mini
computers. These have heralded the advent of two-dimensional NMR
spec troscopy which has now come to be routinely employed in
unravelling complex structures. No less important, though somewhat
less dramatic, have been the advances made in the field of mass
spectroscopy where new ionization techniques such as positive and
negative fast atom bom bardment, field desorption, chemical
ionization etc. have allowed the mass spectra of larger
non-volatile substances to be recorded. The field of organic
synthesis has seen equally rapid advances."
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