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Vertebrate Photoreceptors - Functional Molecular Bases (Paperback, Softcover reprint of the original 1st ed. 2014)
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Vertebrate Photoreceptors - Functional Molecular Bases (Paperback, Softcover reprint of the original 1st ed. 2014)
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This book provides a series of comprehensive views on various
important aspects of vertebrate photoreceptors. The vertebrate
retina is a tissue that provides unique experimental advantages to
neuroscientists. Photoreceptor neurons are abundant in this tissue
and they are readily identifiable and easily isolated. These
features make them an outstanding model for studying neuronal
mechanisms of signal transduction, adaptation, synaptic
transmission, development, differentiation, diseases and
regeneration. Thanks to recent advances in genetic analysis, it
also is possible to link biochemical and physiological
investigations to understand the molecular mechanisms of vertebrate
photoreceptors within a functioning retina in a living animal.
Photoreceptors are the most deeply studied sensory receptor cells,
but readers will find that many important questions remain. We
still do not know how photoreceptors, visual pigments and their
signaling pathways evolved, how they were generated and how they
are maintained. This book will make clear what is known and what is
not known. The chapters are selected from fields of studies that
have contributed to a broad understanding of the birth,
development, structure, function and death of photoreceptor
neurons. The underlying common word in all of the chapters that is
used to describe these mechanisms is "molecule". Only with this
word can we understand how these highly specific neurons function
and survive. It is challenging for even the foremost researchers to
cover all aspects of the subject. Understanding photoreceptors from
several different points of view that share a molecular perspective
will provide readers with a useful interdisciplinary perspective.
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