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Hepatitis C Virus I - Cellular and Molecular Virology (Paperback, Softcover reprint of the original 1st ed. 2016)
Loot Price: R6,240
Discovery Miles 62 400
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Hepatitis C Virus I - Cellular and Molecular Virology (Paperback, Softcover reprint of the original 1st ed. 2016)
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This volume is composed of chapters that review important
fundamental aspects of HCV biology and disease pathogenesis
including, for example, the discovery and identification of the HCV
genome, early virus-cell interactions including identification of
various cellular receptors, HCV gene expression studied using the
HCV replicon system, identification and characterization of HCV
structural- and non-structural HCV proteins, HCV replication in
cultured cells, and host factors involved in viral replication.
This volume also contains chapters dealing with immunity to HCV
infection and pathogenesis. This is particularly important in
understanding hepatitis C because HCV infection alone is not cell
lytic. Mechanisms underlying the persistent nature of HCV infection
are also discussed in these chapters. Many of the authors published
articles that were listed among the "top 10 papers" published in
the 24 years since HCV was discovered in 1989. Their citations are
above 1,000 (Web of Science). The authors describe the background
and significance of their contributions to the field in the context
of findings from other research groups.
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