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Free Radicals in Medicine (Hardcover)
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Free Radicals in Medicine (Hardcover)
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The role of reactive oxygen species and other free radicals in
normal and disease processes has become a major area of interest in
the medical scientific community. In the past 30 years, this area
of study has advanced from outright rejection, to general
acceptance, to intense study. While there is still some dispute as
to the exact role of these highly reactive molecules in pathology,
it is clear that they are present in and influence many biological
processes. This book provides an overview of the possible
biological effects of reactive oxygen species and other free
radicals with an emphasis on pathology. The various types of free
radicals that may affect the body are discussed along with the
potential sources of free radicals, both internal and external to
the body. The extensive defenses the body raises against the
effects of these molecules in the form of enzymatic and
non-enzymatic antioxidants is reviewed. A variety of conditions in
which free radicals have been proposed to play a role are
discussed. These include the physiological effects of oxygen stress
in aging, exercise, and pregnancy. Pathologic conditions discussed
include cancer, liver cirrhosis, respiratory problems, and others.
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