The Antibody Enigma is a somewhat personal view of the antibody
diversity question from two investigators who have spent the past
18 years trying to penetrate the enigma. It is not and was not
meant to be an all-embracing comprehensively referenced review of
the subject of antibody diversity. Because of the subjective
viewpoint, there are un doubtedly omissions of data that others
consider to be seminal, and if we have offended anyone by omitting
their own contribution we sin cerelyapologize. We have lived with
"The Enigma" on and off for the past two years. It has been both
hard work and good fun but, above all, it has been a learning
experience. There were several difficult decisions to make in
putting together the final text, but perhaps the most difficult was
de ciding upon a stopping point. The field of antibody diversity is
presently enjoying an unparalleled expansion of information, and
because of this it was very tempting to await further developments
in hopes of tying up as many loose ends as possible. This was
decided against for several reasons; the major factor was that the
project was growing burdensome for both of us. From a more
objective point of view this appears to be a reasonable time to
stop our exposition."
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