Computer Simulation Study of Collective Phenomena in Dense Suspensions of Red Blood Cells under Shear (Paperback, 2012 ed.)

The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition.

General

Imprint:	Vieweg+teubner Verlag
Country of origin:	Germany
Release date:	July 2012
First published:	2012
Authors:	Timm Kruger
Dimensions:	240 x 168 x 10mm (L x W x T)
Format:	Paperback
Pages:	165
Edition:	2012 ed.
ISBN-13:	978-3-8348-2375-5
Categories:	Books > Computing & IT > Applications of computing > Computer modelling & simulation Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN:	3-8348-2375-9
Barcode:	9783834823755

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