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Mechanisms of Organ Dysfunction in Critical Illness (Hardcover, 2002 ed.)
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Mechanisms of Organ Dysfunction in Critical Illness (Hardcover, 2002 ed.)
Series: Update in Intensive Care and Emergency Medicine, 38
Expected to ship within 10 - 15 working days
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The pathophysiology of sepsis can be regarded as a series of steps,
beginning with the invasion of normally sterile tissue by microbes
and the elaboration of various pro-inflammatory mediators. The
final common pathway is often the development of the multiple organ
dysfunction syndrome (MODS). Whereas a great deal has been learned
during the past quarter century about the inflammatory processes
associated with sepsis (and other related conditions, such as
ischemia/reperfusion injury), our understanding is far less
developed with respect to the pathophysiological events that lead
to organ dysfunction under these conditions. Nevertheless, efforts
by both clinical and laboratory scientists are leading to new
knowledge in this area. The chapters in this volume provide a
state-of-the-art overview of many aspects of the pathophysiology of
organ dysfunction in critical illness.
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