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Personalized Pathway-Activated Systems Imaging in Oncology - Principal and Instrumentation (Hardcover, 1st ed. 2017)
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Personalized Pathway-Activated Systems Imaging in Oncology - Principal and Instrumentation (Hardcover, 1st ed. 2017)
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This comprehensive volume covers radiopharmaceuticals developed for
pathway-directed systems in imaging and theranostic applications.
We now are at the cutting edge of providing personalized treatment
with increased use in oncology of these new radiopharmaceuticals.
Trends in high-resolution instrumentation development, quality
assurance systems and regulatory compliance for
radiopharmaceuticals, clinical evaluation of radiopharmaceuticals,
and benefits and pitfalls of the current clinical FDG PET are
discussed. Radiopharmaceuticals are used for diagnosis of diseases
of the central nervous and cardiovascular systems and for staging,
restaging, and treatment planning for cancers. Nuclear biomarkers
allow precise measurement of molecular pathways on a whole-body
image upon administration of functional radiolabeled agents, and
nuclear imaging agents have potential use in patient selection,
pharmacokinetic, dosage-finding, and proof-of-concept studies.
Nuclear imaging agents and hybrid instrumentation also provide
sensitive and specific answers for differential responsiveness in
therapeutic outcome. This book serves as a reference for moving the
discovery and development of radiopharmaceuticals from the
workbench to clinical applications. It thus benefits not only
clinicians but also translational research scientists-molecular
biologists, chemists, imaging scientists, pharmaceutical
developers, physicists, and support staff.
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