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Minimal Residual Disease in Melanoma - Biology, Detection and Clinical Relevance (Paperback, Softcover reprint of the original 1st ed. 2001)
Loot Price: R2,943
Discovery Miles 29 430
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Minimal Residual Disease in Melanoma - Biology, Detection and Clinical Relevance (Paperback, Softcover reprint of the original 1st ed. 2001)
Series: Recent Results in Cancer Research, 158
Expected to ship within 10 - 15 working days
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Knowledge about diagnostic procedures in melanoma has in creased
rapidly within the past few years. Single tumor cells have been
identified in normal tissue such as sentinel lymph nodes, as well
as in bone marrow, peripheral blood, and other bodily fluids and
cells, by molecular technologies. The introduction of polymerase
chain reaction-based methods can be regarded as a prototype of this
dramatic development towards molecular approaches in new diagnostic
procedures. This fact opens up the possibility of clinical use in
patients and of influencing treatment strategies. Considerable
discrepancies have been described, how ever, in the success rates
of these new techniques for the detec tion of minimal residual
disease in cancer patients. Despite fav orable results reported by
different groups of investigators, it will take several years to
define the clinical and pathophysiological relevance of new
diagnostic procedures. The 1st International Symposium "Minimal
Residual Disease in Melanoma: Biology, Detection and Clinical
Relevance of Microme tastases", held in September 1999 in
Homburg/Saar, Germany, fo cused on recent developments in this
particular area of cancer re search. The purpose of the meeting was
to stimulate discussion and exchange of new data and ideas by
renowned international scientists. The aim of this volume is to
summarize major topics of basic research and clinical
investigations presented by invited experts in this fascinating but
still. controversial field of melanoma re search.
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