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Erythrocytes as Drug Carriers in Medicine (Hardcover, 1997 ed.)
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Erythrocytes as Drug Carriers in Medicine (Hardcover, 1997 ed.)
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The sixth meeting on the use of resealed annealed red blood cells
was held in Irsee, Germany by the International Society for the Use
of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although
earlier meetings focused on the technology toward develop ment of
methods and standardization for efficient, consistent
encapsulation, most of the present studies now are directed toward
the application use of these carrier blood cells. Basic studies now
have been directed toward exploration of commercial applications.
In deed, clinical trials were initiated to evaluate the
dose-response curves employing L asparagenase in human patients.
Also, studies have shown the use of thrombolytic agent in
erythrocyte carriers with the use of human red blood cells to
provide a new conceptual ap proach in thrombolytic therapy to
prevent thrombosis in individuals with higher risk fac tors. For
example, with the use of carrier red blood cells, the thrombolytic
agents will have a greater potential of acting on clot formation
without systemic activation and thus lower the risk of hemorrhage,
which is always prevalent in the thrombolytic therapy."
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