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Metals in Cells (Hardcover)
Loot Price: R4,772
Discovery Miles 47 720
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Metals in Cells (Hardcover)
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Over the last three decades a lot of research on the role of metals
in biochemistry and medicine has been done. As a result many
structures of biomolecules with metals have been characterized and
medicinal chemistry studied the effects of metal containing drugs.
This new book (from the EIBC Book Series) covers recent advances
made by top researchers in the field of metals in cells [the
metallome ] and include: regulated metal ion uptake and
trafficking, sensing of metals within cells and across tissues, and
identification of the vast cellular factors designed to orchestrate
assembly of metal cofactor sites while minimizing toxic side
reactions of metals. In addition, it features aspects of metals in
disease, including the role of metals in neuro-degeneration, liver
disease, and inflammation, as a way to highlight the detrimental
effects of mishandling of metal trafficking and response to
"foreign" metals. With the breadth of our recently acquired
understanding of metals in cells, a book that features key aspects
of cellular handling of inorganic elements is both timely and
important. At this point in our understanding, it is worthwhile to
step back and take an expansive view of how far our understanding
has come, while also highlighting how much we still do not know.
The content from this book will publish online, as part of EIBC in
December 2013, find out more about the Encyclopedia of Inorganic
and Bioinorganic Chemistry, the essential online resource for
researchers and students working in all areas of inorganic and
bioinorganic chemistry.
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