Handbook on Estrogen Receptors in the Brain (Paperback)

The present book covers estrogen, its receptors and estrogen mediated gene regulation in the brain. Further, it explains the mechanism of estrogen action and dysfunction leading to diseases. Briefly, estrogen mediates its multiple functions in the brain through two well-characterised receptors: ER and ER . Upon binding with estrogen, ER recruits coregulators, which are responsible for tissue specific regulation. When coregulators activate the transcription of a particular gene, they become coactivators; when they repress the activity of particular gene, they are called corepressors. These coregulators make a bridge between the basal transcription machinery and the receptors by protein-protein interaction. Estrogen disrupters are also explained in this book. Furthermore, the role of estrogen and its receptors are explained in the context of aging. Taken together, this book shall be self-explanatory concerning estrogen action in the brain in various aspects. Therefore, it is intended for researchers interested in the aforementioned aspects.

General

Imprint:	nova science publishers
Country of origin:	United States
Release date:	December 2016
Authors:	Vijay Paramanik
Dimensions:	230 x 155 x 8mm (L x W x T)
Format:	Paperback
Pages:	60
ISBN-13:	978-1-5361-0087-7
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Promotions
LSN:	1-5361-0087-0
Barcode:	9781536100877

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