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Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitatsforschung (Paperback, Softcover reprint of the original 1st ed. 1969)
Loot Price: R2,940
Discovery Miles 29 400
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Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitatsforschung (Paperback, Softcover reprint of the original 1st ed. 1969)
Series: Current Topics in Microbiology and Immunology, 48
Expected to ship within 10 - 15 working days
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The study of streptococcal infections and their sequelae has in the
last two decades yielded several important findings on the
biological properties of cellular and extracellular products of
group A streptococci. These findings have contributed to a better
knowledge of the pathological reactions occurring in the
macroorganism during host-parasite interactions. Nevertheless, the
pathogenesis of streptococcal infections is not fully understood.
So far there has been no success in eliciting experimentally,
either through the action of the substances isolated from the cell,
or from broth culture filtrate of group A streptococci, symptoms
that are fully identical with any type of acute streptococcal
infection. It also has not been possible to explain the
mUltiplicity of clinical and histological changes caused by
streptococci as being due solely to anyone of these substances or a
combination thereof. The same applies to the sequelae of
streptococcal infections, rheumatic fever and acute
glomerulonephritis. We do not know how the group A strepto coccus
elicits these diseases and we have only a partial understanding of
the pathological processes, initiated by this streptococcus, and
resulting in cardiac or renal lesions. It is clear that an organism
infected by streptococci is exposed to the action of a complex of
substances. A more detailed recognition of the biological activity
of the single components and their combination under defined
experimental conditions may be capable, it is hoped, to explain the
pathologic processes triggered in the course. of the development of
group A streptococcal infection."
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