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Autophagy, Infection, and the Immune Response (Hardcover)
Loot Price: R3,869
Discovery Miles 38 690
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Autophagy, Infection, and the Immune Response (Hardcover)
Expected to ship within 12 - 17 working days
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The relationship between infection and immunity and autophagy, a
pathway of cellular homeostasis and stress response, has been a
rapidly growing field of study over the last decade. While some
cellular processes are pro- or anti-infection, autophagy has been
proven to be both: a part of the innate immune response against
some microbes, and a cellular pathway subverted by some pathogens
to promote their own replication. Autophagy, Infection, and the
Immune Response provides a unified overview of the roles of
cellular autophagy during microbial infection. Introductory
chapters ground the reader by delineating the autophagic pathway
from a cellular perspective, and by listing assays available for
measuring autophagy. Subsequent chapters address virus interactions
with autophagy machinery, the various roles of autophagy parasitic
infection, and interactions of bacteria with the autophagic
pathway. Concluding chapters explore the relationships of autophagy
to systemic immune responses, including antigen presentation, ER
stress, and production of IFN-gamma. Designed as a resource for
those interested in initiating studies on the relationship between
autophagy and infection or immunity, Autophagy, Infection, and the
Immune Response combines practical state-of the art technique
descriptions with an overview of the wide variety of known
interactions between pathogens and the autophagic pathway.
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