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MicroRNA and Cancer - Methods and Protocols (Hardcover, Edition.)
Loot Price: R3,008
Discovery Miles 30 080
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MicroRNA and Cancer - Methods and Protocols (Hardcover, Edition.)
Series: Methods in Molecular Biology, 676
Expected to ship within 10 - 15 working days
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The tiny microRNAs (miRNAs) can have huge impacts on the regulation
of a variety of genes and play crucial roles in the fundamental
cellular processes. Recent miRNA studies change the landscape of
cancer genetics by scrutinizing the alterations of genome-wide
miRNA expressions in most common cancers and their regulatory
functions during the development of cancer. The connections between
miRNAs and cancer are widespread enough to warrant more
comprehensive investigations in the systems biology perspective. In
MicroRNA and Cancer: Methods and Protocols, internationally
renowned experts provide the latest miRNA knowledge, the various
techniques and methodologies currently available for cancer
research application. Ranging from the fundamental concepts to
practical applications, this book presents: * Overview of microRNA
biogenesis, computational prediction of new miRNAs in the cancer
genome, and miRNA-based therapeutic approaches for cancer treatment
* Detailed experimental protocols in miRNA detection with novel and
high-throughput technology, miRNA library cloning, miRNA epigenetic
regulation, and miRNA pathway study * Stepwise computational and
bioinformatic procedures for miRNA complex networks in cancer
genomes with a variety of softwares and programs * Cross-cited
notes on troubleshooting and avoiding known pitfalls Authoritative
and cutting-edge, MicroRNA and Cancer: Methods and Protocols serves
researchers with the basic principles of experimental and
computational methods for microRNA study in cancer research and
provides a firm grounding for those who wish to further develop
their own applications and tailor them to their own specific
research needs.
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