Sirtuins in Health and Disease, Volume 154 (Hardcover)

Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington's Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins - substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Progress in Molecular Biology and Translational Science
Release date:	2018
First published:	2018
Volume editors:	Weiping Zheng
Dimensions:	229 x 152mm (L x W)
Format:	Hardcover
Pages:	186
ISBN-13:	978-0-12-812261-7
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	0-12-812261-7
Barcode:	9780128122617

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