Modern medical imaging and radiation therapy technologies are so
complex and computer driven that it is difficult for physicians and
technologists to know exactly what is happening at the point-of-
care. Medical physicists responsible for filling this gap in
knowledge must stay abreast of the latest advances at the
intersection of medical imaging and radiation therapy. This book
provides medical physicists and radiation oncologists current and
relevant information on Adaptive Radiation Therapy (ART), a state-
of-the-art approach that uses a feedback process to account for
patient-specific anatomic and/or biological changes, thus
delivering highly individualized radiation therapy for cancer
patients. The book should also benefit medical dosimetrists and
radiation therapists. Adaptive Radiation Therapy describes
technological and methodological advances in the field of ART, as
well as initial clinical experiences using ART for selected
anatomic sites. Divided into three sections (radiobiological basis,
current technologies, and clinical applications), the book covers:
*Morphological and biological biomarkers for patient-specific
planning *Design and optimization of treatment plans *Delivery of
IMRT and IGRT intervention methodologies of ART *Management of
intrafraction variations, particularly with respiratory motion
*Quality assurance needed to ensure the safe delivery of ART *ART
applications in several common cancer types / anatomic sites The
technology and methodology for ART have advanced significantly in
the last few years and accumulated clinical data have demonstrated
the need for ART in clinical settings, assisted by the wide
application of intensity modulated radiation therapy (IMRT) and
image-guided radiation therapy (IGRT). This book shows the real
potential for supplying every patient with individualized radiation
therapy that is maximally accurate and precise.
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