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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Cullin-RING Ligases and Protein Neddylation - Biology and Therapeutics (Paperback, 1st ed. 2020)
Loot Price: R4,541
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Cullin-RING Ligases and Protein Neddylation - Biology and Therapeutics (Paperback, 1st ed. 2020)
Series: Advances in Experimental Medicine and Biology, 1217
Expected to ship within 10 - 15 working days
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This book summarizes all the important aspects of CRLs (Cullin-RING
E3 Ubiquitin Ligases), while providing details of mechanistic
specifics that go beyond protein ubiquitination and neddylation.
Ubiquitin ligases, including the CRLs, which are activated by
neddylation, play an important role in diverse biological processes
and are involved in various human diseases, particularly cancer.
The book covers various topics, such as CRL structure, biology,
genetics, its regulation by neddylation, its pivotal role in human
disease, and its potential in drug discovery and targeted
therapies. The book appeals to biochemists and biologists working
in other fields, and, given the importance of CRLs in all aspects
of cell biology and the great promise of targeting these complexes
for therapy, is a valuable resource anyone interested in modern
biology or medicine.
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