0
Your cart

Your cart is empty

Books > Science & Mathematics > Biology, life sciences > Biochemistry > Toxicology (non-medical)

Buy Now

Toxicology of Glutathione Transferases (Hardcover) Loot Price: R5,555
Discovery Miles 55 550
Toxicology of Glutathione Transferases (Hardcover): Yogesh C. Awasthi

Toxicology of Glutathione Transferases (Hardcover)

Yogesh C. Awasthi

 (sign in to rate)
Loot Price R5,555 Discovery Miles 55 550 | Repayment Terms: R521 pm x 12*

Bookmark and Share

Expected to ship within 12 - 19 working days

Since the discovery of Glutathione S-Transferase (GST) or Glutathione transferase, studies have probed important questions about its pharmacological and physiological significance. Toxicology of Glutathione Transferases is the only text that details the methods used in GST research. With chapters written by experts who have been involved in all areas of GST research and have actively contributed to the progress of this field, the book describes the role of GSTs in toxicology, focusing on their pharmacologic and physiologic roles and their relevance to biological toxicology. The book provides current information on gene families, structure and regulation of gene expression, reaction mechanisms and substrates, three-dimensional structures of GSTs, design of proteins with GST activity, and various approaches to developing inhibitors that overcome drug resistance. It also covers the physiological significance and the mechanisms of activation of microsomal GSTs. carcinogens and possible implications of GST polymorphism in human health and disease, make the volume useful to researchers in the field of pharmacology and toxicology. Chapters cover the possible and exciting role of GSTs in defense mechanisms against chronic oxidative stress-linked disorders such as atherosclerosis and the newly emerging area of GST-mediated modulation of stress-signaling through its catalytic as well as binding activities. They explore an intriguing hypothesis that strongly suggests an important role of the factors that modulate the GSH-electrophile conjugate (GS-E) homeostasis in the regulation of cellular processes. Chapters on known and potential endogenous electrophilic substrates and a major role of GSTs in suppressing stress-induced lipid peroxidation reinforce this newly emerging role of GSTs. These are just a few of the features that make the book helpful to clinicians involved in basic as well as translational research, particularly those studying oxidative stress-related degenerative diseases.

General

Imprint: Crc Press
Country of origin: United States
Release date: July 2006
First published: 2007
Editors: Yogesh C. Awasthi
Dimensions: 234 x 156 x 27mm (L x W x T)
Format: Hardcover
Pages: 375
ISBN-13: 978-0-8493-2983-8
Categories: Books > Science & Mathematics > Biology, life sciences > Biochemistry > Toxicology (non-medical)
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
Promotions
LSN: 0-8493-2983-3
Barcode: 9780849329838

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!

You might also like..

The Poisoners - On South Africa's Toxic…
Imraan Coovadia Paperback R320 R174 Discovery Miles 1 740
Handbook of Arsenic Toxicology
Swaran Jeet Singh Flora Hardcover R4,620 Discovery Miles 46 200
Advances in Marine Biology, Volume 79
Charles Sheppard Hardcover R4,593 Discovery Miles 45 930
Chiral Pesticides - Stereoselectivity…
A. Wayne Garrison, Jay Gan, … Hardcover R2,899 Discovery Miles 28 990
Advances in Human Vector Control
J. Marshall Clark, Jeffrey Bloomquist, … Hardcover R2,781 Discovery Miles 27 810
Neurotoxicity of Drugs of Abuse, Volume…
Lucio G. Costa, Michael Aschner, … Hardcover R5,906 R4,940 Discovery Miles 49 400
Occupational Neurotoxicology, Volume 7
Michael Aschner, Lucio G. Costa, … Hardcover R5,922 R4,957 Discovery Miles 49 570
Marine Neurotoxins, Volume 6
Antonello Novelli, Maria Teresa Fernandez Sanchez, … Hardcover R6,617 R5,536 Discovery Miles 55 360
Pharmaceuticals in Marine and Coastal…
Juan Carlos Duran-Alvarez, Blanca Jimenez-Cisneros Paperback R4,213 Discovery Miles 42 130
Drink? - The New Science of Alcohol and…
David Nutt Paperback R469 R438 Discovery Miles 4 380
Neurotoxicity of Metals: Old Issues and…
Michael Aschner, Lucio G. Costa Hardcover R5,929 R4,964 Discovery Miles 49 640
Animal Feed Additives
Pankaj Singh Hardcover R4,966 Discovery Miles 49 660

See more

Partners