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Behcet's Disease - From Genetics to Therapies (Hardcover, 2015 ed.)
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Behcet's Disease - From Genetics to Therapies (Hardcover, 2015 ed.)
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This book, besides reviewing basic and clinical aspects of Behcet's
disease, covers the latest findings, including genetic studies and
treatment with biologics for the disease. Although the cause of
Behcet's disease is still unknown, it is well known that genetic
factors, such as HLA-B51, are involved in its development.
Recently, novel susceptibility loci including IL10, IL23R-IL12RB2,
and endoplasmic reticulum aminopeptidase 1 have been identified,
providing new insights into the pathogenesis of the disease. In
addition to basic research, the beneficial efficacy of
anti-TNF-alpha monoclonal antibodies has also been suggested for
not only uveitis associated with the disease but also other
subtypes of the disease such as entero-, vasculo-, and neuro-
Behcet's disease. Behcet's Disease: From Genetics to Therapies
provides essential information both for basic researchers working
in the fields of immunology, inflammation, and genetics, and for
clinical physicians who are interested in Behcet's disease, such as
ophthalmologists, rheumatologists, dermatologists,
gastroenterologists, neurologists, and vascular surgeons.
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