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Amino-Acid Homopolymers Occurring in Nature (Paperback, 2010 ed.)
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Amino-Acid Homopolymers Occurring in Nature (Paperback, 2010 ed.)
Series: Microbiology Monographs, 15
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Microorganisms are capable of producing a wide variety of
biopolymers. Homopolymer peptides, which are made up of only a
single type of amino acid, are far less ubiquitous. The only two
amino-acid homopolymers known to occur in nature are presented in
this volume. Poly-epsilon-L-lysine is a polycationic peptide and
exhibits antimicrobial activity against a wide spectrum of
microorganisms. It is both safe and biodegradable and is therefore
used as a food preservative in several countries. In addition,
there has been great interest in medical and other applications of
poly-lysine and its derivatives. In contrast, poly-gamma-glutamic
acid is an unusual anionic polypeptide. It is also water soluble,
biodegradable, edible, non-toxic and non-immunogenic and can be
chemically modified to introduce various drugs. These features are
very useful for pharmaceutical and biomedical applications.
Poly-glutamic acid is also a highly attractive as a food
ingredient.
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