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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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An Introduction to Single Molecule Biophysics (Hardcover)
Loot Price: R4,144
Discovery Miles 41 440
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An Introduction to Single Molecule Biophysics (Hardcover)
Series: Foundations of Biochemistry and Biophysics
Expected to ship within 12 - 17 working days
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This book gives an accessible, detailed overview on techniques of
single molecule biophysics (SMB), showing how they are applied to
numerous biological problems associated with understanding the
molecular mechanisms of DNA replication, transcription, and
translation, as well as functioning of molecular machines. It
covers major single molecule imaging and probing techniques,
highlighting key strengths and limitations of each method using
recent examples. The chapters begin with a discussion of single
molecule fluorescence techniques followed by an overview of the
atomic force microscope and its use for direct time-lapse
visualization of dynamics of molecular complexes at the nanoscale,
as well as applications in measurements of interactions between
molecules and mechanical properties of isolated molecules and their
complexes. The next chapters address magnetic tweezers and optical
tweezers, including instrumentation, fundamentals of operation, and
applications. A final chapter turns to nanopore transport and
nanopore-based DNA sequencing technology that will play a major
role in next-generation genomics and healthcare applications.
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