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Clinical and Biological Basis of Lung Cancer Prevention (Paperback, Softcover reprint of the original 1st ed. 1998)
Loot Price: R1,522
Discovery Miles 15 220
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Clinical and Biological Basis of Lung Cancer Prevention (Paperback, Softcover reprint of the original 1st ed. 1998)
Series: Respiratory Pharmacology and Pharmacotherapy
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Lung cancer is a disease with pandemic public health implications
as it is now the leading cause of cancer mortality throughout the
world. This book results from two recent International Association
for the Study of Lung Cancer (IASLC) Workshops on lung cancer
prevention. It strikes a balance between considering public health
approaches to tobacco control and population-based screening,
advances in clinical evaluation of chemoprevention approaches, and
the biology of lung carcinogenesis. Indeed, while the science of
smoking cessation is evolving as new pharmacological tools are
moving into clinical evaluation, the current impact of molecular
diagnostics is profound. The rapidly-evolving diagnostic
technologies are revolutionizing basic scientific investigation of
cancer, and this trend is expected to soon spill over into the
clinical practice of medicine. The evolution of economical
diagnostic platforms to allow for direct bronchial epithelial
evaluation in high-risk populations promises to improve the
diagnostic lead-time for this disease. The hope is that enough
progress will occur to permit lung cancer detection in advance of
clinical cancer so that the disease can be addressed early on,
while it is still confined to the site of origin. Chemoprevention,
which is designed to intervene in the early phase of carcinogenesis
prior to any subjective clinical manifestation of a cancer, is also
generating greater research interest. Moreover, the benefit of
aerosolized administration of chemoprevention agents over
conventional oral administration has strong appeal and may result
in the reduction of the incidence of cancer when combined with new
diagnostic technologies.
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