Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications.

How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students. The book covers the foundations of molecular pharmacology and the main drug classes, including detailed information on their mechanisms of action and the application of molecular pharmacology in drug development. This book is an ideal reference for graduate students and researchers in pharmacology, however, researchers in corporate settings will also benefit from the book's structured and detailed coverage of mechanisms of action of synthetic drugs.

A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology.

As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications.
Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications.
Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field.
Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devicesConsiders the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wiresConsiders the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Medical imaging now plays a major role in diagnosis, choice of therapy, and follow-up. However, patients are often intimidated by the multiple imaging modalities available, the indications for their use, the imposing equipment, what the examinations are like and how long they last, and the advantages and disadvantages of various procedures. This book is designed to provide explanations for these and other issues in order to relieve some of the anxiety related to medical imaging studies.

Peter J. Jannetta, the neurosurgeon/neuroscientist who has contributed so much to the evaluation and treatment of trigeminal neuralgia and other cranial nerve disorders brings together the most distinguished contributors in Trigeminal Neuralgia.
This seminal work collates and categorizes in one succinct volume what we understand about the various forms of face pain syndromes. By providing information on former beliefs, as well as current understanding, this book provides multiple options regarding diagnosis, medical treatment and operative intervention which will help decision making, develop knowledge and improve care of patients.
Trigeminal Neuralgia begins with an Introduction explaining where we were and what role those ideas have played in current thinking, all with the goal of giving the reader a basis for future thought. With each subsequent chapter - written by basic scientists and astute clinicians working in the area of facial pain - enigmas are clarified, solutions of apparently untreatable problems are presented, and a better understanding of how diagnoses and pathophysiology are evolving are presented.
This is a must read for all who would learn about neurogenic facial pain.

The life and work of Joseph Babinski (1857-1932) has been revisited by two French physicians whose enthusiasm for the subject is reflected in the depth and breadth of documentary sources. From Babinski's Polish roots, his father (an intrepid revolutionist, his brother(the gold miner and famous gastronome Ali-Bab to the Babinski circle, his friends, his colleagues and his disciples, the reader will find a refreshing perspective on a particularly fascinating period in French medicine. His scientific contribution is analyzed in detail, with for the first time a complete bibliography of his publications. These includes not only the Babinski Sign, but also the earlier and heretofore less-known concerning pathological anatomy and histology, the papers on cutaneous and tendinous reflexes, cerebellar and vestibular semeiology, hysteria and pithiatism, localization of spinal cord compression s and the birth of French neurosurgery.

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, measured by major advances, the greatest decade in the history of brain studies was mid-twentieth century, especially the 1950s. The first to focus on worldwide contributions in this period, the book ranges through dozens of astonishing discoveries at all levels of the brain, from DNA (Watson and Crick), through growth factors (Hamburger and Levi-Montalcini), excitability (Hodgkin and Huxley), synapses (Katz and Eccles), dopamine and Parkinson's (Carlsson), visual processing (Hartline and Kuffler), the cortical column (Mountcastle), reticular activating system (Morruzzi and Magoun) and REM sleep (Aserinsky), to stress (Selye), learning (Hebb) and memory (HM and Milner). The clinical fields are also covered, from Cushing and Penfield, psychosurgery and brain energy metabolism (Kety), to most of the major psychoactive drugs in use today (beginning with Delay and Deniker), and much more.
The material has been the basis for a highly successful advanced undergraduate and graduate course at Yale, with the classic papers organized and accessible on the web. There is interest for a wide range of readers, academic, and lay because there is a focus on the creative process itself, on understanding how the combination of unique personalities, innovative hypotheses, and new methods led to the advances. Insight is given into this process through describing the struggles between male and female, student and mentor, academic and private sector, and the roles of chance and persistence. The book thus provides a new multidisciplinary understanding of the revolution that created the modern field of neuroscience and set the bar for judging current and future advances.

Psychiatry is arguably the most misunderstood specialty in modern medicine and psychiatrists are often thought of as part physician, part confessor, part police officer, and part shaman. In Demystifying Psychiatry, two eminent psychiatrists offer an illuminating look at the entire field, offering a clear and informative portrait of a medical specialty often clouded in myth. Zorumski and Rubin range from a basic discussion of what psychiatry is, to the types of illnesses psychiatrists treat, the training of psychiatrists, the treatment of psychiatric disorders (covering medications, psychotherapy, lifestyle interventions, electroconvulsive therapy, and much more), and how families can help with treatment. They caution the consumer about practices that should raise red flags. The book also covers new trends in psychiatry and explores the future of the field, predicting that major advances in genetics and neuroscience will lead to rapid and amazing changes in psychiatry. The book concludes with extensive reference materials that will be valuable both to general readers and medical practitioners.

When it comes to natural medicines, such as herbs, vitamins, and dietary supplements, you want to make sure you're getting the truth about what works, what is safe, and what is a waste of money. You need evidence-based, trustworthy, unbiased sources and studies so that you can make wise decisions for yourself and your family. In consultation with the experts at ConsumerLab.com and Natural MedicinesTM, Dr. Walt Larimore has combed the available research from around the globe to evaluate about 1300 natural medicines or interventions for more than 500 conditions or indications summarized in helpful charts and tables. This highly readable and reliable guide will tell you what natural medicines have proven to be both safe and effective while suggesting the best-value "Top Picks" for health issues such as - brain and heart health - digestive and immune health - energy and fatigue - losing weight - keeping hair, skin, and nails young - increasing the quality and length of your life - and many more Arranged topically so you can go directly to the information you need, this comprehensive, trustworthy guide is a resource you'll return to again and again. Praise for The Natural Medicine Handbook "I highly recommend this informative book. In it you will find reliable, independent evidence that will help inform your health-related decisions."--Donal O'Mathuna, PhD "A much-needed and intensely evidence-based resource. . . . Anyone reading this book will gain the skills needed to ask and answer the right questions about whether to and how to incorporate natural medicines as part of their healthy lifestyle."--Reid B. Blackwelder, MD, FAAFP "An entirely digestible and ultimately useful guide for patients and practitioners alike."--Matthew A. Ciorba, MD "Navigating the landscape of herbs, vitamins, and supplements can be particularly complex and treacherous. Dr. Larimore's approach is direct and comprehensive and will certainly help numerous patients and their families make informed and safe decisions."--Jacob N. Hall, MD