The ideals of simple country living have captivated poets for a crow's age. But in the countryside that Tityrus knows, the beech trees tower like skyscrapers, mice wrestle each other, and the nearby island is infected by swarms of gulls. The forest is a source of energy, but also the home of a behemoth transformer substation and where a little boy has drowned. The shepherds are prescribed Ritalin, slip in the mud, cry without knowing why, and sustain themselves on mini pizza rolls. Wiese's poetry is as hilarious as it is gentle, moving gracefully between the everyday and the profound. Building with the narrative quality of a novel, Tityrus is both an elegy to a natural world that has long been overindustrialised, and a love letter to all that remains.

International Business is a well-established research field, in which regionalisation has recently gained significant prominence. Europe comprises marketplaces characterised by unique patterns of highly advanced economic integration. No other marketplace in the world has progressed to the same levels of harmonisation across sovereign countries and economies. European Business is a subject in its own right with its own research momentum. Contemporary research evidences that firms view Europe as a challenging, mostly - yet not entirely - mature market location. Yet this location, often seen from a multi-country perspective, is subject to complexities revealing strategic corporate strengths and weaknesses. Theory, concepts and models known from International Business hence often vary in their applicability and relevance in this business environment. This comprehensive reference volume brings together a global team of contributors to analyse and overview the key issues, themes and phenomena that affect business in Europe. With interdisciplinary perspectives, the book covers crucial themes that any European Business research needs to acknowledge, including business cultures and identity, entrepreneurship and innovation, M&A and institutional trends, European HRM, migration, climate change issues, Brexit, and more. The selection of authors, from 17 countries worldwide, reflects the international scope of this research field and its agenda. A unique resource, this book provides an essential guide to researchers, research students and scholars of business and the social sciences, as well as the informed business community.

Highly accessible approach to game audio mixing, ideal for professional users, but also suitable as supplementary reading for students. Game Audio continues to be a massively hot topic in audio, and this title represents one of the first titles dedicated exclusively to the topic of mixing in the context of game development. Interviews with professionals and insights from the author's impressive portfolio will be inserted throughout to offer real-life examples and applications of mixing techniques.

This is the second of a pair of volumes publishing the unedited full reports of Schomburgk's travels in Guiana between 1835 and 1844, previously available only in greatly abridged and heavily edited versions. After his explorations in Guiana between 1835 and 1839 on behalf of the Royal Geographical Society, which are the subject of Volume I of The Guiana Travels of Robert Schomburgk 1835-1844, Robert Schomburgk travelled to London. He was appointed Her Majesty's Commissioner for Boundaries with the duty to survey the boundaries of British Guiana, hitherto undefined. His surveys between 1841 and 1843 consisted of three journeys. The first took him to the mouth of the Orinoco River, from where he traced the boundary south-westward to the Cuyuni River, before returning to Georgetown. The second journey involved the survey of the boundary with Brazil: first, south to the sources of the Takutu River; and then north to Mount Roraima. In the third he covered the boundary with Dutch Guiana (modern Surinam), which involved an arduous trip down the length of the Corentyne River. Schomburgk returned to London in 1844 and was knighted for his services. Volume II of The Guiana Travels contains his reports of these journeys. In abbreviated form they appeared in the Journal of the Royal Geographical Society. Here they are published in full, including the material censored by the Colonial Office, which mainly details abuses of the native population committed by Venezuelans and Brazilians. In an 'Epilogue' an account is provided of his later career. The volume also includes two appendices: a summary of the boundary disputes which arose as a result of Schomburgk's survey and a vocabulary of vernacular plant names.

This is the first of a pair of volumes publishing the full reports of Schomburgk's travels in Guiana between 1835 and 1844, previously available only in greatly abridged and heavily edited versions. Robert Schomburgk left his native Germany for North America in 1828, aged twenty-four. A year later he was in the Caribbean, where, after various business failures, he devoted himself to the investigation of natural history, especially botany. Although he had no previous contact with the Royal Geographical Society in London, the work he submitted to it was of such a quality that he was able to persuade the Society to sponsor explorations in the north-east of South America, an area for which no accurate maps and little reliable information existed. From Schomburgk's arrival in British Guiana in 1835 up to 1839, he explored much of the interior of the colony and completed the arduous overland journey to the Orinoco to connect his survey with that of Alexander von Humboldt. During these expeditions he witnessed maltreatment of Amerindians at the hand of Brazilians, and having ascertained that the boundary between Brazil and British Guiana was undefined he proposed it should be fixed so that those within the British colony would be protected from further harassment. The British Government decided to go ahead with this exercise, and Schomburgk was appointed boundary commissioner with the task of surveying the boundaries of the colony. He did this between 1841 and 1843, returning to London in 1844 to be rewarded with a knighthood for his services. During much of his subsequent career, until his death in 1865, he acted as a British consul, first in Santo Domingo and then in Bangkok.

Jacques Riviere knew how to accept art emotionally. No French critic was ever less a traditional pedagogue. Rivibre was an intelligent French writer, who knew that the summit of the intellect is to admit aff ective knowledge, instinct, and intuition. The "heart," or taste, is always superior to raw intelligence. Reviere's supple metaphors are not easily rendered into English. Th e density of his thought, the complexity of his views, the moral and spiritual fervor that vibrates in these pages, further enhances the difficulties the skilled translator must overcome. Literary criticism is often ephemeral; it has served its purpose if it stimulates discussion about the work of art under scrutiny. Not so with essays like these. Th ey demand an active reading, as do the original works themselves. Th ey do not easily yield their signifi cance. Among the critics who came into the French literary scene in the years immediately preceding and following the First World War, Jacques Riviere has been least affected by the attrition of time. His studies of Proust and Rimbaud still rank among the two or three essential works to be read on these authors. Few other critics have gone further in a sensuous perception of these authors' work and the intellectual lucidity in analyzing it. Reviere had few pretensions to profundity and a great purity of style. In an age of slogans and judgments, this volume reminds the reader of the extraordinary role of European critical thought in the twentieth century.

The original Handbook of Surface and Interface Analysis: Methods for Problem-Solving was based on the authors' firm belief that characterization and analysis of surfaces should be conducted in the context of problem solving and not be based on the capabilities of any individual technique. Now, a decade later, trends in science and technology appear to have validated their assertions. Major instrumental assets are generally funded and maintained as central facilities to help potential users make informed decisions about their appropriate use in solving analytical problem(s). Building on the popular first edition, this long-awaited second edition was motivated by the increasingly common industry view that it is more cost-effective to contract out analytical services than to maintain in-house facilities. Guided by that trend, this book focuses on developing strategic thinking for those who decide which facilities to access and where to subcontract analytical work. It covers most of the major tactical issues that are relevant at the location in which data are being produced. New Information in this Second Edition Includes: Electron-optical imaging techniques and associated analytical methods Techniques based on synchrotron sources Convenient and versatile scanning probe group methods Scanning tunneling microscopy, biocompatible materials, and nano-structured materials Assessing benefits and limitations of different methodologies, this volume provides the essential physical basis and common modes of operation for groups of techniques. Exploring methods for characterization and analysis of particular types of materials and/or their relevant applications-the text synergizes traditional and novel ideas to help readers develop a versatile and rational approach to surface and interface analysis.

Video games have become the world's largest leading cultural product. Though disputed in the past, the narrative qualities of video games have finally secured distinction in the realm of art. This is especially true for interactive games. Writing an Interactive Story will help the reader in navigating the creation process of interactive scripts, in addition to discovering behind the scenes narrative choices of renowned games, and will help you to harness your inner creativity. Guided by master interactive scriptwriters, the text presents its content in the form of a unique writing workshop. With interactive game writing, the player becomes the star of the work. Thanks to this method of storytelling, the morals of the game become resonant. This is because the weight of the narrative's choices and consequences rest fully upon the player. It's the ultimate narrative. Whether you are a video game enthusiast, student, or professional, discover how to create a more immersive personalized experience than ever before and give your players the opportunity to write their own destiny through their choices. The methods, strategies, and secrets of this new art await you. Features exclusive interviews with: David Cage - BAFTA Award for Best Story - Heavy Rain Jean-Luc Cano - BAFTA Award for Best Story - Life Is Strange Joe Penny, David Bowman - Telltale's The Wolf Among Us, The Walking Dead Benjamin Diebling - Beyond Two Souls, Detroit: Become Human Erwan Le Breton - Ubisoft Thomas Veauclin- The Council Fibre Tigre - Out There

Although best known as a disseminator of Freudian and Kleinian ideas, the author also contributed important and original material to the body of psychoanalytic literature. This volume presents some of this material and highlights the importance of the author's contribution.

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barrier may result in damage to the skin or may alter absorption. With contributions from over 40 international experts in the field of skin biology, the book presents the central role of the skin barrier to health and disease reviewing; The skin's anatomy and physiology, with focus on the stratum corneum as a barrier to foreign substances. Dermal absorption, cutaneous metabolism, and epidermal transporters. Altered barriers, racial skin types, aged skin, photoaged skin, cosmetics and skin sensitization. Modern approaches to drug delivery across the skin barrier, including liposomes, microneedle technology, active and passive transdermal delivery. Examples and case studies of chemical toxicity after topical exposures ranging from arsenic, metal working fluids, bromine, jet fuel, sulfur mustard and including the emerging area of nanomaterial penetration. Toxicology of the Skin is essential reading for drug delivery pharmacologist, formulation scientists, dermatologists, toxicologists, molecular biologists, engineers, surgeons, students and anyone interested in skin irritation and skin absorption.

Psychoanalysis is a science evidently fore-ordained to growth and expansion, and among those who have extended the scope of both theory and practice Melanie Klein holds a unique place.This book is a survey of the developments in psychoanalytical knowledge resulting from her work. Her main discoveries relate to the very early phases of mental life. She recognized that the world of unconscious feeling and impulse (which we call 'phantasy') is the effective source of all human actions and reactions, modified though they are when translated into actual external behaviour or conscious thought. Although Freud first enunciated this truth, which originates in his fundamental discovery of the unconscious mind of man, he left many problems still unsolved. These have been brought nearer to a solution through Melanie Klein's consistent awareness of the significance of unconscious phantasy. Not only students of psychoanalysis and workers in related medical fields but also practising child-psychologists and the informed lay public will find this book of absorbing interest.

Jacques Riviere knew how to accept art emotionally. No French critic was ever less a traditional pedagogue. Rivire was an intelligent French writer, who knew that the summit of the intellect is to admit aff ective knowledge, instinct, and intuition. The "heart," or taste, is always superior to raw intelligence.

Reviere's supple metaphors are not easily rendered into English. Th e density of his thought, the complexity of his views, the moral and spiritual fervor that vibrates in these pages, further enhances the difficulties the skilled translator must overcome. Literary criticism is often ephemeral; it has served its purpose if it stimulates discussion about the work of art under scrutiny. Not so with essays like these. Th ey demand an active reading, as do the original works themselves. Th ey do not easily yield their signifi cance.

Among the critics who came into the French literary scene in the years immediately preceding and following the First World War, Jacques Riviere has been least affected by the attrition of time. His studies of Proust and Rimbaud still rank among the two or three essential works to be read on these authors. Few other critics have gone further in a sensuous perception of these authors' work and the intellectual lucidity in analyzing it. Reviere had few pretensions to profundity and a great purity of style. In an age of slogans and judgments, this volume reminds the reader of the extraordinary role of European critical thought in the twentieth century.

"Jacques Riviere" (1886-1925) was a long time editor at NRF ("Nouvelle Revue Francaise")-- from 1912-1914; and after the war was ended, from 1919-1925. He wrote steadily during this period, many of his essays appearing in this volume. He caught typhoid fever and died in February 1925.

"Henri Peyre" (1901-1988) was Sterling Professor and chair of the French Department at Yale University. He was the author of numerous books including "Literature and Sincerity, Baudelaire: A Collection of Critical Essays," and "The Contemporary French Novel."

The original Handbook of Surface and Interface Analysis: Methods for Problem-Solving was based on the authors? firm belief that characterization and analysis of surfaces should be conducted in the context of problem solving and not be based on the capabilities of any individual technique. Now, a decade later, trends in science and technology appear to have validated their assertions.

Major instrumental assets are generally funded and maintained as central facilities to help potential users make informed decisions about their appropriate use in solving analytical problem(s). Building on the popular first edition, this long-awaited second edition was motivated by the increasingly common industry view that it is more cost-effective to contract out analytical services than to maintain in-house facilities. Guided by that trend, this book focuses on developing strategic thinking for those who decide which facilities to access and where to subcontract analytical work. It covers most of the major tactical issues that are relevant at the location in which data are being produced.

New Information in this Second Edition Includes:

• Electron-optical imaging techniques and associated analytical methods
• Techniques based on synchrotron sources
• Convenient and versatile scanning probe group methods
• Scanning tunneling microscopy, biocompatible materials, and nano-structured materials

Assessing benefits and limitations of different methodologies, this volume provides the essential physical basis and common modes of operation for groups of techniques. Exploring methods for characterization and analysis of particular types of materials and/or their relevant applications?the text synergizes traditional and novel ideas to help readers develop a versatile and rational approach to surface and interface analysis.

From the discovery of x-rays in 1895 through the emergence of computed tomography (CT) in the 1970s and magnetic resonance imaging (MRI) in the 1980s, non-invasive imaging has revolutionized the practice of medicine. While these technologies have thoroughly penetrated clinical practice, scientists continue to develop novel approaches that promise to push imaging into entirely new clinical realms, while addressing the issues of dose, sensitivity, or specificity that limit existing imaging approaches. Emerging Imaging Technologies in Medicine surveys a number of emerging technologies that have the promise to find routine clinical use in the near- (less than five years), mid- (five to ten years) and long-term (more than ten years) time frames. Each chapter provides a detailed discussion of the associated physics and technology, and addresses improvements in terms of dose, sensitivity, and specificity, which are limitations of current imaging approaches. In particular, the book focuses on modalities with clinical potential rather than those likely to have an impact mainly in preclinical animal imaging. The last ten years have been a period of fervent creativity and progress in imaging technology, with improvements in computational power, nanofabrication, and laser and detector technology leading to major new developments in phase-contrast imaging, photoacoustic imaging, and optical imaging.

This work presents an holistic view of the fundamental principles and practicable methods of polluted soils. A set of definitions is presented and different aspects of the evolution of pollutants and their toxicity are developed.

Highlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicology in years to come including proteomics, toxicogenomics, and metabonomics, this expertly conceived guide explores toxicological issues of particular world interest, such as toxicity of nanomaterials, military jet fuels, and genetically-modified foods.

The major objective of this handbook is to compile-in tabular form-the pharmacokinetic parameters of antimicrobial drugs used in food animals. This unique publication represents data from the FARAD (Food Animal Residue Avoidance Databank) databank, established by the authors under the auspices of the U.S.D.A. and contains significant amounts of previously unavailable information. This updated, one-of-a-kind volume even features additional data on laboratory rodents, dogs, cats, and horses in order to facilitate broader interspecies extrapolations. This easy-to-use reference is timely as well as invaluable to animal scientists, veterinarians, pharmacologists, and toxicologists who work with antimicrobials in chickens, turkeys, dairy and beef cattle, swine, goats, and sheep.

The techniques and methods that can be applied to materials characterization on the microscale are numerous and well-established. Divided into two parts, Characterization of Nanostructures provides thumbnail sketches of the most widely used techniques and methods that apply to nanostructures, and discusses typical applications to single nanoscale objects, as well as to ensembles of such objects. Section I: Techniques and Methods overviews the physical principles of the main techniques and describes those operational modes that are most relevant to nanoscale characterization. It provides sufficient technical detail so that readers and prospective users can gain an appreciation of the strengths and limitations of particular techniques. The section covers both mainstream and less commonly used techniques. Section II: Applications of Techniques to Structures of Different Dimensionalities and Functionalities deals with the methods for materials characterization of generic types of systems, using carefully chosen illustrations from the literature. Each chapter begins with a brief description of the materials and supplies a context for the methods for characterization. The volume concludes with a series of flow charts and brief descriptions of tactical issues. The authors focus on the needs of the research laboratory but also address those of quality control, industrial troubleshooting, and online analysis. Characterization of Nanostructures describes those techniques and their operational modes that are most relevant to nanoscale characterization. It is especially relevant to systems of different dimensionalities and functionalities. The book builds a bridge between generalists, who play vital roles in the post-disciplinary area of nanotechnology, and specialists, who view themselves as more in the context of the discipline.

Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products-with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell-based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.

This book covers all major areas of interest in the rapidly expanding field of in vitro methods for percutaneous absorption studies. Specific areas discussed include diffusion cell design, receptor fluid, preparation of skin, and temperature. The book covers experimental methodology, as well as the underlying principles and fundamentals that help professionals and students gain an understanding of the basis for currently used methodology.