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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Toxicology (non-medical)
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Nanotoxicology - Progress toward Nanomedicine, Second Edition (Paperback, 2nd edition)
Loot Price: R1,650
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Nanotoxicology - Progress toward Nanomedicine, Second Edition (Paperback, 2nd edition)
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Since the first publication of this book in 2007, the field of
nanoscience and nanomedicine continues to grow substantially. This
second edition, Nanotoxicology: Progress toward Nanomedicine,
enlists internationally recognized experts to document the
continuing development and rationale for the safe design of
engineered nanomaterials (ENM). This includes new improved
characterization endpoints, screening, and detection methods for in
vitro and in vivo toxicity testing. These tools also contribute
greatly to nanosafety research applied to nanomedicines. Topics
include The impacts of nanotechnology on biomedicine, including
functionalization for tissue-specific targeting, the
biointeractions of multifunctional nanoparticle-based therapy, and
the ability to control specific physicochemical properties of
nanoparticles The requirements for proper detection, measurement,
and assessment both for workplace exposure and in consumer
products-with a focus on potential health and safety implications
Predictive modeling, using quantitative nanostructure activity
relationships to predict the pharmacokinetics and biodistribution
of nanomaterials in the body Specific methodologies, imaging, and
techniques to assess nanomaterials from the manufacturing process
to nanomedicine applications Tools for assessing nanoparticle
toxicity and the limitations of detection methods for assessing
toxicity in both in vivo and in vitro systems and at the single
cell and tissue levels Toxicity of nanomaterials to specific organ
systems, cell-based targeting to tumors, and other biomedical
applications The difficulty of conducting risk assessments and the
need for addressing knowledge gaps, especially with long-term
studies A roadmap for future research The development of
nanotechnology-based products must be complemented with appropriate
validated methods to assess, monitor, manage, and reduce the
potential risks of ENM to human health and the environment. This
volume provides a cogent survey of advances in this area by a
well-respected and diverse group of international scientists.
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