Olives and Olive Oil in Health and Disease Prevention, Second Edition expands the last releases content and coverage, including new sections on materials in packaging, the Mediterranean diet, metabolic syndrome, diabetic health, generational effects, epigenetics, glycemic control, ketogenic diet, antioxidant effects, the use of olive oil in protection against skin cancer, oleuropein and ERK1/2 MAP-Kinase, oleocanthal and estrogen receptors, and oleocanthal and neurological effects. The book is a valuable resource for food and health researchers, nutritionists, dieticians, pharmacologists, public health scientists, epidemiologists, food technologists, agronomists, analytical chemists, biochemists, biologists, physicians, biotechnologists and students.

The Role of Functional Food Security in Global Health presents a collective approach to food security through the use of functional foods as a strategy to prevent under nutrition and related diseases. This approach reflects the views of the Food and Agriculture Organization of the United Nations, the World Health Organization, the World Heart Federation and the American Heart Association who advise Mediterranean, Paleolithic, plant food based diets, and European vegetarian diets for the prevention of cardiovascular disease. In addition, the book also emphasizes the inclusion of spices, herbs and millets, as well as animal foods. This book will be a great resource to the food industry as it presents the most efficient ways to use technology to manufacture slowly absorbed, micronutrient rich functional foods by blending foods that are rich in healthy nutrients.

Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual's lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances.

Nutritional Modulators of Pain in the Aging Population provides an overview on the role of foods, dietary supplements, obesity, and nutrients in the prevention and amelioration of pain in various diseases in the aging population. Headaches, fibromyalgia, joint pain, arthritis pain, back pain, and stomach pain are discussed. In addition, the potential health risks of using foods to reduce symptoms is evaluated. Each chapter reviews pain causing conditions before reviewing the role of food or exercise. Both researchers and physicians will learn about dietary approaches that may benefit or harm people with various types of pain. Chapters include current research on the actions of nutrients in pain treatment, the effects of lifestyle and exercise on pain management, and discussions of dietary supplements that provide pain relief from chronic conditions like arthritis.

Bioactive Foods in Promoting Health: Probiotics and Prebiotics brings together experts working on the different aspects of supplementation, foods, and bacterial preparations, in health promotion and disease prevention, to provide current scientific information, as well as providing a framework upon which to build clinical disease treatment studies. Since common dietary bacterial preparations are over-the-counter and readily available, this book will be useful to the growing nutrition, food science, and natural product community that will use it as a resource in identifying dietary behavioral modifications in pursuit of improved health as well as for treatment of specific disease, as it focuses on the growing body of knowledge of the role of various bacteria in reducing disease risk and disease. Probiotics are now a multi-billion-dollar, dietary supplement business which is built upon extremely little research data. In order to follow the 1994 ruling, the U.S. Food and Drug Administration with the support of Congress is currently pushing this industry to base its claims and products on scientific research. Research as shown that dietary habits need to be altered for most people whether for continued or improved good health. The conclusions and recommendations from the various chapters in this book will provide a basis for those important factors of change by industry with new uses. Animal studies and early clinical ones will lead to new uses and studies. Particularly the cutting edge experimental and clinical studies from Europe will provide novel approaches to clinical uses through their innovative new studies.

Sleep disorder is a rampant problem in the US, with over 40 million Americans currently diagnosed according to the NIH. There is a clear association between sleep disorder and a wide range of other human disorders -performance deficiencies, psychiatric illnesses, heart disease, obesity and more - but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes. This volume focuses on the interaction between sleep and these factors, with special attention being paid to the potential for neurological modulation of sleep via diet. The volume aid readers in understanding the role each of these factors plays in sleep architecture and its regulation by circadian biology and neurology.

Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion brings together experts from around the world working on the cutting edge of research on fruit, vegetables, and herbs in health promotion. Offering a timely, concise, scientific appraisal of the efficacy of key foods to prevent disease and improve the quality of life, Fruits, Vegetables, and Herbs: Bioactive Foods in Health Promotion provides valuable evidence-based conclusions and recommendations. This reference text will encourage further research on the potential benefits of fruits and vegetables in health and disease prevention, providing a basis for possible dietary modifications by the government and the public.

Genetically Modified Organisms in Food focuses on scientific evaluation of published research relating to GMO food products to assert their safety as well as potential health risks. This book is a solid reference for researchers and professionals needing information on the safety of GMO and non-GMO food production, the economic benefits of both GMO and non-GMO foods, and includes in-depth coverage of the surrounding issues of genetic engineering in foods. This is a timely publication written by a team of scientific experts in the field who present research results to help further more evidence based research to educate scientists, academics, government professionals about the safety of the global food supply.

Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive Health focuses on the ways in which food, dietary supplements, and toxic agents, including alcohol and nicotine affect the reproductive health of both women and men. Researchers in nutrition, diet, epidemiology, and endocrinology will find this comprehensive resource invaluable in their long-term goal of understanding and improving reproductive health. This book brings together a broad range of experts researching the different aspects of foods and dietary supplements that promote or detract from reproductive health. Section One contains several overview chapters on fertility, how it is assessed, and how it can be affected by different metabolic states, nutritional habits, dietary supplements, the action of antioxidants, and lifestyle choices. Sections Two and Three consider how male and female fertility are affected by obesity, metabolic syndrome, hormonal imbalance, and even bariatric surgery. Section Four explores the ways diet, nutrition, and lifestyle support or retard the success of in vitro fertilization, while Section Five explores how alcohol and other drugs of abuse lower fertility in both women and men.

The major objective of this book is to review in detail health problems occurring with significant frequency in aging adults which are proposed to be treated or ameliorated using nutriceuticals as foods and dietary supplements as well as other complementary and alternative therapies. Chapters primarily focusing on nutrients have been excluded to maintain a focus on complementary and alternative medicine (CAM).
Overview of the Book: The book is divided into three general sections as follows: I. Nutriceuticals and Botanicals in Health Promotion; (A) Specific Nutriceuticals Used in Treating Aged, (B) General Nutraceutical Approaches to Therapy with emphasis on cancer. II. Non-nutritional CAM Therapies. (A) Mind-mediated Therapies, (B) Physically Applied CAM Therapies

I. Non-Nutritional Components in Diet and Supplements, Nutriceuticals and their Role in Health Promotion in the Mature Adult.
Nutrient requirements for optimum health and function of aging physiological systems often are quite distinct from young ones. Nutriceuticals, without nutrients as foods or dietary supplements benefit the aged by both protecting nutrients from oxidative damage as well as through their direct biological activity. Recognition and understanding of the role of CAM nutriceuticals in health of the aged is being intensively researched and tested, especially due to the increases in the elderly in the general population. In developed countries, economic restrictions and physical inactivity during aging can significantly reduce food intakes, contributing to nutritional stresses and needs. Many disease entities and cancers are found with higher frequency in the aged. Cancer, trauma, or infectiousdisease can alter intakes of nutriceutical containing foods and/or requirements for various nutrients. Nutriceuticals, especially those of botanical origins have thousands of biologically active chemicals. Thus specific foods and nutriceutical supplementation may be helpful in treatment of aged adults including cancer patients. Many adults and elderly are using foods and nutriceutical supplements above the recommended daily allowance, which may not always be needed for optimal health. To some extent, treatment of these conditions with diet or nutriceutical supplements is a unique problem in the aged. In summary, increasing numbers of older adults and elderly in the population require detailed study and directed research to understand their health problems, using novel nutriceutical and CAM therapies.
II. Nutriceuticals in Disease and Cancer Therapy in Seniors.
Research continues to show that non-nutritional materials in the diet or as supplements can have important health promotion benefits. Those that are antioxidants act, in part, by protecting antioxidant vitamins. However much needs to be learned about benefits and risks of nutriceuticals which have a variety of biological activities in their own right. Therefore botanical extracts and components will be reviewed for their benefits to seniors.
III. Non-dietary Complementary and Alternative Medicine (CAM) Use and Benefits to the Elderly in Health.
The elderly are frequently using various non-traditional and often unproven CAM therapies, beyond nutritional and nutraceutical supplements. Therefore a variety of physical and psychosocial treatments will be evaluated by experts in CAM research for their benefits/risks andthe extent of scientific testing.
*Identifies the important nutritional requirements of the aging population, and how nutraceuticals and other CAM options affect those
* Addresses the many disease entities and cancers are found with higher frequency in the aged, including cancer, trauma, or infectious disease that can alter intakes of nutraceutical containing foods and/or requirements for various nutrients.
* Explores the nutritional materials botanical extracts and components that can have important health promotion benefits and risks, to ensure safe consumption
* Reviews the frequently used non-traditional and often unproven CAM therapies, beyond nutritional and nutraceutical supplements, including a variety of physical and psychosocial treatments.

Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss are devastating. There are a range of ocular defects that have either their origin in nutritional deficiencies/excess or have been shown to respond favorably to nutritional components. Featuring a new section on animal model studies where both the ocular problem and dietary remedies can be varied, there are also new chapters on dietary supplements.

Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities.

Polyphenols in Prevention and Treatment of Human Disease, Second Edition authoritatively covers evidence of the powerful health benefits of polyphenols, touching on cardiovascular disease, cancer, obesity, diabetes and osteoporosis. This collection represents the contributions of an international group of experts in polyphenol research who share their expertise in endocrinology, public health, cardiology, pharmacology, agriculture and veterinary science. Researchers from diverse backgrounds will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted insights into the mechanisms of disease. This reference fills a void in research where nutritionists and alternative therapies may be applicable.

Lifestyle and Heart Health and Disease provides a comprehensive evaluation of lifestyle factors that modify heart function and structure. It includes coverage of a wide range of lifestyle factors, including physical activity, alcohol, tobacco, drugs of abuse, nutrition and psychosocial factors. The book clearly presents the scientific evaluation of published research relating to general responses by scientists, physicians and patients, along with new research on the role of lifestyle in the prevention, amelioration and causation of cardiac remodeling and disease.

Dairy in Human Health and Disease across the Lifespan addresses the contribution of milk to the human diet and health throughout the life span. This comprehensive book is divided into three sections and presents a balanced overview of dairy's impact on nutrition from infancy to adulthood. Summaries capture the most salient points of each chapter, and the book provides coverage of dairy as a functional food in health and disease.

Health of HIV Infected People: Food, Nutrition and Lifestyle Without Antiretroviral Drugs defines the supportive roles of bioactive foods, exercise, and dietary supplements on the health of HIV infected people who do not have access to resources or those who choose not to utilize antiretroviral drugs. Approaches such as the application of traditional herbs and foods are given careful definition by experts who define the risks and benefits of such practices within this important context. Readers learn how to treat or ameliorate the effects of chronic retroviral disease using readily available, cheap foods, and dietary supplements. Ultimately, this work delivers a current, concise, scientific appraisal of the efficacy of key foods, nutrients, dietary plants, and behavioral changes in preventing and improving the quality of life of HIV infected infants and adults who are not undergoing antiretroviral therapy.

The Mediterranean Diet offers researchers and clinicians a single authoritative source which outlines many of the complex features of the Mediterranean diet: ranging from supportive evidence and epidemiological studies, to the antioxidant properties of individual components. This book embraces a holistic approach and effectively investigates the Mediterranean diet from the cell to the nutritional well-being of geographical populations. This book represents essential reading for researchers and practicing clinicians in nutrition, dietetics, endocrinology, and public health, as well as researchers, such as molecular or cellular biochemists, interested in lipids, metabolism, and obesity.

This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progress to diabetes and heart disease. The book further focuses on glucose intake and utilization in diabetes, including coverage of diabetes in the development and pathology of cardiovascular disease, risks and epidemiology of cardiovascular problems promoted by diabetes, macrovascular effects and their safety in therapy of diabetics, beta cell biology and therapy of diabetes, and nutrition to modulate diabetes.

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. "Omega-3 Fatty Acids in Brain and Neurological Health" is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons.

Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health.
The first book-length collection of original research on the connection between omega-3 fatty acids and the brainProvides a comprehensive introduction to the state of research on omega-3 fatty acids and the brain and directions for future researchA foundational collection for neuroscience, neurology, and nutrition research

"Nutrition in the Prevention and Treatment of Abdominal Obesity" focuses on the important roles that exercise, dietary changes, and foods play in promoting as well as reducing visceral fat. Nutritionists, dieticians, and healthcare providers seeking to address the abdominal obesity epidemic will use this comprehensive resource as a tool in their long-term goal of preventing chronic diseases, especially heart, vascular, and diabetic diseases.

Experts from a broad range of disciplines are involved in dealing with the consequences of excessive abdominal fat: cardiology, diabetes research, studies of lipids, endocrinology and metabolism, nutrition, obesity, and exercise physiology. They have contributed chapters that define a range of dietary approaches to reducing risk and associated chronic diseases. They begin by defining visceral obesity and its major outcomes; they also discuss the importance and the challenges of dietary approaches to reduce abdominal obesity, as compared to clinical approaches, with major costs and risks.
Offers detailed, well-documented reviews outlining the various dietary approaches to visceral obesity with their benefits and failuresIncludes chapters on types of foods, exercise, and supplements in reducing obesity and its chronic clinical companions, especially diabetes and cardiovascular diseaseHelps nutritionists, dieticians, and healthcare providers approach patients in making decision about nutritional therapies and clinical treatments for abdominal obesity, from an evidence-based perspective

Nutrition and Diet in Menopause is a single comprehensive source that will provide readers with an understanding of menopause. Holistic in its approach, this volume is divided into five sections covering psychological, endocrine and lifestyle factors, metabolism and physiology, bone and nutrition, cancer and nutrition, cardiovascular factors and dietary supplements in menopause. In-depth chapters review the potential long term consequences of menopause on the overall health of women, not only at the physical level including hot flushes (flashes) , alterations to the genitourinary system, skin changes, decreased cardiovascular functions, hypertension, headache, back pain, and constipation. Written by international leaders and trendsetters, Nutrition and Diet in Menopause is essential reading for endocrinologists, cardiologists, nutritionists and all health care professionals who are interested in women's health.

The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.

Holistic in its coverage Written by International experts Well illustrated throughout and "readable" Each chapter is "self contained" Wide coverage In-depth analysis and discourse onsistent style and level of coverage from novice to expert A "one-stop-shopping" approach to everything you need to know about dietary components including botanical products in immune regulation and disease prevention Dietary Components and Immune Function focuses on immune modulation, immune mediated disease resistance, immune changes due to AIDS, immune modulated cancer therapy, and autoimmune diseases as modified by dietary supplement, bioactive foods and supplements. The potential value of such approaches in maintaining wellness and preventing disease are addressed by examining their effects in vitro and in vivo on innate and adaptive immune responses. Emerging fields of science and important discoveries relating to early stages of new nutriceuticals in cancer prevention, prior to clinical trials are also covered. This volume represents a single source of material related to nutriceuticals and their constituents as they relate to cancer therapy and prevention. As such the book will be essential reading for nutritionists, pharmacologists, health care professionals, research scientists, cancer workers, pathologists, molecular or cellular biochemists, physicians, general practitioners as well as those interested in diet and nutrition in disease resistance via immune regulation.

Chronic alcohol use is associated with heart, liver, brain, and other organ pathology. Alcohol is a drug of abuse and a caloric food and it causes poor intake and absorption of nutrients, thus playing a major role in many aspects of clinical consequences. Alcohol use lowers consumption of fruit and vegetables, lowers tissue nutrients, and, in some cases, requires nutritional therapy by clinicians."Alcohol, Nutrition, and Health Consequences"will help the clinician define the causes and types of nutritional changes due to alcohol use and also explain how nutrition can be used to ameliorate its consequences. Chapters present the application of current nutritional knowledge by physicians and dietitians. Specific areas involving alcohol-related damage due to nutritional changes are reviewed, including heart disease, obesity, digestive tract cancers, lactation, brain function, and liver disease. In addition, alcohol's effects on absorption of minerals and nutrients, a key role in causing damage are treated. The importance of diet in modifying alcohol and its metabolite damage is also explained.

"Alcohol, Nutrition, and Health Consequences"is essential reading for alcohol therapists and researchers as well as primary care physicians and dietitians and is an easy reference to help the clinician, student, and dietitian comprehend the complex changes caused by direct and indirect effects of ethanol at the cellular level via its nutritional modification. "