Encyclopedia of Sensors and Biosensors, Four Volume Set provides unique foundational level information on the rapidly growing sensor community. The book covers innovations in materials, designs, devices and software that find their way into new types of sensors. Sections include over 1000 color images, including representations of sensor design, sensor manufacturing, and assessments of sensor performance. In addition, applications of sensors in healthcare, food safety, environmental engineering and other fields are discussed, making this a truly interdisciplinary work. The book is structured using a logical and thematic approach, with chapters taking a balanced viewpoint, listing both advantages and disadvantages. Perfect for those learning their trade in both academia and industry, this vital reference work will serve many groups, including chemists, engineers, biological scientists, clinicians, and industrial researchers.

Enzymes as Sensors, Volume 589, the latest release in the Methods in Enzymology series, covers a variety of topics, including advances in genetically coded fluorescent sensors, enzymes as sensors, and bioapplications of electrochemical sensors and biosensors. Users will find a comprehensive discussion of timely topics that presents a micro-level delivery of specific content related to the study of enzymes in sensors. New to this edition are highly specialized chapters on integrated strategies for gaining a systems level view of dynamic signaling networks, sensitive protein detection and quantification in paper-based microfluidics for point-of-care, and microneedle enzyme sensor arrays for continuous in vivo monitoring. This state-of-the-art series is ideal for those interested in the latest information on enzymology, with this edition focusing on sensors and their role in enzymes.

Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack of knowledge of the best methods for using label-free assays to screen for biologically active molecules and accurately and precisely characterize molecular recognition events. This book reviews both established and newer label-free techniques and is intended to give both the expert user and the general reader interested in the technologies and applications behind label-free an insight into the field from expert opinion leaders and practitioners of the technologies. Most importantly, chapters contain worked examples from leaders in the field that take the reader through the basics of experimental design, setup, assay development, and data analysis.

Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack of knowledge of the best methods for using label-free assays to screen for biologically active molecules and accurately and precisely characterize molecular recognition events. This book reviews both established and newer label-free techniques and is intended to give both the expert user and the general reader interested in the technologies and applications behind label-free an insight into the field from expert opinion leaders and practitioners of the technologies. Most importantly, chapters contain worked examples from leaders in the field that take the reader through the basics of experimental design, setup, assay development, and data analysis.

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing paradigms and biomimetic artifacts for chemical sensing. The implications of these findings are relevant to a wide audience, including researchers in artifical olfaction, neuroscientists, physiologists, and scientists working with chemical sensors. Developing neuromorphic olfaction from conceptual points of view to practical applications, this cross-disciplinary book examines: The biological components of vertebrate and invertebrate chemical sensing systems The early coding pathways in the biological olfactory system, showing how nonspecific receptor populations may have significant advantages in encoding odor intensity as well as odor identity The redundancy and the massive convergence of the olfactory receptor neurons to the olfactory bulb A neuromorphic approach to artificial olfaction in robots Reactive and cognitive search strategies for olfactory robots The implementation of a computational model of the mammalian olfactory system The book's primary focus is on translating aspects of olfaction into computationally practical algorithms. These algorithms can help us understand the underlying behavior of the chemical senses in biological systems. They can also be translated into practical applications, such as robotic navigation and systems for uniquely detecting chemical species in a complex background.

This monograph focuses on the design, implementation and characterization of a concurrent dual band RF sensor for non-invasive detection of human vital signs. Exclusive title on multiband short range sensors and their biomedical applications, offers detailed analysis of subsystems based on fabricated and measured prototypes and verifies and discusses the system in the real-time environment. Discusses the practical difficulties of the design process and offers case studies based on the design.

Shaped by Quantum Theory, Technology, and the Genomics Revolution The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The first volume, Fundamentals, Devices, and Techniques, focuses on the fundamentals of biophotonics, optical techniques, and devices. Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies. What's New in This Edition: A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of

Discussing the role biosensors play in detecting and monitoring environmental substances, Biosensors and Environmental Health provides key facts that can be applied to other areas of health and disease and a "mini-dictionary" of key terms and summary points. It covers personal toxicity testing, soil and risk assessment, pesticide, insecticides, parasites, nitrate, endocrine disruptors, heavy metals, food contamination, whole cell bioreporters, bacterial biosensors, antibody-based biosensors, enzymatic, amperometric and electrochemical aspects, quorum sensing, DNA-biosensors, cantilever biosensors, bioluminescence and other methods and applications. The contributors are leading authorities and the book is essential reading for environmental scientists, toxicologists, medical doctors, health care professionals, pathologists, biologists, biochemists, chemists and physicists, general practitioners as well as those interested in disease and sciences in general.

This monograph focuses on the design, implementation and characterization of a concurrent dual band RF sensor for non-invasive detection of human vital signs. Exclusive title on multiband short range sensors and their biomedical applications, offers detailed analysis of subsystems based on fabricated and measured prototypes and verifies and discusses the system in the real-time environment. Discusses the practical difficulties of the design process and offers case studies based on the design.

Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing paradigms and biomimetic artifacts for chemical sensing. The implications of these findings are relevant to a wide audience, including researchers in artifical olfaction, neuroscientists, physiologists, and scientists working with chemical sensors. Developing neuromorphic olfaction from conceptual points of view to practical applications, this cross-disciplinary book examines: The biological components of vertebrate and invertebrate chemical sensing systems The early coding pathways in the biological olfactory system, showing how nonspecific receptor populations may have significant advantages in encoding odor intensity as well as odor identity The redundancy and the massive convergence of the olfactory receptor neurons to the olfactory bulb A neuromorphic approach to artificial olfaction in robots Reactive and cognitive search strategies for olfactory robots The implementation of a computational model of the mammalian olfactory system The book's primary focus is on translating aspects of olfaction into computationally practical algorithms. These algorithms can help us understand the underlying behavior of the chemical senses in biological systems. They can also be translated into practical applications, such as robotic navigation and systems for uniquely detecting chemical species in a complex background.

A thorough guide to the fundamental development of linear piezoelectricity for vibrations Vibrations of Linear Piezostructures is an introductory text that offers a concise examination of the general theory of vibrations of linear piezostructures. This important book brings together in one comprehensive volume the most current information on the theory for modeling and analysis of piezostructures. The authors explore the fundamental principles of piezostructures, review the relevant mathematics, continuum mechanics and elasticity, and continuum electrodynamics as they are applied to electromechanical piezostructures, and include the work that pertains to linear constitutive laws of piezoelectricity. The book addresses modeling of linear piezostructures via Newton's approach and Variational Methods. In addition, the authors explore the weak and strong forms of the equations of motion, Galerkin approximation methods for the weak form, Fourier or modal methods, and finite element methods. This important book: Covers the fundamental developments to vibrational theory for linear piezostructures Provides an introduction to continuum mechanics, elasticity, electrodynamics, variational calculus, and applied mathematics Offers in-depth coverage of Newton's formulation of the equations of motion of vibrations of piezo-structures Discusses the variational methods for generation of equations of motion of piezo-structures Written for students, professionals, and researchers in the field, Vibrations of Linear Piezostructures is an up-to-date volume to the fundamental development of linear piezoelectricity for vibrations from initial development to fully modeled systems using various methods.

Based on the success of the first edition, this second edition continues to build upon fundamental principles of biosensor design and incorporates recent advances in intelligent materials and novel fabrication techniques for a broad range of real world applications. The book provides a multi-disciplinary focus to capture the ever-expanding field of biosensors. Smart Biosensor Technology, Second Edition includes contributions from leading specialists in a wide variety of fields with a common focus on smart biosensor design. With 21 chapters organized in five parts, this compendium covers the fundamentals of smart biosensor technology, important issues related to material design and selection, principles of biosensor design and fabrication, advances in bioelectronics, and a look at specific applications related to pathogen detection, toxicity monitoring, microfluidics and healthcare. Features Provides a solid background in the underlying principles of biosensor design and breakthrough technologies for creating more intelligent biosensors Focusses on material design and selection including cutting-edge developments in carbon nanotubes, polymer nanowires, and porous silicon Examines machine learning and introduces concepts such as DNA-based molecular computing for smart biosensor function Explores the principles of bioelectronics and nerve cell microelectrode arrays for creating novel transducers and physiological biosensors Devotes several chapters to biosensors developed to detect and monitor a variety of toxins and pathogens Offers expert opinions on the future directions, challenges and opportunities in the field

Presents a comprehensive description of the theory and practical implementation of Doppler radar-based physiological monitoring This book includes an overview of current physiological monitoring techniques and explains the fundamental technology used in remote non-contact monitoring methods. Basic radio wave propagation and radar principles are introduced along with the fundamentals of physiological motion and measurement. Specific design and implementation considerations for physiological monitoring radar systems are then discussed in detail. The authors address current research and commercial development of Doppler radar based physiological monitoring for healthcare and other applications. * Explains pros and cons of different Doppler radar architectures, including CW, FMCW, and pulsed Doppler radar * Discusses nonlinear demodulation methods, explaining dc offset, dc information, center tracking, and demodulation enabled by dc cancellation * Reviews advanced system architectures that address issues of dc offset, spectrum folding, motion interference, and range resolution * Covers Doppler radar physiological measurements demonstrated to date, from basic cardiopulmonary rate extractions to more involved volume assessments Doppler Radar Physiological Sensing serves as a fundamental reference for radar, biomedical, and microwave engineers as well as healthcare professionals interested in remote physiological monitoring methods. Olga Boric-Lubecke, PhD, is a Professor of Electrical Engineering at the University of Hawaii at Manoa, and an IEEE Fellow. She is widely recognized as a pioneer and leader in microwave radar technologies for non-contact cardiopulmonary monitoring, and in the design of integrated circuits for biomedical applications. Victor M. Lubecke, PhD, is a Professor of Electrical Engineering at the University of Hawaii at Manoa. He is an emeritus IEEE Distinguished Microwave Lecturer and has over 25 years of experience in research and development of devices and methods for radio-based remote sensing systems. Amy Droitcour, PhD, has spent ten years developing radar-based vital signs measurement technology through her dissertation research and leading product development as CTO of Kai Medical. She currently serves as Senior Vice President of R&D at Wave 80 Biosciences. Byung-Kwon-Park, PhD, is a senior research engineer at the Mechatronics R&D Center in Korea. Aditya Singh, PhD, is currently a postdoctoral researcher at the University of Hawaii Neuroscience and MRI research Program.

Optical Fiber Biosensors: Device Platforms, Biorecognition, Applications provides a comprehensive overview of the field of fiber optic sensors using an interdisciplinary approach that covers the fabrication of sensing devices and optical hardware, the functionalization to perform selective biorecognition, and the main applications of biosensors, with a present and a future outlook. Chapters discuss the principles of light propagation and the sensing devices suitable to perform biosensing with optical fibers, the process to functionalize the previous devices to selective biosensing, and applications in cells, small molecules, biomarkers and protein sensing, with a birds eye view on the most important results. This book provides a coherent picture of fiber optic biosensors, from the start (the device) to the end (the application), explaining in simple terms what is the whole process for development of a biosensor. The book also contains practical material (e.g. commercial instruments, fabrication instructions, medical standards for biocompatibility) that cannot be easily found elsewhere, and this is very useful for researchers to plan their development and build their labs.

An important guide that reviews the basics of magnetic biosensor modeling and simulation Magnetic Sensors for Biomedical Applications offers a comprehensive review of magnetic biosensor modelling and simulation. The authors--noted experts on the topic--explore the model's strengths and weaknesses and discuss the competencies of different modelling software, including homemade and commercial (for example Multi-physics modelling software). The section on sensor materials examines promising materials whose properties have been used for sensing action and predicts future smart-materials that have the potential for sensing application. Next, the authors present classifications of sensors that are divided into different sub-types. They describe their working and highlight important applications that reveal the benefits and drawbacks of relevant designs. The book also contains information on the most recent developments in the field of each sensor type. This important book: Provides an even treatment of the major foundations of magnetic biosensors Presents problem solution methods such as analytical and numerical Explains how solution methods complement each other, and offers information on their materials, design, computer aided modelling and simulation, optimization, and device fabrication Describes modeling work challenges and solutions Written for students in electrical and electronics engineering, physics, chemistry, biomedical engineering, and biology, Magnetic Sensors for Biomedical Applications offers a guide to the principles of biomagnetic sensors, recent developments, and reveals the impact of sensor modelling and simulation on magnetic sensors.

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems.

In this second volume of a sub-series dedicated to regional activities, eminent authorities form China in the field of biosensors provide an up-to-date overview of their laboratory's contribution, summarizing the primary research as it has appeared, possibly scattered, in the journal and conference literature and reflecting on their findings. This produces an innovative synthesis of such smaller research efforts into an overall perspective on the topic, which is difficult for the reader to glean from the multifarious original publications often available only in Chinese. There is latitude for the inclusion of detail that may have been excised from the original publication and for speculation on future possibilities. The net result is intense, yet highly readable accounts of the state of the art at this leading edge of analytical technology in this key region of the world.
This is the first book in the English language summarizing biosensor and bioelectronics efforts in China.

Chemical sensors and biosensors are among the fastest growing of analytical techniques. This text provides an up-to-the-minute overview of a wide range of sensing systems, discussing the elements of different transducers used in sensors and the selective elements that are employed. The style is relatively non-mathematical and informal in approach.

Key features and subjects covered include the following:

• Sensors based on both electrochemical and photometric transducers
• Mass-sensitive sensors
• Thermal-sensitive sensors
• Performance factors for sensors
• Examples of applications
• Detailed case studies of five selected sensors
• 30 discussion questions with worked examples and 80 self-assessment questions
• 140 explanatory diagrams
• An extensive bibliography

The book's approach is ideal for students at BTEC (HND and HNC) level, as well as for BSc degree and postgraduate students of analytical and physical chemistry. Chemical Sensors and Biosensors will, in addition, be invaluable to all those concerned with the environmental and biomedical applications of such systems

Immunosensors are widely used and are particularly important for fast diagnosis of diseases in remote environments as well as point-of-care devices. In this book, expert scientists are covering a selection of high quality representative examples from the past five years explaining how this area has developed. It is a compilation of recent advances in several areas of immunosensors for multiple target analysis using laboratory based or point-of-care set-up, for example graphene-, ISFET- and nanostructure-based immunosensors, electrochemical magneto immunosensors and nanoimprinted immunosensors. Filling a gap in the literature, it showcases the multidisciplinary, innovative developments in this highly important area and provides pointers towards commercialisation. Delivering a single, comprehensive work, it appeals to graduate students and professional researchers across academia and industry.

Chemical, Gas, and Biosensors for the Internet of Things and Related Applications brings together the fields of sensors and analytical chemistry, devices and machines, and network and information technology. This thorough resource enables researchers to effectively collaborate to advance this rapidly expanding, interdisciplinary area of study. As innovative developments in the Internet of Things (IoT) continue to open new possibilities for quality of life improvement, sensor technology must keep pace, Drs. Mitsubayashi, Niwa and Ueno have brought together the top minds in their respective fields to provide the latest information on the numerous uses of this technology. Topics covered include life-assist systems, network monitoring with portable environmental sensors, wireless livestock health monitoring, point-of-care health monitoring, organic electronics and bio-batteries, and more.

Gain the basic knowledge you need to utilize modern technologies for biosensors—quickly and efficiently

Biosensors have become virtually indispensable components in the analytical scientist's toolkit. Increasingly, researchers are called upon to design and adapt them for customized applications. Yet, surprisingly, most young scientists graduate without having acquired an integrated working knowledge of the cross-disciplinary principles underlying biosensing strategies. This book was prepared to fill that critical educational gap.

Introduction to Bioanalytical Sensors presents to readers a broad view of scientific concepts and principles informing the design and use of biosensing devices and systems. While it offers an integrated presentation of foundational information from an array of related scientific disciplines, the emphasis throughout is on applications rather than theory. Only as much basic science is covered as is necessary for an analytical scientist to use or customize biosensing devices for fulfilling experimental objectives. Major topics covered include:

• Biosensors and bioanalytical challenges
• Designing for performance
• Developing bioselective layers
• Fundamentals of electroanalytical sensors
• Optically based energy transduction
• Thermal and acoustic-wave transduction

Introduction to Bioanalytical Sensors, written as a self-teaching guide, assumes that readers have only a bachelor's degree in chemistry or a related field utilizing analytical and physical chemistry, and biochemistry.

Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers. Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems-arming readers with an application-based reference that enriches the implementation of the most advanced technologies in the field.

Fluorescent chemosensors have been widely applied in many diverse fields such as biology, physiology, pharmacology, and environmental sciences. The interdisciplinary nature of chemosensor research has continued to grow over the last 25 years to meet the increasing needs of monitoring our environment and health. More recently, a large range of fluorescent chemosensors have been established for the detection of biologically and/or environmentally important species, and are increasingly being used to solve biological problems. The use of these molecules as imaging probes to diagnose and treat disease is gaining momentum with clear future applications. This book will bring together world-leading experts to describe the current state of play in the field and introduce the cutting-edge research and possible future directions into fluorescent chemosensors design. Chapters focus on the basic principles involved in the design of chemosensors for specific analytes, problems, and challenges in the field. Concentrating on advanced techniques and methods, the book will be of use for academics and researchers across a number of disciplines, with international appeal.

"Biological Identification" provides a detailed review of, and potential future developments in, the technologies available to counter the threats to life and health posed by natural pathogens, toxins, and bioterrorism agents. Biological identification systems must be fast, accurate, reliable, and easy to use. It is also important to employ the most suitable technology in dealing with any particular threat. This book covers the fundamentals of these vital systems and lays out possible advances in the technology.

Part one covers the essentials of DNA and RNA sequencing for the identification of pathogens, including next generation sequencing (NGS), polymerase chain reaction (PCR) methods, isothermal amplification, and bead array technologies. Part two addresses a variety of approaches to making identification systems portable, tackling the special requirements of smaller, mobile systems in fluid movement, power usage, and sample preparation. Part three focuses on a range of optical methods and their advantages. Finally, part four describes a unique approach to sample preparation and a promising approach to identification using mass spectroscopy.

"Biological Identification" is a useful resource for academics and engineers involved in the microelectronics and sensors industry, and for companies, medical organizations and military bodies looking for biodetection solutions.
Covers DNA sequencing of pathogens, lab-on-chip, and portable systems for biodetection and analysisProvides an in-depth description of optical systems and explores sample preparation and mass spectrometry-based biological analysis

Nanomaterials Design for Sensing Applications examines chemosensors, beginning with molecules that are able to respond to certain stimuli and then showing their assembly and incorporation into sensing materials. The mechanisms of their action for the detection of ions, specific molecules and biostructures, are also covered. A major theme is the affordability of sensors, with particular attention paid to inexpensive and reliable colorimetric sensors that can be read by the naked eye. The book also delves into the development of sensors that utilize existing RFID infrastructure and introduces a novel strategy for the development of self-healing sensing platforms. This book will help readers develop a better understanding of the types of materials used for sensing at the nano level, while also providing an insightful overview on recent advances in this important area.