This book takes Complexity Theory and applies it to medicine where it has previously made little ground. It provides new hypotheses for multiple common but misunderstood diseases. Doctors in particular will understand that many diseases have remained unsolved due to a linear approach to what are complex biological systems, and failure to understand and apply Complexity Theory. Therefore, many common conditions have no known cause and consequently treatments are either ineffectual or non-existant, when many of these diseases are in fact preventable. There is growing interest in non-linear science, dynamic systems, chaos and complexity theory. This trend has directly involved other sciences, including biology, but has been little touched on by medicine. Readers of this book will: * Understand the difference between Linear Science and Complexity Theory, and how medicine has failed to apply the latter. * Recognise the advantages of using this understanding to generate realistic hypotheses for cause of disease. * Read how hypotheses so generated have been formulated for a number of common diseases.

These proceedings from the 2013 symposium on "Chaos, complexity and leadership" reflect current research results from all branches of Chaos, Complex Systems and their applications in Management. Included are the diverse results in the fields of applied nonlinear methods, modeling of data and simulations, as well as theoretical achievements of Chaos and Complex Systems. Also highlighted are Leadership and Management applications of Chaos and Complexity Theory.

This monograph introduces a newly developed robust-control design technique for a wide class of continuous-time dynamical systems called the "attractive ellipsoid method." Along with a coherent introduction to the proposed control design and related topics, the monograph studies nonlinear affine control systems in the presence of uncertainty and presents a constructive and easily implementable control strategy that guarantees certain stability properties. The authors discuss linear-style feedback control synthesis in the context of the above-mentioned systems. The development and physical implementation of high-performance robust-feedback controllers that work in the absence of complete information is addressed, with numerous examples to illustrate how to apply the attractive ellipsoid method to mechanical and electromechanical systems. While theorems are proved systematically, the emphasis is on understanding and applying the theory to real-world situations. Attractive Ellipsoids in Robust Control will appeal to undergraduate and graduate students with a background in modern systems theory as well as researchers in the fields of control engineering and applied mathematics.

The proposed book presents recent breakthroughs for the control of distributed parameter systems and follows on from a workshop devoted to this topic. It introduces new and unified visions of the challenging control problems raised by distributed parameter systems. The book collects contributions written by prominent international experts in the control community, addressing a wide variety of topics. It spans the full range from theoretical research to practical implementation and follows three traverse axes: emerging ideas in terms of control strategies (energy shaping, prediction-based control, numerical control, input saturation), theoretical concepts for interconnected systems (with potential non-linear actuation dynamics), advanced applications (cable-operated elevators, traffic networks), and numerical aspects. Cutting-edge experts in the field contributed in this volume, making it a valuable reference source for control practitioners, graduate students, and scientists researching practical and theoretical solutions to the challenging problems raised by distributed parameter systems.

This book presents the fundamental theory for non-standard diffusion problems in movement ecology. Levy processes and anomalous diffusion have shown to be both powerful and useful tools for qualitatively and quantitatively describing a wide variety of spatial population ecological phenomena and dynamics, such as invasion fronts and search strategies. Adopting a self-contained, textbook-style approach, the authors provide the elements of statistical physics and stochastic processes on which the modeling of movement ecology is based and systematically introduce the physical characterization of ecological processes at the microscopic, mesoscopic and macroscopic levels. The explicit definition of these levels and their interrelations is particularly suitable to coping with the broad spectrum of space and time scales involved in bio-ecological problems. Including numerous exercises (with solutions), this text is aimed at graduate students and newcomers in this field at the interface of theoretical ecology, mathematical biology and physics.

Summary Explains in easy-to-understand terms what executives and senior managers need to know and do about the ever-changing cyber threat landscape. Gives strategic, business-focused guidance and advice relevant to C-suite executives. Provides an effective and efficient framework for managing cyber governance, risk and compliance. Explains what is required to implement an effective cyber security strategy. Description With high-profile cyber attacks, data breaches and fines for GDPR (General Data Protection Regulation) non-compliance hitting the headlines daily, businesses must protect themselves and their reputations, while reassuring stakeholders they take cyber security seriously. Cyber attacks are becoming more sophisticated and prevalent, and the cost of data breaches is soaring. In addition, new regulations and reporting requirements make cyber security a critical business issue. Board members and senior management must understand the threat landscape and the strategies they can employ to establish, implement and maintain effective cyber resilience throughout their organisation. How Cyber Security Can Protect your Business - A guide for all stakeholders provides an effective and efficient framework for managing cyber governance, risk and compliance, which organisations can adapt to meet their own risk appetite and synchronise with their people, processes and technology. It explains what is meant by governance, risk and compliance, how it applies to cyber security and what is required to implement an effective cyber security strategy. The pocket guide: Gives readers a greater understanding of cyber governance, risk and compliance; Explains what executives, senior managers and their advisors need to know and do about the ever-changing cyber threat landscape; Provides context as to why stakeholders need to be aware of and in control of their organisation's cyber risk management and cyber incident response; Gives guidance on building an appropriate and efficient governance framework that enables organisations to demonstrate their cyber approach in a non-technical, strategic, business-focused way; Details an overview process to enable risk assessment, assess existing defence mitigations and provide a framework for developing suitable controls; and Includes a checklist to help readers focus on their higher-priority cyber areas. Suitable for all managers and executives, this pocket guide will be of interest to non-cyber specialists, including non-executive directors, who may be required to review cyber arrangements. For cyber specialists, it provides an approach for explaining cyber issues in non-jargonistic, business-based language. Kick-start your journey to becoming cyber secure - buy this pocket guide today!

The book provides a systematic and in-depth introduction to distributed event-triggered cooperative control for multi-agent systems from a theoretical perspective, which will be of particular interest to the readers. The included major research topics include: a unified design and analysis framework for centralized, clustered and distributed event-triggered schemes; fully distributed design for event/self-triggered schemes; resilient event-triggered control under malicious attacks; and various methods to aovid Zeno behavior. The comprehensive and systematic treatment of event-triggered communication and control in multi-agent system is one of the major features of the book, which is particularly suited for readers who are interested in learning principles and methods to deal with communication constraints in multi-agent systems and to design energy-saving control protocols. The book can benefit researchers, engineers, and graduate students in the fields of complex networks, smart grids, applied mathematics, electrical and electronic engineering, and computer engineering, etc.

The proceedings of the 4th Stability and Control Processes Conference are focused on modern applied mathematics, stability theory, and control processes. The conference was held in recognition of the 90th birthday of Professor Vladimir Ivanovich Zubov (1930-2000). This selection of papers reflects the wide-ranging nature of V. I. Zubov's work, which included contributions to the development of the qualitative theory of differential equations, the theory of rigid body motion, optimal control theory, and the theory of electromagnetic fields. It helps to advance many aspects of the theory of control systems, including questions of motion stability, nonlinear oscillations in control systems, navigation and reliability of control devices, vibration theory, and quantization of orbits. The disparate applications covered by the book - in mechanical systems, game theory, solid-state physics, socio-economic systems and medical and biological systems, control automata and navigation - are developments from Professor Zubov's in-depth studies on the theory of stability of motion, the theory of automatic control and the theory of the motions of optimal processes. Stability and Control Processes presents research continuing the legacy of V. I. Zubov and updates it with sections focused on intelligence-based control. These proceedings will be of interest to academics, professionals working in industry and researchers alike.

This monograph explores the design of controllers that suppress oscillations and instabilities in congested traffic flow using PDE backstepping methods. The first part of the text is concerned with basic backstepping control of freeway traffic using the Aw-Rascle-Zhang (ARZ) second-order PDE model. It begins by illustrating a basic control problem - suppressing traffic with stop-and-go oscillations downstream of ramp metering - before turning to the more challenging case for traffic upstream of ramp metering. The authors demonstrate how to design state observers for the purpose of stabilization using output-feedback control. Experimental traffic data are then used to calibrate the ARZ model and validate the boundary observer design. Because large uncertainties may arise in traffic models, adaptive control and reinforcement learning methods are also explored in detail. Part II then extends the conventional ARZ model utilized until this point in order to address more complex traffic conditions: multi-lane traffic, multi-class traffic, networks of freeway segments, and driver use of routing apps. The final chapters demonstrate the use of the Lighthill-Whitham-Richards (LWR) first-order PDE model to regulate congestion in traffic flows and to optimize flow through a bottleneck. In order to make the text self-contained, an introduction to the PDE backstepping method for systems of coupled first-order hyperbolic PDEs is included. Traffic Congestion Control by PDE Backstepping is ideal for control theorists working on control of systems modeled by PDEs and for traffic engineers and applied scientists working on unsteady traffic flows. It will also be a valuable resource for researchers interested in boundary control of coupled systems of first-order hyperbolic PDEs.

Maximizing reader insights into the roles of intelligent agents in networks, air traffic and emergency departments, this volume focuses on congestion in systems where safety and security are at stake, devoting special attention to applying game theoretic analysis of congestion to: protocols in wired and wireless networks; power generation, air transportation and emergency department overcrowding. Reviewing exhaustively the key recent research into the interactions between game theory, excessive crowding, and safety and security elements, this book establishes a new research angle by illustrating linkages between the different research approaches and serves to lay the foundations for subsequent analysis. Congestion (excessive crowding) is defined in this work as all kinds of flows; e.g., road/sea/air traffic, people, data, information, water, electricity, and organisms. Analysing systems where congestion occurs - which may be in parallel, series, interlinked, or interdependent, with flows one way or both ways - this book puts forward new congestion models, breaking new ground by introducing game theory and safety/security into proceedings. Addressing the multiple actors who may hold different concerns regarding system reliability; e.g. one or several terrorists, a government, various local or regional government agencies, or others with stakes for or against system reliability, this book describes how governments and authorities may have the tools to handle congestion, but that these tools need to be improved whilst additionally ensuring safety and security against various threats. This game-theoretic analysis sets this two volume book apart from the current congestion literature and ensures that the work will be of use to postgraduates, researchers, 3rd/4th-year undergraduates, policy makers, and practitioners.

The past decade has seen tremendous interest in the production and refinement of unmanned aerial vehicles, both fixed-wing, such as airplanes and rotary-wing, such as helicopters and vertical takeoff and landing vehicles. This book provides a diversified survey of research and development on small and miniature unmanned aerial vehicles of both fixed and rotary wing designs. From historical background to proposed new applications, this is the most comprehensive reference yet.

Decomposition methods aim to reduce large-scale problems to simpler problems. This monograph presents selected aspects of the dimension-reduction problem. Exact and approximate aggregations of multidimensional systems are developed and from a known model of input-output balance, aggregation methods are categorized. The issues of loss of accuracy, recovery of original variables (disaggregation), and compatibility conditions are analyzed in detail. The method of iterative aggregation in large-scale problems is studied. For fixed weights, successively simpler aggregated problems are solved and the convergence of their solution to that of the original problem is analyzed. An introduction to block integer programming is considered. Duality theory, which is widely used in continuous block programming, does not work for the integer problem. A survey of alternative methods is presented and special attention is given to combined methods of decomposition. Block problems in which the coupling variables do not enter the binding constraints are studied. These models are worthwhile because they permit a decomposition with respect to primal and dual variables by two-level algorithms instead of three-level algorithms. Audience: This book is addressed to specialists in operations research, optimization, and optimal control.

This book contains all refereed papers that were accepted to the sixth edition of the " Complex Systems Design & Management Paris " (CSD&M Paris 2015) international conference which took place in Paris (France) on November 23-25, 2015.These proceedings cover the most recent trends in the emerging field of complex systems sciences & practices from an industrial and academic perspective, including the main industrial domains (aeronautics & aerospace, defense & security, electronics & robotics, energy & environment, health & welfare, software & e-services, transportation), scientific & technical topics (systems fundamentals, systems architecture & engineering, systems metrics & quality, systems modeling tools) and systems types (artificial ecosystems, embedded systems, software & information systems, systems of systems, transportation systems).The CSD&M Paris 2015 conference is organized under the guidance of the CESAMES non-profit organization, address: CESAMES, 8 rue de Hanovre, 75002 Paris, France.

Computing Tools for Modeling, Optimization and Simulation reflects the need for preserving the marriage between operations research and computing in order to create more efficient and powerful software tools in the years ahead. The 17 papers included in this volume were carefully selected to cover a wide range of topics related to the interface between operations research and computer science. The volume includes the now perennial applications of rnetaheuristics (such as genetic algorithms, scatter search, and tabu search) as well as research on global optimization, knowledge management, software rnaintainability and object-oriented modeling. These topics reflect the complexity and variety of the problems that current and future software tools must be capable of tackling. The OR/CS interface is frequently at the core of successful applications and the development of new methodologies, making the research in this book a relevant reference in the future. The editors' goal for this book has been to increase the interest in the interface of computer science and operations research. Both researchers and practitioners will benefit from this book. The tutorial papers may spark the interest of practitioners for developing and applying new techniques to complex problems. In addition, the book includes papers that explore new angles of well-established methods for problems in the area of nonlinear optimization and mixed integer programming, which seasoned researchers in these fields may find fascinating.

From the reviews:

"This book [...] gives a comprehensive overview of the implementation of OFDM systems. [ ] For those who study or work on broadband communication in a wireless multipath environment, this book is a useful and easy-to-read reference. [...]"
(Zongsen Wu, Shaowen Song and Tianying Ji, Physics and Computing Dept., Wilfrid Laurier University, ON)

System Theory: Modeling, Analysis and Control contains thirty-three scientific papers covering a wide range of topics in systems and control. These papers have been contributed to a symposium organized to celebrate Sanjoy K. Mitter's 65th birthday. The following research topics are addressed: distributed parameter systems, stochastic control, filtering and estimation, optimization and optimal control, image processing and vision, hierarchical systems and hybrid control, nonlinear systems, and linear systems. Also included are three survey papers on optimization, nonlinear filtering, and nonlinear systems. Recent advances are reported on the behavioral approach to systems, the relationship between differential games and robust control, estimation of diffusion processes, Markov processes, optimal control, hybrid control, stochastic control, spectral estimation, nonconvex quadratic programming, robust control, control algorithms and quantized linear systems. Innovative explorations are carried out on quantum systems from a control theory perspective, option valuation and hedging, three-dimensional medical visualization, computational structure biology image processing, and hierarchical approaches to complex systems, flow control, scheduling and force feedback in fluid mechanics. The contents reflect on past research accomplishments, current research activity, and future research directions in systems and control theory.

This book focuses on how the BOXES Methodology, which is based on the work of Donald Michie, is applied to ill-defined real-time control systems with minimal a priori knowledge of the system. The method is applied to a variety of systems including the familiar pole and cart. This second edition includes a new section that covers some further observations and thoughts, problems, and evolutionary extensions that the reader will find useful in their own implementation of the method. This second edition includes a new section on how to handle jittering about a system boundary which in turn causes replicated run times to become part of the learning mechanism. It also addresses the aging of data values using a forgetfulness factor that causes wrong values of merit to be calculated. Another question that is addressed is "Should a BOXES cell ever be considered fully trained and, if so, excluded from further dynamic updates". Finally, it expands on how system boundaries may be shifted using data from many runs using an evolutionary paradigm.

This book presents novel results by participants of the conference "Control theory of infinite-dimensional systems" that took place in January 2018 at the FernUniversitat in Hagen. Topics include well-posedness, controllability, optimal control problems as well as stability of linear and nonlinear systems, and are covered by world-leading experts in these areas. A distinguishing feature of the contributions in this volume is the particular combination of researchers from different fields in mathematics working in an interdisciplinary fashion on joint projects in mathematical system theory. More explicitly, the fields of partial differential equations, semigroup theory, mathematical physics, graph and network theory as well as numerical analysis are all well-represented.

This advanced textbook introduces the main concepts and advances in systems and control theory, and highlights the importance of geometric ideas in the context of possible extensions to the more recent developments in nonlinear systems theory. Although inspired by engineering applications, the content is presented within a strong theoretical framework and with a solid mathematical background, and the reference models are always finite dimensional, time-invariant multivariable linear systems. The book focuses on the time domain approach, but also considers the frequency domain approach, discussing the relationship between the two approaches, especially for single-input-single-output systems. It includes topics not usually addressed in similar books, such as a comparison between the frequency domain and the time domain approaches, bounded input bounded output stability (including a characterization in terms of canonical decomposition), and static output feedback stabilization for which a simple and original criterion in terms of generalized inverse matrices is proposed. The book is an ideal learning resource for graduate students of control theory and automatic control courses in engineering and mathematics, as well as a reference or self-study guide for engineers and applied mathematicians.

This monograph is devoted to the analysis and solution of singular differential games and singular $H_{\inf}$ control problems in both finite- and infinite-horizon settings. Expanding on the authors' previous work in this area, this novel text is the first to study the aforementioned singular problems using the regularization approach. After a brief introduction, solvability conditions are presented for the regular differential games and $H_{\inf}$ control problems. In the following chapter, the authors solve the singular finite-horizon linear-quadratic differential game using the regularization method. Next, they apply this method to the solution of an infinite-horizon type. The last two chapters are dedicated to the solution of singular finite-horizon and infinite-horizon linear-quadratic $H_{\inf}$ control problems. The authors use theoretical and real-world examples to illustrate the results and their applicability throughout the text, and have carefully organized the content to be as self-contained as possible, making it possible to study each chapter independently or in succession. Each chapter includes its own introduction, list of notations, a brief literature review on the topic, and a corresponding bibliography. For easier readability, detailed proofs are presented in separate subsections. Singular Linear-Quadratic Zero-Sum Differential Games and $H_{\inf}$ Control Problems will be of interest to researchers and engineers working in the areas of applied mathematics, dynamic games, control engineering, mechanical and aerospace engineering, electrical engineering, and biology. This book can also serve as a useful reference for graduate students in these area

The presence of uncertainty in a system description has always been a critical issue in control. The main objective of "Randomized Algorithms for Analysis and Control of Uncertain Systems, with Applications "(Second Edition) is to introduce the reader to the fundamentals of probabilistic methods in the analysis and design of systems subject to deterministic and stochastic uncertainty. The approach propounded by this text guarantees a reduction in the computational complexity of classical control algorithms and in the conservativeness of standard robust control techniques. The second edition has been thoroughly updated to reflect recent research and new applications with chapters on statistical learning theory, sequential methods for control and the scenario approach being completely rewritten.

Features:

. self-contained treatment explaining Monte Carlo and Las Vegas randomized algorithms from their genesis in the principles of probability theory to their use for system analysis;

. development of a novel paradigm for (convex and nonconvex) controller synthesis in the presence of uncertainty and in the context of randomized algorithms;

. comprehensive treatment of multivariate sample generation techniques, including consideration of the difficulties involved in obtaining identically and independently distributed samples;

. applications of randomized algorithms in various endeavours, such as PageRank computation for the Google Web search engine, unmanned aerial vehicle design (both new in the second edition), congestion control of high-speed communications networks and stability of quantized sampled-data systems.

""

"Randomized Algorithms for Analysis and Control of Uncertain Systems" (second edition) is certain to interest academic researchers and graduate control students working in probabilistic, robust or optimal control methods and control engineers dealing with system uncertainties.

The present book is a very timely contribution to the literature. I have no hesitation in asserting that it will remain a widely cited reference work for many years.

M. Vidyasagar

"

This book is a useful tool for researchers in both academia and industry who are interested in improving the performances of magnetic recording systems using new coding schemes. Coding and Iterative Detection for Magnetic Recording Channels proposes several new approaches for enhancing the performance of magnetic recording systems by coding and interpolated timing recovery. It provides a tutorial introduction to turbo codes, LDPC codes and their iterative detection schemes. The main emphasis, however, is placed on the simplification of the detector structures for the implementation of various codes. Chapter 1 introduces the model for magnetic recording channels and the challenges to the read channel detector designs. Chapter 2 discusses the turbo codes and the turbo equalization structure for ISI channels. Chapter 3 summarizes the major concepts of LDPC codes and their iterative detection algorithms based on belief propagation. Chapter 4 introduces the Decision Aid Equalization (DAE) structure to simplify iterative detection for ISI channels. Chapter 6 proposes an interpolated timing recovery scheme that facilitates symbol timing recovery by its re-sampling' capability. The combination of the above-mentioned chapters leads to a new structure for implementing iterative detection on recording channels. Chapter 5 deviates from iterative detection to propose a simple code, the Interleaved Parity Check (IPC) code, and its reduced-complexity decoder, which is considered practical for implementation with currently available integrated circuit technology. Chapter 7 summarizes the book with a discussion on future research topics in this field. Coding and Iterative Detection for MagneticRecording Channels is a valuable reference for researchers and design engineers working on signal processing and coding for magnetic recording channels. It may also be used as a graduate text for courses on turbo codes.

This text provides one of the first book-length studies on the innovative and sustainable development of complex systems in the era of digital transformations, combining quantitative data from several countries with detailed qualitative accounts at the national level. In particular, the book covers the basic concepts, methods, and cutting-edge research on innovation and sustainability in complex systems. Given its scope, the book will be of great interest and value to researchers and practitioners working across the social sciences and in a diverse range of areas in complexity science. Pursuing a multidisciplinary approach, the book is also an ideal resource for advanced undergraduate and graduate level courses in complexity science, sustainability research, economics, and development studies.

Cybernetic pioneer Warren McCullough asked: "What is a man, that he may know a number; and what is a number, that a man may know it?" Thinking along much the same lines, my question here is: "What is a creative mind, that it might emerge from a complex system; and what is a complex system, that it might give rise to a creative mind?" Complexity science is a fashionable topic these days. My perspective on complexity, however, is a somewhat unusual one: I am interested in complex systems science principally as it reflects on abstract mathematical, computational models of mind. In my three previous books, The Structure of Intelligence, Evolving Mind, and Chaotic Logic, I have outlined a comprehensive complex-systems-theoretic theory of mind that I now call the psynet model. This book is a continuation of the research program presented in my previous books (and those books will be frequently referred to here, by the nicknames EM and CL). One might summarize the trajectory of thought spanning these four books as follows. SI formulated a philosophy and mathem- ics of mind, based on theoretical computer science and the concept of "pattern. " EM analyzed the theory of evolution by natural selection in similar terms, and used this computational theory of evolution to establish the evolutionary nature of thought.