Primarily intended for physicians and health care professionals who are treating obese patients, this book explores current and future options for drug treatment of obesity puts them into perspective against available alternative treatments. Distinguished scientists and clinical investigators provide reviews of each individual topic, covering a wide range of subjects from pathophysiology of obesity to the benefits of weight loss. The core sections on pharmacotherapy deal with currently available drugs and drugs in pre-clinical development, complemented with sections on non-drug treatment and general therapeutic aspects to provide an integrated view of therapeutic approaches to the treatment of obesity and its associated syndromes.

This handbook of nutrition and diet provides information on food nutrients and their functions; food safety and distribution; food composition, consumption and utilization; adequacy of diet; and the nutritional management of diseases and disorders. It also discusses the effects of nutrition and diet on diseases of the bones, teeth, hair, kidneys, liver and nervous system.

Many health professionals today seem to approach sports nutrition and physical activity recommendations with a "one size fits all" approach. Surprisingly, little consideration goes into addressing the changing needs of athletes as they progress in age. Nutrition and Exercise Concerns of Middle Age addresses the specific nutritional and physical activity needs of active individuals thirty to sixty years old. Judy A. Driskell, one of the world's leading experts in the field of sports nutrition, brings together cutting-edge research on the nutritional needs and exercise recommendations for this quickly growing age group. Internationally acclaimed experts on nutrition and kinesiology unveil their research in sports nutrition, endurance and strength training, age-related disorders, and nutrition and exercise recommendations of health organizations. They also explore the role of diet and physical activity in reducing the risk of and in treating age-related diseases such as cancer and cardiovascular disease. Nutrition and Exercise Concerns of Middle Age is a valuable resource for nutritionists, physicians, dieticians, and researchers looking to access authoritative information on exercise and sports nutrition recommendations for middle-age adults.

Childhood Obesity Prevention and Treatment, Second Edition summarizes the latest scientific knowledge on obesity in children. This edition focuses on the developmental aspects of obesity, especially on the influences and factors predisposing individuals to obesity from early periods of life. This new body of knowledge stems from both basic research and recent epidemiological and clinical studies. All chapters are updated and special attention is given to the prevention of obesity in the context of developmental physiology, lifestyle modification, and dietary and physical activity approaches. Highlighting the most recent research, this timely book covers a broad range of aspects related to the prevention and management of childhood obesity. It emphasizes early intervention and an integrated behavioral approach to overcome the ongoing challenge of this global epidemic. Features * Updates all chapters and includes new research on growing populations of obesity in the Third World * Provides information on promoting health as a means to reduce obesity * Focuses on the developmental aspects of obesity

Health professionals are recognizing the major role that nutraceuticals play in health enhancement. As a result, there is a dramatic increase in research aimed at identifying new functional foods and nutraceuticals. There is not, however, a single source that presents this research in a thorough and accessible manner. Comprehensive and complete, the Dictionary of Nutraceuticals and Functional Foods is the first reference of its kind written explicitly for this rapidly developing field. The book provides clearly written, concise, science-based information on over 470 nutraceutical and functional food products and compounds. Each entry lists the most current information on the product or compound and its role in the promotion of health or the prevention of disease, as well as peer-reviewed literature references. In addition, this thorough reference contains 172 chemical structures, 102 figures, 73 schemes, and 64 tables to facilitate recognition and understanding. Concise and accessible, the Dictionary of Nutraceuticals and Functional Foods is a convenientsingle source reference that defines the most commonly used terms in the field of nutraceuticals and functional foods.

The Japanese Ministry of Health, Labor and Welfare, officially recognizing that various risk factors for disease are present in our environment, has proposed the concept of lifestyle-related diseases. These include those diseases that are tied to such lifestyle choices as excessive alcohol consumption, cigarette smoking, exposure to stress, and poor diet. Ongoing attention to this issue led to an International Symposium on Free Radicals and Health: Molecular Interventions and Protection of Lifestyle-Related Diseases bringing together the top experts in that area. With the belief that the recognition of the occurrence of risk factors and their identification are important to overcoming lifestyle-related diseases, three of those experts invited prominent participants at the symposium to contribute to a book. Molecular Interventions in Lifestyle-Related Diseases is the result of that effort. This book is divided into three main sections: Free Radicals, Lifestyle-Related Diseases, and Their Protection Free Radicals, Brain Diseases, and Their Protection Nutraceuticals, Functional Foods, Micronutrients, and Pharmacological Interventions When bad lifestyle choices cause oxidants and free radicals to have a negative influence on cell signaling and gene expression, lifestyle-related diseases are set into motion, which in turn lead to further oxidative stress. Molecular Interventions in Lifestyle-Related Diseases addresses the molecular basis of free radicals and lifestyle-related diseases and preventive/therapeutic approaches including the use of nutraceuticals, functional foods, and pharmacological interventions. Each section contains several chapters addressing critical molecular mechanisms, therapeutic interventions, and other issues of relevance to human health that will be of interest to students and researchers in the health professions including nutritional and environmental scientists, molecular and cell biologi

This third edition reviews the epidemiology, policies, programs and outcome indicators that are used to determine improvements in nutrition and health that lead to development. This greatly expanded third edition provides policy makers, nutritionists, students, scientists, and professionals with the most recent and up-to-date knowledge regarding major health and nutritional problems in developing countries. Policies and programs that address the social and economic determinants of nutrition and health are now gaining in importance as methods to improve the status of the most vulnerable people in the world. This volume provides the most current research and strategies so that policy makers, program managers, researchers and students have knowledge and resources that they can use to advance methods for improving the public's health and the development of nations. The third edition of Nutrition and Health in Developing Countries takes on a new context where the word "developing" is now a verb and not an adjective.

This collection takes an interdisciplinary look at how the transformation towards plant-based diets is becoming more culturally acceptable, economically accessible, technically available and politically viable. We offer strategies for achieving sustainable food systems without having to forgo succulence, sensuality and sacredness of food. Shifting food systems is one of humanity's biggest challenges and greatest opportunities. This book explores adaptable and health-promoting plant-based diets, which by their nature can support nourishing environmental, social, ethical, political, and economic outcomes. In this book, detailed descriptions are provided of what constitutes a healthy plant-based diet and active lifestyle. Readers are invited to engage with a community of practitioners delving more deeply into strategies for transitioning societies to greater succulence and sustainability. Throughout the first section of the book, environmental challenges and opportunities for reversing climate change are highlighted as our most urgent action. The focus then turns to global food systems and the intersections that are undermining human and animal health. The final section offers preventative approaches and encourages reorienting systems of law, economics and education to exemplify integrity, coordination, coherence and compassion. This book will be of interest to students and academics, as well as policy professionals in all fields engaging with complex issues and systems analyses. It will be of value to those working in health services, policy development, agriculture, economic development, and social change as it provides steps to enhance well-being, pathways to increase jobs in the green economy, and practical ideas to reverse greenhouse gas emissions. It may also be a superb guide for individuals and families looking to become vibrant eaters and leaders.

Is any food safe? Will mad cow disease kill us all? How many calories are really in your restaurant Caesar salad? Modern consumers are besieged with conflicting messages about food and nutrition, making it difficult for the lay person to know what to believe. This no-nonsense resource explores the latest controversies in the field of food and nutrition, presenting readers with the varying opinions and underlying facts that fuel these debates. Fifteen chapters focus on hot topics like organic food, bottled water, and deadly bacterial outbreaks as well as lesser known issues such as food irradiation, vitamin supplementation, animal growth hormones, and more.

One of the few resources of its kind, this informative reference is perfect for high school and college students and the conscientious consumer. Since most books on food and diet approach the issues with a clear agenda, this work's unbiased tone and evenhanded treatment of information make it a particularly valuable tool. Features include a detailed index, 20 black and white illustrations, and a rich and deep bibliography of print and electronic materials useful for further research.

Focusing on the importance of functional foods and their secondary metabolites for human health, this volume presents new insights with scientific evidence on the use of functional foods in the treatment of certain diseases. The plants covered and their bioactive compounds are easily accessible and are believed to be effective with fewer side effects in comparison with modern drugs in the treatment of different diseases. The plants contain chemical compounds that can modify and modulate biological systems, eliciting therapeutic effects. Some plants and derived products mentioned include black carrot, olive oil, citrus peel, grapes, candy leaf, cereals and grains, and green and black tea. The volume is divided into four sections that cover these topics: Functional foods for human health: the available sources, biochemistry, structural composition, and different biological activities, especially antioxidant activity. Pharmacological aspects of fruits and vegetables: the extraction of bioactive molecules, phytochemistry, and biological activities of a selection of plants. Pharmacological aspects of natural products: bioactive compounds, structural attributes, bioactivity of anthocyanin, piceatannol, and a review of the ethnobotany and medicinal properties of green and black tea. Pharmacological aspects of cereals and grains: the health benefits of flaxseed, wheatgrass juice, and use and therapeutic potential as supplements for disease management.

"Nutrition in Infancy: Volume 2" is a very useful resource for all clinicians treating and preventing nutritional problems in infants. This volume covers a wide range of topics that support wellness in infants through the prevention and treatment of infectious diseases, malnutrition, and developmental and genetic abnormalities. A variety of chapters deal with nutrients for infants with disabilities, surgery, and other special needs.

The sections in this volume discuss GI Tract Considerations, Formulas, probiotics, hormones and lipids in the health and disease of infants, and the growth and development of infants. In "Nutrition in Infancy: Volume 2," a wide range of nutritional and food related therapies to prevent or ameliorate disease, growth retardation and promote health are outlined. The latest developments in diagnostic procedures and nutritional support are also included. Written by a group of international experts, this volume is an indispensable new reference for clinicians with an interest in the nutrition and health of pregnant mothers and their infants.
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During the past twenty years there has been a dramatic increase in obesity in the United States. An estimated thirty percent of adults in the US are obese; in 1980, only fifteen percent were. The issue is gaining greater attention with the CDC and with the public health world in general. This book will offer practical information about the methodology of epidemiologic studies of obesity, suitable for graduate students and researchers in epidemiology, and public health practitioners with an interest in the issue.
The book will be structured in four main sections, with the majority of chapters authored by Dr. Hu, and some authored by specialists in specific areas. The first section will consider issues surrounding the definition of obesity, measurement techniques, and the designs of epidemiologic studies. The second section will address the consequences of obesity, looking at epidemiologic studies that focus on cardio-vascular disease, diabetes, and cancer The third section will look at determinants obesity, reviewing a wide range of risk factors for obesity including diet, physical activity and sedentary behaviors, sleep disorders, psychosocial factors, physical environment, biochemical and genetic predictors, and intrauterine exposures. In the final section, the author will discuss the analytical issues and challenges for epidemiologic studies of obesity.

Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.

Why has breastfeeding re-asserted itself over the last twenty years, and why are the government, the scientific and medical communities, and so many mothers so invested in the idea? In Is Breast Best? Joan B. Wolf challenges the widespread belief that breastfeeding is medically superior to bottle-feeding. Despite the fact that breastfeeding has become the ultimate expression of maternal dedication, Wolf writes, the conviction that breastfeeding provides babies unique health benefits and that formula feeding is a risky substitute is unsubstantiated by the evidence. In accessible prose, Wolf argues that a public obsession with health and what she calls "total motherhood" has made breastfeeding a cause celebre, and that public discussions of breastfeeding say more about infatuation with personal responsibility and perfect mothering in America than they do about the concrete benefits of the breast. Parsing the rhetoric of expert advice, including the recent National Breastfeeding Awareness Campaign, and rigorously questioning the scientific evidence, Is Breast Best? uncovers a path by which a mother can feel informed and confident about how best to feed her thriving infant-whether flourishing by breast or by bottle.

This volume provides in a conveniently accessible package a comprehensive collection of accurate and timely information on the management of patients with diarrhea, both in pediatric age and in the adult. As medical knowledge has recently expanded in this area, this volume is full of new practical, clinically useful material for the busy clinician. Illustrations are emphasized to permit rapid acquisition of practical information that is not readily available in the major texts. Each chapter is concise, concentrating on "clinical pearls," and new advances in diagnostic and therapeutic technology. Each chapter discusses the relative costs of diagnostic and therapeutic options to permit financial considerations to be taken into account in the decision making process. Additional unique features include, summaries of key points, recommendations, and indications for requesting GI subspecialty consultation. Providing a comprehensive but practical overview of the issues surrounding the diarrheal diseases, this volume will prove of great value and utility to gastroenterologists, surgeons, internists, primary care physicians.

Integrative Weight Management: A Guide for Clinicians intends to educate physicians and nutritionists about the wide ranges of approaches to weight control from non-traditional sources. The options for weight management in conventional practices are limited to a small number of medications, a confusing array of dietary approaches and surgical procedures with their inherent risks and complications. Unfortunately medical practitioners are not exposed to nutrition and weight control principles during training and thus are reluctant to manage their patients weight control issues. This volume is structured into 4 sections: Introduction to Weight Management Disorders; Morbidity and Mortality of Obesity; Therapy of Obesity; and Integrative Medicine and Obesity. Integrative Weight Management: A Guide for Clinicians represents a powerful collaboration of dozens of leading experts in the fields of nutrition, weight management and integrative medicine who have managed countless numbers of patients and summarized the research from thousands of articles to create an up-to- date state of the art guide for healthcare practitioners, allied health professionals and public health authorities who manage those who are overweight/obese along with the associated metabolic consequences.

Concepts in Fitness Programming presents comprehensive material about various aspects of exercise testing and prescription in a simple, straightforward manner. Intended for individuals who design exercise and fitness programs but who lack extensive background in fitness training, this book provides a wealth of knowledge beyond the basic "how to's" of fitness programming. Exercisers require some background in fitness and exercise-related injuries and nutrition. For safety, exerciser and instructor need to know the medical problems that limit exercise capacity or eliminate someone from safely exercising, and how drugs used for medical problems influence exercise. Background in medical terminology and the interrelationships of disease and exercise are useful for understanding exercise literature.

Increased oxidative stress due to the production of excessive amounts of free radicals along with the effects of chronic inflammation plays a major role in the initiation and progression of most chronic diseases. In addition, increased release of glutamate plays a central role in the pathogenesis of various disorders. This second edition of Micronutrients in Health and Disease proposes a novel concept that in order to simultaneously and optimally reduce oxidative stress, chronic inflammation, and glutamate, it is essential to increase levels of antioxidant enzymes as well as levels of dietary and endogenous antioxidant compounds at the same time. This is accomplished by activating the Nrf2 pathways and by increasing the levels of antioxidant compounds and B-vitamins through supplementation. This book proposes a mixture of micronutrients that achieves this above goal. The mixture of micronutrients together with modification in diet and lifestyle may reduce the risk of chronic diseases and in combination with standard care, may improve the management of these diseases. KEY FEATURES * Provides evidence in support of the idea that increased oxidative stress, chronic inflammation, and glutamate are involved in the pathogenesis of chronic diseases. * Contains three new chapters on Huntington's disease, Autism spectra, and Prion disease. * Discusses the role of microRNAs in the pathogenesis of chronic diseases. * Presents information on regulation of the expression of microRNAs by reactive oxygen species and antioxidants. Micronutrients in Health and Disease, Second Edition serves as a valuable resource for those seeking to promote healthy aging and prevent and improved management of chronic diseases.

Whole grains play an important role in healthy diets, due to their potential role in minimizing the risk factors for several diseases. Thus the need for a comprehensive work that addresses all aspects of whole grain technology including processing, product development and nutrition values. This book covers the technological, nutritional and product development aspects of all whole grains including wheat, rice, barley, rye, sorghum, millet, maize, and oats among others. The book will review and summarize current knowledge in whole grains with the intent of being helpful to the food industry in the development of high-quality whole grain products. Key Features: Covers the technology for whole grain processing Promotes the utilization of whole grain products Provides the information about the nutritional components of whole grains Explores the health benefits of whole grains Presents the latest trends and safety concerns of whole grains The chapters include amaranth, barley, brown rice, buckwheat, maize, millets, oats, quinoa, rye, sorghum, and wheat. In addition, current trends in processing technology and product development for whole grains are explained in detail in a separate chapter. The last chapter deals with the food safety management of whole grains. Contributions from global experts in this field make this book a key reference material for all aspects of whole grains. This book is suitable for students, scientists, and professionals in food science, food engineering, food technology, food processing, product development, food marketing, nutrition and other health sciences.

Hidden Hunger is an increasing problem even in developed countries, whose potential negative consequences on long-term health are often overlooked and underestimated. Chronic malnutrition is at the core of the global hunger challenge facing science, politics, and economics. In plain language and with moving examples, Hans K. Biesalski describes how hidden hunger affects human health long before malnutrition becomes obvious. Worldwide, over one third of deaths among children under 5 years of age is associated with malnutrition. As poverty is the main reason for hidden hunger, addressing this dire challenge requires long-term policies. Land grabbing and climate change seriously counteract a lot of efforts to overcome hidden hunger. This book is a highly impressive call to action. Investment in agriculture and in particular in small-scale farmers to improve subsistence farming are among the approaches suggested to reach a sustainable solution. The author is head of the department of biochemistry and nutrition and managing director of the Food Security Center at the University of Hohenheim, Germany. He is a member of numerous advisory and expert groups for the World Health Organization (WHO), the Food and Agriculture Organization (FAO) and the Global Forum on Food Security and Nutrition.

Reprising The 2017 American Library Association Outstanding Academic Title award-winning A-Z Guide to Food As Medicine, this new edition explores the physiological effects of more than 250 foods, food groups, nutrients, and phytochemicals in entries that include: Definition and background information such as traditional medicinal use, culinary facts, and dietary intake and deficiency information Scientific findings on the physiological effects of foods, food groups, and food constituents Bioactive dose when known, such as nutrient Dietary Reference Intakes focusing on 19-to-50-year-old individuals Safety highlights, such as nutrient Tolerable Upper Intake Levels A health professional's comprehensive nutrition handbook that includes all nutrients, nutrient functions, "good" and "excellent" sources of nutrients, nutrient assessment, and deficiency symptoms, as well as summaries of foods, food groups, and phytochemicals. New to the Second Edition: Disease- and condition-focused Index that leads readers to foods used to manage specific conditions and diseases Focus on practical recommendations for health maintenance and disease prevention, including tables, insets, and updated scientific findings on more than a dozen new foods Accompanying teaching aids and lesson plans available online at http://www.crcpress.com Features: Dictionary-style summaries of the physiological effects of foods, food groups, nutrients, and phytochemicals alphabetically listed for quick access Approximately 60 B & W images of foods; informational tables and insets that define or illustrate concepts such as drug terminologies, classes of phytochemicals, and medicinal aspects of foods and of a plant-based diet Over 1,000 scientific references from peer-reviewed sources, including The Academy of Nutrition and Dietetics Evidence Analysis Library, and position statements of major health organizations

Magnesium is an essential mineral required by humans, playing an important role in multiple biochemical processes as well as preventing and managing several diseases and disorders. Deficiencies of magnesium can lead to a wide range of medical conditions, including cardiovascular disease, diabetes, and hypertension. With myocardial infarction and stroke being the first and fifth cause of mortality in the United States, the pharmaceutical industry has been trying to produce therapies that reduce co-morbidity and mortality. Recent observational studies of magnesium have added to the list of potential therapeutic modalities that have been proven useful in reducing hypertension, stroke sequalae, metabolic syndrome/dyslipidemia, and inflammatory diseases. Magnesium therapeutic modalities also have impacts in the fields of neurology, the elderly, and in obstetrics. Magnesium: Applications in Clinical Medicine explores the many uses of magnesium and its applications in clinical medicine. Features: Presents information on the impacts magnesium has on various aspects of health conditions and disease prevention. Describes magnesium usage in treating and managing several conditions including dyslipidemia, migraine, metabolic syndrome, and high blood pressure. Discusses magnesium therapy in stroke and magnesium deficiency in attention deficit hyperactivity disorder. Promotes knowledge of overall health and wellness that can be applied in any specialty of medicine. This book encompasses various uses of magnesium in a clinical setting ranging from its role in maintaining homeostasis, to its uses in the fields of dermatology, cardiology, neurology, and in obstetrics. Written by contributors who are experts in their fields, it is a comprehensive collaboration of this ubiquitous dietary supplement's applications in clinical medicine.

Nutrition manuals and textbooks are usually written to meet the needs of nutritionists or would-be nutritionists. This manual has been written to meet the needs of health professionals who are not nutritionists, including physicians, nurses and pharmacists. The acquaints readers in these professions with the principles of nutrition and the application of nutrition to the better delivery of health care.

It is the purpose of this book to try to offer a modern perspective on the importance of vitamins in human biology and medicine. There have been recent revivals of attempts to use vitamins as therapeutic agents by administering doses many times the recommended allowance. This use or 'megavitamin therapy' is reviewed by Dr. Reynold Spector, with particular emphasis on vitamin entry to the central nervous system. Of related interest is the chapter by Dr. John Blass discussing central nervous system manifestations of thiamin deficiency, and also the contribution by Ms. Fiona Cumming and clinical toxicity of vitamin supplementation.

Written by an experienced clinician and researcher in the field, this reference provides practical information on the clinical recording techniques, physiologic origins, and applications of electroretinogram (ERG), electro-oculogram (EOG), and visual evoked potential (VEP) tests.