Biological systems are very special substrates for engineering-uniquely the products of evolution, they are easily redesigned by similar approaches. A simple algorithm of iterative cycles of diversification and selection, evolution works at all scales, from single molecules to whole ecosystems. In the little more than a decade since the first reported applications of evolutionary design to enzyme engineering, directed evolution has matured to the point where it now represents the centerpiece of industrial biocatalyst development and is being practiced by thousands of academic and industrial scientists in com- nies and universities around the world. The appeal of directed evolution is easy to understand: it is conceptually straightforward, it can be practiced without any special instrumentation and, most important, it frequently yields useful solutions, many of which are totally unanticipated. Directed evolution has r- dered protein engineering readily accessible to a broad audience of scientists and engineers who wish to tailor a myriad of protein properties, including th- mal and solvent stability, enzyme selectivity, specific activity, protease s- ceptibility, allosteric control of protein function, ligand binding, transcriptional activation, and solubility. Furthermore, the range of applications has expanded to the engineering of more complex functions such as those performed by m- tiple proteins acting in concert (in biosynthetic pathways) or as part of mac- molecular complexes and biological networks.

Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in their historical contexts. The contributing authors outline the history and original context of discovery of symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infectious heredity. By applying key insights from the areas of molecular (phylo)genetics, microbiology, virology, ecology, systematics, immunology, epidemiology and computational science, they demonstrate how reticulate evolution impacts successful survival, fitness and speciation. Reticulate evolution brings forth a challenge to the standard Neo-Darwinian framework, which defines life as the outcome of bifurcation and ramification patterns brought forth by the vertical mechanism of natural selection. Reticulate evolution puts forward a pattern in the tree of life that is characterized by horizontal mergings and lineage crossings induced by symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow and infective heredity, making the "tree of life" look more like a "web of life." On an epistemological level, the various means by which hereditary material can be transferred horizontally challenges our classic notions of units and levels of evolution, fitness, modes of transmission, linearity, communities and biological individuality. The case studies presented examine topics including the origin of the eukaryotic cell and its organelles through symbiogenesis; the origin of algae through primary and secondary symbiosis and dinoflagellates through tertiary symbiosis; the superorganism and holobiont as units of evolution; how endosymbiosis induces speciation in multicellular life forms; transferrable and non-transferrable plasmids and how they symbiotically interact with their host; the means by which pro- and eukaryotic organisms transfer genes laterally (bacterial transformation, transduction and conjugation as well as transposons and other mobile genetic elements); hybridization and divergence with gene flow in sexually-reproducing individuals; current (human) microbiome and viriome studies that impact our knowledge concerning the evolution of organismal health and acquired immunity; and how symbiosis and symbiogenesis can be modelled in computational evolution.

Haldane, Mayr, and Beanbag Genetics presents a summary of the classic exchange between two great biologists - J.B.S. Haldane and Ernst Mayr - regarding the value of the contributions of the mathematical school represented by J.B.S. Haldane, R.A. Fisher and S. Wright to the theory of evolution. Their pioneering contributions from 1918 to the 1960s dominated and shaped the field of population genetics, unique in the annals of science. In 1959, Mayr questioned what he regarded as the beanbag genetic approach of these pioneers to evolutionary theory, "an input or output of genes, as the adding of certain beans to a beanbag and the withdrawing of others." In 1964, Mayr's contention was refuted by Haldane in a remarkably witty, vigorous and pungent essay, "A defense of beanbag genetics" which compared the mathematical theory to a scaffolding within which a reasonably secure theory expressible in words may be built up. Correspondence between Haldane and Mayr is included.
Beanbag genetics has come a long way since 1964. Mayr's (1959) critique of simple uncomplicated population genetics is no longer valid. Population genetics today includes much more than Mayr's beanbag genetics. Population genetics models now include multiple factors, linkage, dominance and epistasis. These may be regarded as the advanced beanbag models. Furthermore, population genetics and developmental genetics have become interdependent. Contemporary beanbag genetics includes molecular clocks, nucleotide diversity, coalescence and DNA-based phylogenetic trees, along with the four major holdovers from classical genetics, mutation, selection, migration and random drift. Molecular genetics has made it possible to study evolution rates at the nucleotide level. It is also possible today to compare DNA similarities and divergence in diverse species of animals and plants, which were not previously crossable.

Polls show that 45% of the American public believes that humans were created about 10,000 years ago and that evolution is a fictitious myth. Another 25% believes that changes in the natural world are directed by a supernatural being with a particular goal in mind. This thinking clashes head on with scientific findings from the past 150 years, and there is a dearth of public critical thinking about the natural world within a scientific framework.
Evolution and Religious Creation Myths seeks to educate and arm the public on the differences between myth and science, fiction and theory. The book begins with a whirlwind tour of creation stories from several religions. The authors then explore how certain forms of religious fundamentalism clash with the science of evolution. They review how creationists and intelligent design proponents misuse and misrepresent scientific terminology and conclusions to further their own agendas. How do scientists respond to this threat? Modern science, which includes a level of indeterminacy, or chance, cannot support the premise that a supernatural designer engineered nature for a particular purpose in a deterministic fashion. This holds true for the creation of the universe, the appearance of the first biological molecules, chemical evolution, and the evolution of life forms through mutation, natural selection, and genetic drift. Instead, human biological and cultural evolution is described within a genetic framework. Scientists use a barrage of genetic tests and DNA phylogenies to support the scientific basis for evolution. For anyone who has ever needed to argue why evolution and creationism are not both valid theories that deserve equal attention, this book clearly defines the difference between theory and myth. Scientists, teachers, and defenders of the truth should read this book in preparation for when they are called upon to respond.

This set of lecture notes gives a first coherent account on a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving field and covers the whole range from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.

This book is divided in two parts, the first of which shows how, beyond paleontology and systematics, macroevolutionary theories apply key insights from ecology and biogeography, developmental biology, biophysics, molecular phylogenetics and even the sociocultural sciences to explain evolution in deep time. In the second part, the phenomenon of macroevolution is examined with the help of real life-history case studies on the evolution of eukaryotic sex, the formation of anatomical form and body-plans, extinction and speciation events of marine invertebrates, hominin evolution and species conservation ethics. The book brings together leading experts, who explain pivotal concepts such as Punctuated Equilibria, Stasis, Developmental Constraints, Adaptive Radiations, Habitat Tracking, Turnovers, (Mass) Extinctions, Species Sorting, Major Transitions, Trends and Hierarchies - key premises that allow macroevolutionary epistemic frameworks to transcend microevolutionary theories that focus on genetic variation, selection, migration and fitness. Along the way, the contributing authors review ongoing debates and current scientific challenges; detail new and fascinating scientific tools and techniques that allow us to cross the classic borders between disciplines; demonstrate how their theories make it possible to extend the Modern Synthesis; present guidelines on how the macroevolutionary field could be further developed; and provide a rich view of just how it was that life evolved across time and space. In short, this book is a must-read for active scholars and because the technical aspects are fully explained, it is also accessible for non-specialists. Understanding evolution requires a solid grasp of above-population phenomena. Species are real biological individuals and abiotic factors impact the future course of evolution. Beyond observation, when the explanation of macroevolution is the goal, we need both evidence and theory that enable us to explain and interpret how life evolves at the grand scale.

This book is about what science frequently dodges or even denies: subjective life as experienced by animals as well as humans. Mixing what is known from science with some novel ideas, science writer William Libaw provides a provocative and stimulating thesis on the origins and evolution of consciousness.
Among the intriguing ideas presented are the following: For the earliest animals that had it, subjective experience itself had Darwinian adaptiveness in a rapidly changing environment; the use of gestures and deception among apes and some birds suggests conscious concepts in their mental activity; complete spoken language came first from the mouths of a group of children who inherited the previously unused genetic language capability; and human males have retained the animal rutting instinct and amplified it with conceptual prurience, which leads them to eroticize females, and sometimes pressure them to have sex.
As the subjective world of any other creature cannot be observed directly by any of us, this book plays detective to deduce from gestures, deceptive behavior, and language some of the concepts that play a key role in ape and human minds.How We Got to Be Human is an interesting and original synthesis of a great deal of evidence and ideas about the origins and nature of our subjective minds.

Sex Differences serves as an advanced text for courses in evolutionary and human biology, psychology, and sexuality and gender studies. It also serves as a reference source for academic professionals in these disciplines. The book covers the evolution of sex and sex differences, and sex differences and sexual strategies in non-human and human animals. The final chapter addresses issues of sex and gender in interpersonal relationships, organizations and politics. Diagrams, graphs, charts, and tables illustrate key concepts; cartoons and photos provide visual breaks and an element of humor.
Key Features
* Examines sexual differences from a multi-level comparative approach
* Contains a thorough coverage of literature through 1998 and into 1999
* Illustrates pages with a generous use of cartoons, photos, figures, and diagrams
* Invites bonus learning with special interest boxes interspersed throughout text
* Presents a critical analysis
* Includes a combination of feminist and evolutionary thinking

This book focuses on how climatic change during the last fifteen million years - especially the last three million - has affected human evolution and other evolutionary events. Leading evolutionists and physical geologists from all over the worldauthorities on such subjects as paleoceanography, palynology, mammalian paleontology, and paleoanthropology - address the relationship between climatic and biotic evolution, presenting and integrating the most up-to-date research in their fields. Among the subjects discussed are: global and regional climatic changes; tectonism and its effects on climate; the evolution of biomes and mammals; the ways climate might have influenced the origins of hominid species; and the evolution of hominid morphologies and behaviors. The book draws on the comparatively rich data base of the Late Neogene and includes many new data sets and hypotheses on paleoclimatic changes and on floral and mammalian evolution.

Seymour W. Itzkoff is one of the world's leading intelligence researchers. His exciting new book Our Unfinished Biological Revolution offers a bold and highly original new study on the evolution of human intelligence from the origin of life to our times. With the help of evolutionary theory, Itzkoff explains the nature of human intelligence as we know it today. Most importantly, it demonstrates that evolution led to the rise of what intelligence researchers call the general intelligence factor: the human ability to plan ahead and solve problems for which natural selection did not prepare us. The book also argues that humans vary in intelligence (as with all traits shaped by Darwinian evolution), and hence in their propensity to think abstractly and anticipate long-term consequences of their actions. Our Unfinished Biological Revolution explores the social implications of these two factors as they unfold in modern technological societies, in which intelligence plays an increasingly important role. Finally, the book argues that human intelligence may offer our best hope in solving the daunting problems of the present era?including population growth, the exhaustion of natural resources, and the rise of simplistic and devastating ideologies.

'Brilliant, eye-opening, and absolutely inspiring - and a riveting read.' Cass Sunstein, author of How Change Happens and co-author of Nudge What is the secret to humanity's evolutionary success? Could it be our strength, our intellect... or something much nicer? From the authors of New York Times bestseller The Genius of Dogs comes a powerful new idea about how 'friendliness' is the key factor in the flourishing of our species. Hare and Woods present an elegant new theory called self-domestication, looking at examples of co-operation and empathy and what this can tell us about the evolutionary success of Homo sapiens...

Rough-and-tumble play provided one of the paradigmatic examples of the appli- tion of ethological methods, back in the 1970's. Since then, a modest number of - searchers have developed our knowledge of this kind of activity, using a variety of methods, and addressing some quite fundamental questions about age changes, sex diff- ences, nature and function of behaviour. In this chapter I will review work on this topic, mentioning particularly the interest in comparing results from different informants and different methods of investigation. Briefly, rough-and-tumble play (or R&T for short) refers to a cluster of behaviours whose core is rough but playful wrestling and tumbling on the ground; and whose general characteristic is that the behaviours seem to be agonistic but in a non-serious, playful c- text. The varieties of R&T, and the detailed differences between rough-and-tumble play and real fighting, will be discussed later. 2. A BRIEF HISTORY OF RESEARCH ON R&T In his pioneering work on human play, Groos (1901) described many kinds of rough-and-tumble play. However, R&T was virtually an ignored topic from then until the late 1960's. There was, of course, a flowering of observational research on children in the 1920s and 1930s, especially in North America; but this research had a strong practical o- entation, and lacked the cross-species perspective and evolutionary orientation present in Groos' work.

Most organisms and populations have to cope with hostile environments, threatening their existence. Their ability to respond phenotypically and genetically to these challenges and to evolve adaptive mechanisms is, therefore, crucial. The contributions to this book aim at understanding, from a evolutionary perspective, the impact of stress on biological systems. Scientists, applying different approaches spanning from the molecular and the protein level to individuals, populations and ecosystems, explore how organisms adapt to extreme environments, how stress changes genetic structure and affects life histories, how organisms cope with thermal stress through acclimation, and how environmental and genetic stress induce fluctuating asymmetry, shape selection pressure and cause extinction of populations. Finally, it discusses the role of stress in evolutionary change, from stress induced mutations and selection to speciation and evolution at the geological time scale. The book contains reviews and novel scientific results on the subject. It will be of interest to both researchers and graduate students and may serve as a text for graduate courses.

The volumes in this set, originally published between 1913 and 1997, draw together research by leading academics in the area of evolution and provide a rigorous examination of related key issues. The collection examines evolution from a broad range of disciplines, from the anthropological development of modern society, to the scientific examinations of cellular and genetic evolution. The collection includes volumes across the disciplines of biology, natural history, anthropology, sociology and religion. The 15 books that comprise this collection include rigorous examinations into the psychological evolution of the brain, philosophical and theological examinations of evolution, analysis of genetic and cellular evolution, discussions of Darwinian theory, the affect of survival of the fittest from both genetic and political standpoints and examinations into the affinity between man and ape. This collection brings back into print a collection of insightful and detailed books on the diverse subject of evolution and will be a must have resource for academics and students, not only of biology and anthropology, but of history, psychology and religion.

The diversity of social behavior among birds and primates is surpassed only by members of the Hymenopteran insects, including bees, ants, and the genus Polistes, or paper-wasps. This volume combines incisive reviews and new, unpublished data in studies of paper-wasps, a large and varied group whose life patterns are often studied by biologists interested in social evolution. While this research is significant to the natural history of paper-wasps, it also applies to topics of general interest such as the evolution of cooperation, social parasitism, kin recognition, and the division of labor.

Given the rapidly developing area of evolutionary medicine and public health, The Arc of Life examines ways in which research conducted by biological anthropologists can enrich our understanding of variation in human health outcomes. The book aims not only to showcase the perspective that biological anthropologists bring to the burgeoning field of evolutionary medicine, but to underscore the context of human life history -- especially the concept of evolutionary trade-offs and the ensuing biological processes that can affect health status over the life course. This dual emphasis on life history theory and life cycle biology will make for a valuable and unique, yet complementary, addition to books already available on the subject of evolution and health. The book consolidates diverse lines of research within the field of biological anthropology, stimulates new directions for future research, and facilitates communication between subdisciplines of human biology operating at the forefront of evolutionary medicine.

Volume: 1 Publisher: London, J. Murray Publication date: 1871 Subjects: Evolution Natural selection Heredity Human beings -- Origin Evolution Notes: This is an OCR reprint. There may be numerous typos or missing text. There are no illustrations or indexes. When you buy the General Books edition of this book you get free trial access to Million-Books.com where you can select from more than a million books for free. You can also preview the book there.

Why do minds exist? How did mud and stone develop into beings that can experience longing, regret, love and compassion-beings that are aware of their own experience? Until recently, science offered few answers to these existential questions. Journey of the Mind is the first book to offer a unified account of the mind that explains how consciousness, language, the Self and civilisation emerged incrementally out of chaos. The journey begins three billion years ago with the emergence of the simplest possible mind, a nanoscopic archeon, then ascends through amoebas, worms, frogs, birds, monkeys and AI, examining successively smarter ways of thinking. The authors explain the mathematical principles generating conscious experience and show how these principles led cities and democratic nations to develop new forms of consciousness-the self-aware "superminds". Journey of the Mind concludes by contemplating a higher stage of consciousness already emerging-and the ultimate fate of all minds in the universe.

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms.

We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume."Ecological Genomics"covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life.

"Ecological Genomics"covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.

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The poles undergo climate changes exceeding those in the rest of the world in terms of their speed and extent, and have a key role in modulating the climate of the Earth. Ecosystems adapted to polar environments are likely to become vulnerable to climate changes. Their responses allow us to analyse and foresee the impact of changes at lower latitudes. We need to increase our knowledge of the polar marine fauna of continental shelves, slopes and deep sea, as identifying the responses of species and communities is crucial to establishing efficient strategies against threats to biodiversity, using international and cross-disciplinary approaches. The IPY 2007-2009 was a scientific milestone. The outstanding contribution of Marine Biology is reflected in this volume and the next one on "Adaptation and Evolution in Marine Environments - The Impacts of Global Change on Biodiversity" from the series "From Pole to Pole", making these volumes a unique and invaluable component of the scientific outcome of the IPY.

In The Descent of Man, Charles Darwin (1809-1882) focuses special attention on the origin and history of our own species, a subject he had avoided in previous writings on evolution. He claims that the human animal is closest in ancestry to the two African pongids or anthropoid apes (chimpanzees and gorillas). Further, Darwin held that our species and these two pongids differ merely in degree rather than in kind -- a controversial view that contradicted religious doctrine. The Descent of Man (1871) looks at the emergence of humans in terms of primate evolution. Darwin presents a strictly mechanistic and materialistic interpretation of our species that is free from superstition and spiritualism.

Spontaneous self-cloning or clonality is a widespread phenomenon in the plant kingdom, and has a wide array of ecological and evolutionary implications. This volume is the outcome of an international workshop on clonal plant biology aimed at illustrating current progress and recent developments in the scientific study of clonality in plants. The first section of this book includes a collection of original research articles which demonstrate the wide variety of approaches and scientific challenges linked to clonality in plants. The topics covered in this section include ecological and evolutionary implications of sexual versus asexual propagation, including life-history evolution and sex-ratio dynamics, the importance of internal resource transport and remobilization of storage products for the invasiveness and competitiveness of clonal plants, a survey of clonal growth forms in grassland communities, and studies on the interactions between clonal plants and animals and fungi. The approaches used range from experimental studies on a broad variety of systems to mathematical modeling of clonal growth and its consequences. The second part features discussion and review papers on a diverse array of subjects, ranging from developmental considerations of clonality, principles of selection and evolution in clonal plants, a survey of clonality in algae, to potential implications of clonality for plant mating, and beyond. This part of the volume aims at presenting novel ideas and hypotheses, and at summarizing existing knowledge in previously under-researched areas, thereby providing directions for future research initiatives.

This book captures ongoing cutting-edge research in the field of clonal plant ecology and evolution. It is directed to anyone from the undergraduate to specialist level who is interested in the biology of the intriguing phenomenon of asexual propagation in plants.

The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.

I Twenty-five years ago, at the Conference on the Comparative Reception of Darwinism held at the University of Texas in 1972, only two countries of the Iberian world-Spain and Mexico-were represented.' At the time, it was apparent that the topic had attracted interest only as regarded the "mainstream" science countries of Western Europe, plus the United States. The Eurocentric bias of professional history of science was a fact. The sea change that subsequently occurred in the historiography of science makes 1972 appear something like the antediluvian era. Still, we would like to think that that meeting was prescient in looking beyond the mainstream science countries-as then perceived-in order to test the variation that ideas undergo as they pass from center to periphery. One thing that the comparative study of the reception of ideas makes abundantly clear, however, is the weakness of the center/periphery dichotomy from the perspective of the diffusion of scientific ideas. Catholics in mainstream countries, for example, did not handle evolution much better than did their corre1igionaries on the fringes. Conversely, Darwinians in Latin America were frequently better placed to advance Darwin's ideas in a social and political sense than were their fellow evolutionists on the Continent. The Texas meeting was also a marker in the comparative reception of scientific ideas, Darwinism aside. Although, by 1972, scientific institutions had been studied comparatively, there was no antecedent for the comparative history of scientific ideas.