The aim of this edited book is to provide health professionals, across a wide variety of specialisms, with a targeted access to evolutionary medicine. Throughout the book, the views of both medical and evolutionary scientists on the latest relevant research is presented with a focus on practical implications. The inclusion of boxes explaining the theoretical background as well as both a glossary for technical terms and a lay summary for non- specialists enable medical researchers, public health professionals, policy makers, physicians, students, scholars and the public alike to quickly and easily access appropriate information. This edited volume is thus relevant to anyone keen on finding out how evolutionary medicine can improve the health and well-being of people.

Bone is ubiquitous and versatile, and uniquely repairs itself without scarring. However, we rarely see bone in its living state-and even then, mostly in two-tone images that only hint at its marvels. After it serves and protects vertebrate lives, bone reveals itself in surprising ways, sometimes hundreds of millions of years later. In Bones, orthopaedic surgeon Roy Meals explores and extols this amazing material that both supports and records vertebrate life. He demystifies the biological makeup of bones; how they grow, break and heal; and how medical innovations-from the first X-rays to advanced surgical techniques-enhance our lives. With enthusiasm and humour, Meals also reveals the enduring presence of bone outside the body-as fossils, ossuaries, tools, musical instruments-and celebrates allusions to bone in history, religion and idiom. Approachable and entertaining, Bones richly illuminates our bodies' essential framework.

An extremely well-organized, conceptually clear, empirically informed, and carefully argued volume...What makes this contribution special is the invigorating infusion of a wealth of principles and knowledge derived from evolutionary biology, neurophysiology, and cognitive science...The chapters provide abundant material for animated discussion.'' --- Evolution and Human Behavior, September 1997 When engaging in laboratory and field studies, researchers have an extensive set of implicit assumptions that justifies their research. However, these assumptions are rarely made explicit either to the researchers themselves, to their colleagues, or to the public. In this fascinating volume, the author gives insight into these underlying beliefs that scientists have regarding moral and biological issues involved in human life-such as decisions that influence reproductive practices, the termination of life, and the pursuit of biomedical research. He then uses this descriptive base to develop an ethic based on rational liberalism. His arguments stem from the thinking of biologists, moral philosophers, cognitive scientists, and social and developmental psychologists.

The past decade has witnessed an explosion of our knowledge on the structure, coding capacity and evolution of the genomes of the two DNA-containing cell organelles in plants: chloroplasts (plastids) and mitochondria. Comparative genomics analyses have provided new insights into the origin of organelles by endosymbioses and uncovered an enormous evolutionary dynamics of organellar genomes. In addition, they have greatly helped to clarify phylogenetic relationships, especially in algae and early land plants with limited morphological and anatomical diversity. This book, written by leading experts, summarizes our current knowledge about plastid and mitochondrial genomes in all major groups of algae and land plants. It also includes chapters on endosymbioses, plastid and mitochondrial mutants, gene expression profiling and methods for organelle transformation. The book is designed for students and researchers in plant molecular biology, taxonomy, biotechnology and evolutionary biology.

Marker-assisted plant breeding involves the application of molecular marker techniques and statistical and bioinformatics tools to achieve plant breeding objectives in a cost-effective and time-efficient manner. This book is intended for beginners in the field who have little or no prior exposure to molecular markers and their applications, but who do have a basic knowledge of genetics and plant breeding, and some exposure to molecular biology. An attempt has been made to provide sufficient basic information in an easy-to-follow format, and also to discuss current issues and developments so as to offer comprehensive coverage of the subject matter. The book will also be useful for breeders and research workers, as it offers a broad range of up-to-the-year information, including aspects like the development of different molecular markers and their various applications. In the first chapter, the field of marker-assisted plant breeding is introduced and placed in the proper perspective in relation to plant breeding. The next three chapters describe the various molecular marker systems, while mapping populations and mapping procedures including high-throughput genotyping are discussed in the subsequent five chapters. Four chapters are devoted to various applications of markers, e.g. marker-assisted selection, genomic selection, diversity analysis, finger printing and positional cloning. In closing, the last two chapters provide information on relevant bioinformatics tools and the rapidly evolving field of phenomics.

This is the first book on "phylogenetic supertrees," a recent, but controversial development for inferring evolutionary trees. Rather than analyze the combined primary character data directly, supertree construction proceeds by combining the tree topologies derived from those data. This difference in strategy has allowed for the exciting possibility of larger, more complete phylogenies than are otherwise currently possible, with the potential to revolutionize evolutionarily-based research. This book provides a comprehensive look at supertrees, ranging from the methods used to build supertrees to the significance of supertrees to bioinformatic and biological research. Reviews of many the major supertree methods are provided and four new techniques, including a Bayesian implementation of supertrees, are described for the first time. The far-reaching impact of supertrees on biological research is highlighted both in general terms and through specific examples from diverse clades such as flowering plants, even-toed ungulates, and primates. The book also critically examines the many outstanding challenges and problem areas for this relatively new field, showing the way for supertree construction in the age of genomics. Interdisciplinary contributions from the majority of the leading authorities on supertree construction in all areas of the bioinformatic community (biology, computer sciences, and mathematics) will ensure that this book is a valuable reference with wide appeal to anyone interested in phylogenetic inference.

The extended continental South American turtle record (Norian to Lujanian) allows us to follow the evolution of this reptile clade from its origins. Several significant stem turtle taxa such as: Palaeochersis talampayensis and Condorchelys antiqua provide information on the first steps of turtle evolution. Others such as: Chubutemys copelloi or Patagoniaemys gasparinae provide clues to the origin of the bizarre horned tortoises of the clade Meiolaniidae. The panpleurodiran species such as Notoemys laticentralis or Notoemys zapatocaensis shed light on the origin of modern pleurodiran turtles. This book explores aquatic and terrestrial cryptodiran turtles, South Gondwana pleurodiran turtles, North Gondwana pleurodiran turtles; Meiolaniforms and early differentiation of Mesozoic turtles.

How better than to mark the 150th anniversary of Darwin's book on human evolution than by challenging his theory with an updated version which instead places the female species at the centre of the theory. Sexual selection may have created us, but by refusing to take a good hard look at ourselves and our impact on the planet, we may be granting natural selection the power to eliminate us. A fascinating book which is both controversial and entertaining and which will deepen your understanding of human evolution like you would never have imagined. Heather deepens our understanding of human evolution by including genetic discoveries that were unavailable in 1871 when Darwin wrote The Descent of Man and Selection in Relation to Sex. She offers an updated version of the theory by viewing the courtship dance through a female lens. Darwin was correct in acknowledging that sexual selection is driven by female choice, but he was seriously mistaken in granting a female no active influence and depicting her as passively succumbing to the charms of the triumphant male who had bested another in a competition to win her favour or to the one who had tickled her fancy with his feathers. In the process of her doctoral research, Heather analysed hundreds of hours of tape-recorded interviews in which women identified the traits that made specific men in their lives sexually and reproductively attractive. Their insights help us make sense of recent studies that leave researchers scratching their heads when the species they study don't appear to be playing by the rules, according to Darwin. We are in the midst of two immediate existential crises-climate change and growing economic inequality-caused by human behaviour. If we are to be successful in addressing these challenges, Remoff argues that we need to come to terms with the double-edged sword at the heart of all that makes us special. Who are we? What selection pressures forged our species specific traits? Of all the trillions of species that have ever existed on this planet only one, Homo sapiens, has mastered language, the art of symbolic communication. Did female passions play a role in triggering our way with words? Absolutely. Our choice of reproductive partners shaped not only language ability but also many of the other traits that define us today.

This unique reference offers a discussion of the social and legal history behind the ongoing evolution versus creationism controversy. Evolution in the Courtroom: A Reference Guide chronicles the legal history of the evolution/creation debate sparked by Charles Darwin's publication On the Origin of Species by Means of Natural Selection in 1859. The first seven chapters provide a detailed historical overview of the debate, reviewing all of the major court cases with particular emphasis on the infamous Scopes "Monkey Trial" which pitted fundamentalist William Jennings Bryan against ACLU defense attorney Clarence Darrow, and became the standard to which all subsequent evolution trails have been compared. Ensuing discussions of the rise and fall of creationism as a science and the failure of "balanced treatment" in public schools culminate in a summary of skirmishes over the last decade. Profiles of scientists, politicians, clergy, and other influential people from Galileo to Frank White, the Arkansas governor who signed the equal time law without ever reading it, reveal fascinating facts and perspectives on both sides of the controversy. Detailed chronology of the history of the debate from Aristotle in 310 B.C. to the U.S. Senate's adoption of "Sense of the Senate" in June 2002 Biographies of 172 key individuals on both sides of the controversy, including Leona Wilson, who initiated the first lawsuit by creationists An edited collection of the eight principal court decisions, including Mclean v. Arkansas and Segraves v. State of California Photographs and illustrations of influential people like Herbert Spencer, who coined the terms "evolution" and "survival of the fittest"

Papers presented at the 20th meeting of the International Ornithological Congress held in New Zealand, December 1990 emphasizing New Zealand and the southern Pacific Ocean. Topics include: a summary of ornithological work in New Zealand, enemy recognition and response, parasitism and sexual selectio

Current Ornithology publishes authoritative, up-to-date, scholarly reviews of topics selected from the full range of current research in avian biology. Topics cover the spectrum from the molecular level of organization to population biology and community ecology. The series seeks especially to review (1) fields in which an abundant recent literature will benefit from synthesis and organization, or (2) newly emerging fields that are gaining recognition as the result of recent discoveries or shifts in perspective, or (3) fields in which students of vertebrates may benefit from comparisons of birds with other classes. All chapters are invited, and authors are chosen for their leadership in the subjects under review.

Philosophers have traditionally concentrated on the qualities that make human beings different from other species. In Beast and Man Mary Midgley, one of our foremost intellectuals, stresses continuities. What makes people tick? Largely, she asserts, the same things as animals. She tells us humans are rather more like other animals than we previously allowed ourselves to believe, and reminds us just how primitive we are in comparison to the sophistication of many animals. A veritable classic for our age, Beast and Man has helped change the way we think about ourselves and the world in which we live.

`A graceful, refreshing and enlightening book, applied philosophy that is relevant, timely and metaphysical in the best sense.' - New York Times Book Review

'Midgley is one of the most acute and penetrating voices in current moral philosophy. Her great gift is clarity, both of thought and, especially, of expression. To follow her reasoning is like watching a ballet dancer walking in the street: there is a litheness, a gracefulness, an ease of articulation, which attest to years of learning lightly worn.' - John Banville, Irish Times

An Open Letters Review Best Book of the Year A leading expert in animal behavior takes us into the wild to better understand and manage our fears. Fear, honed by millions of years of natural selection, kept our ancestors alive. Whether by slithering away, curling up in a ball, or standing still in the presence of a predator, humans and other animals have evolved complex behaviors in order to survive the hazards the world presents. But, despite our evolutionary endurance, we still have much to learn about how to manage our response to danger. For more than thirty years, Daniel Blumstein has been studying animals’ fear responses. His observations lead to a firm conclusion: fear preserves security, but at great cost. A foraging flock of birds expends valuable energy by quickly taking flight when a raptor appears. And though the birds might successfully escape, they leave their food source behind. Giant clams protect their valuable tissue by retracting their mantles and closing their shells when a shadow passes overhead, but then they are unable to photosynthesize, losing the capacity to grow. Among humans, fear is often an understandable and justifiable response to sources of threat, but it can exact a high toll on health and productivity. Delving into the evolutionary origins and ecological contexts of fear across species, The Nature of Fear considers what we can learn from our fellow animals—from successes and failures. By observing how animals leverage alarm to their advantage, we can develop new strategies for facing risks without panic.

Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.

This volume provides insight into gibbon diet and community ecology, the mating system and reproduction, and conservation biology, all topics which represent areas of substantial progress in understanding socio-ecological flexibility and conservation needs of the hylobatid family. This work analyzes hylobatid evolution by synthesizing recent and ongoing studies of molecular phylogeny, morphology, and cognition in a framework of gibbon and siamang evolution. With its clearly different perspective, this book is written to be read, referenced, and added to the bookshelves of scientists, librarians, and the interested public.

How did life begin on the early Earth? We know that life today is driven by the universal laws of chemistry and physics. By applying these laws over the past ?fty years, en- mous progress has been made in understanding the molecular mechanisms that are the foundations of the living state. For instance, just a decade ago, the ?rst human genome was published, all three billion base pairs. Using X-ray diffraction data from crystals, we can see how an enzyme molecule or a photosynthetic reaction center steps through its catalytic function. We can even visualize a ribosome, central to all life, translate - netic information into a protein. And we are just beginning to understand how molecular interactions regulate thousands of simultaneous reactions that continuously occur even in the simplest forms of life. New words have appeared that give a sense of this wealth of knowledge: The genome, the proteome, the metabolome, the interactome. But we can't be too smug. We must avoid the mistake of the physicist who, as the twentieth century began, stated con?dently that we knew all there was to know about physics, that science just needed to clean up a few dusty corners. Then came relativity, quantum theory, the Big Bang, and now dark matter, dark energy and string theory. Similarly in the life sciences, the more we learn, the better we understand how little we really know. There remains a vast landscape to explore, with great questions remaining.

This book presents a detailed examination of the current state of knowledge in the field of paleoneurology in the main amniote groups (reptiles, birds and mammals), and advances resulting from new non-invasive technologies. The study of fossil endocasts is an area of considerable current interest, and has long been central to our understanding of the evolution of the brain, development of senses and behavioral adaptations in diverse vertebrate groups and across vertebrates as a whole. Recent advances in non-invasive imaging have significantly increased the number of fossil taxa for which brain morphology is known, and it may now be possible to quantitatively analyze the relative size of brain regions. Providing a general overview of current perspectives and problems in evolutionary neuroanatomy, this book is intended for a wide range of readers, including undergraduate and graduate students, teachers, and anyone with a special interest in paleoneurology. It is also useful as supplementary reading for courses in digital anatomy, vertebrate comparative anatomy, computed morphometrics, paleontology, neurology and radiology as well as evolution programs

Intelligence allows people to understand events and to shape their surrounding environment. This book delves deeper into the theories and applications of intelligence, showing it is a multifaceted concept -defined and explained differently by prestigious experts of various disciplines in their own research. The book provides interdisciplinary connections of intelligence as it relates to a variety of clearly outlined subject areas, and should lead to a deep understanding of the phenomenon as it pertains to practical applications in different domains. Contributors in this volume present results from evolutionary biology, mathematics, artificial intelligence, medicine, psychology, cultural studies, economy, political sciences and philosophy. Individual scientific models are integrated in an interdisciplinary concept of wisdom. This volume will help enhance the common understanding of intelligence for fellow researchers and scientists alike.

Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

Evolutionary Psychiatry challenges a medical model which has supplied few effective answers to long-standing conundrums. A comprehensive introduction to the new science of Darwinian Psychiatry, this second edition includes important fresh material on a number of disorders, along with an entirely new chapter on research.
Anthony Stevens and John Price argue that psychiatric symptoms are manifestations of ancient adaptive strategies which are no longer necessarily appropriate but which can best be understood and treated in an evolutionary and developmental context. Particularly important are the Stevens and Price propose to account for the worldwide existence of mood disorders and schizophrenia, as well as offering solutions for such puzzles as paedophilia, sado masochism and the function of dreams.
Readily accessible to both the specialist and non-specialist reader, Evolutionary Psychiatry describes in detail the disorders and conditions commonly encountered in psychiatric practice and shows how evolutionary theory can account for their biological origins and functional nature.

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This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture. Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA in osmoregulation, desert-adapted mammals, the giraffe kidney, mosquito Malpighian tubules, and circadian rhythms. The book highlights how different approaches to explaining the same physiological processes greatly increase our understanding of these fundamental processes. Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve our overall grasp of the mechanisms of sodium and water balance.