This book presents cutting edge methods that provide insights into the pathways by which salt and water traverse cell membranes and flow in an orchestrated fashion amongst the many compartments of the body. It focuses on a number of molecular, cellular and whole animal studies that involve multiple physiological systems and shows how the internal milieu is regulated by multifactorial gene regulation, molecular signaling, and cell and organ architecture. Topics covered include: water channels, the urinary concentrating mechanism, angiotensin, the endothelin system, miRNAs and MicroRNA in osmoregulation, desert-adapted mammals, the giraffe kidney, mosquito Malpighian tubules, and circadian rhythms. The book highlights how different approaches to explaining the same physiological processes greatly increase our understanding of these fundamental processes. Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve our overall grasp of the mechanisms of sodium and water balance.

‘Steve Brusatte, the author of The Rise and Fall of the Dinosaurs, brings mammals out from the shadow of their more showy predecessors in a beautifully written book that . . . makes the case for them as creatures who are just as engaging as dinosaurs.’ – The Sunday Times, ‘Best Books For Summer’ 'In this terrific new book, Steve Brusatte . . . brings well-known extinct species, the sabre-toothed tigers and the woolly mammoths, thrillingly back to life' – The Times The passing of the age of the dinosaurs allowed mammals to become ascendant. But mammals have a much deeper history. They – or, more precisely, we – originated around the same time as the dinosaurs, over 200 million years ago; mammal roots lie even further back, some 325 million years. Over these immense stretches of geological time, mammals developed their trademark features: hair, keen senses of smell and hearing, big brains and sharp intelligence, fast growth and warm-blooded metabolism, a distinctive line-up of teeth (canines, incisors, premolars, molars), mammary glands that mothers use to nourish their babies with milk, qualities that have underlain their success story. Out of this long and rich evolutionary history came the mammals of today, including our own species and our closest cousins. But today’s 6,000 mammal species - the egg-laying monotremes including the platypus, marsupials such as kangaroos and koalas that raise their tiny babies in pouches, and placentals like us, who give birth to well-developed young – are simply the few survivors of a once verdant family tree, which has been pruned both by time and mass extinctions. In The Rise and Reign of the Mammals, palaeontologist Steve Brusatte weaves together the history and evolution of our mammal forebears with stories of the scientists whose fieldwork and discoveries underlie our knowledge, both of iconic mammals like the mammoths and sabre-toothed tigers of which we have all heard, and of fascinating species that few of us are aware of. For what we see today is but a very limited range of the mammals that have existed; in this fascinating and ground-breaking book, Steve Brusatte tells their – and our – story.

This book offers a comprehensive exploration of the major key concepts common to economics and evolutionary biology. Written by a group of philosophers of science, biologists and economists, it proposes analyses of the meaning of twenty-five concepts from the viewpoint respectively of economics and of evolutionary biology -each followed by a short synthesis emphasizing major discrepancies and commonalities. This analysis is surrounded by chapters exploring the nature of the analogy that connects evolution and economics, and chapters that summarize the major teachings of the analyses of the keywords. Most scholars in biology and in economics know that their science has something in common with the other one, for instance the notions of competition and resources. Textbooks regularly acknowledge that the two fields share some history - Darwin borrowing from Malthus the insistence on scarcity of resources, and then behavioral ecologists adapting and transforming game theory into evolutionary game theory in the 1980s, while Friedman famously alluded to a Darwinian process yielding the extant firms. However, the real extent of the similarities, the reasons why they are so close, and the limits and even the nature of the analogy connecting economics and biological evolution, remain inexplicit. This book proposes basis analyses that can sustain such explication. It is intended for researchers, grad students and master students in evolutionary and in economics, as well as in philosophy of science.

Evolutionary Psychiatry challenges a medical model which has supplied few effective answers to long-standing conundrums. A comprehensive introduction to the new science of Darwinian Psychiatry, this second edition includes important fresh material on a number of disorders, along with an entirely new chapter on research.
Anthony Stevens and John Price argue that psychiatric symptoms are manifestations of ancient adaptive strategies which are no longer necessarily appropriate but which can best be understood and treated in an evolutionary and developmental context. Particularly important are the Stevens and Price propose to account for the worldwide existence of mood disorders and schizophrenia, as well as offering solutions for such puzzles as paedophilia, sado masochism and the function of dreams.
Readily accessible to both the specialist and non-specialist reader, Evolutionary Psychiatry describes in detail the disorders and conditions commonly encountered in psychiatric practice and shows how evolutionary theory can account for their biological origins and functional nature.

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Darwin's idea has been called the best idea anyone ever had. In Interrogations of Evolutionism in German Literature 1859-2011 Nicholas Saul offers the first representative account of German literary responses to Darwinian evolutionism from Raabe and Jensen via Ernst Junger and Botho Strauss to Dietmar Dath. Often identified with National Socialist ideology and hence notably absent from the public sphere after 1945, Darwinian thought is in fact shown to be distorted though the lens of Social Darwinism and bionationalist organicism. As Nicholas Saul shows, literature has been the main agent in public discourse for challenging such illiberal presentations, and there is a common thread of salvific individualism which leads to the new legitimacy of Darwinian discourse today.

This book is a socio-philosophical journey across several aspects of our society's focus on individual freedom, taking cues from some of the most prominent thinkers of our time. The auhtor posits that the human quest for freedom (mostly dominated by the Western culture but by no means confined to the West) has reached its ultimate paradox of making contemporary humans fundamentally unable to act as ecosystems (thus cooperate and collaborate). They have become egosystems, completely centred on the attainment of their own individual satisfaction. The author sees this as the culmination of a rightful quest for self-affirmation, which has been a key driver of progress across human history and by no means a negative one. But the paradox is that such a human-centred notion of freedom and individual accomplishment results in a much reduced ability to operate in sync with others, at the time when mankind would need more cooperation, collaboration and selflessness to address the key challenges it faces (from climate change to inequalities). Through the examination of the broad and interdisciplinary themes typical of social philosophy and the most recent cultural studies, in direct confrontation with the thought of authors such as Lipovetsky and Bauman, Lasch and Beck, Ehrenberg and Han, this book examines shifts in cultural norms at the possible end of a millenary civilization.

Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

In this new fourth edition, Campbell has revised and updated his classic introduction to the field. "Human Evolution "synthesizes the major findings of modern research and theory and presents a complete and integrated account of the evolution of human beings. New developments in microbiology and recent fossil records are incorporated into the enormous range of this volume, with the resulting text as lucid and comprehensive as earlier editions. The fourth edition retains the thematic structure and organization of the third, with its cogent treatment of human variability and speciation, primate locomotion, and nonverbal communication and the evolution of language, supported by more than 150 detailed illustrations and an expanded and updated glossary and bibliography. As in prior editions, the book treats evolution as a concomitant development of the main behavioral and functional complexes of the genus "Homo" - among them motor control and locomotion, mastication and digestion, the senses and reproduction. It analyzes each complex in terms of its changing function, and continually stresses how the separate complexes evolve "interdependently" over the long course of the human journey. All these aspects are placed within the context of contemporary evolutionary and genetic theory, analyses of the varied extensions of the fossil record, and contemporary primatology and comparative morphology. The result is a primary text for undergraduate and graduate courses, one that will also serve as required reading for anthropologists, biologists, and nonspecialists with an interest in human evolution.

After volume 33, this book series was replaced by the journal "Evolutionary Biology." Please visit www.springer.com/11692 for further information.

The nature of science is to work on the boundaries between the known and the unknown. These boundaries shift as new methods are developed and as new concepts are elaborated (e.g., the theory of the gene, or more recently, the coalescence framework in population genetics). These tools allow us to address questions that were previously outside the realm of science, and, as a consequence, the boundary between the knowable and unknowable has shifted. A study of limits should reveal and clarify the boundaries and make sharper the set of questions. This book examines and analyzes these new limits as they are applied to evolutionary biology and population genetics. It does this by framing the analysis within four major classes of problems - establishing the fact of evolution; understanding the evolutionary pathways that led to today's biological world; mechanisms of evolutionary change (e.g., models of social behavior, sexual selection, macro evolution); and, finally, prediction.

After volume 33, this book series was replaced by the journal "Evolutionary Biology." Please visit www.springer.com/11692 for further information. In Volume 29, internationally acclaimed researchers address a broadrange of topics including the organization of eukaryotic genes, evolution of Drosophila mating systems, and evolutionary-developmental approaches to fin/limb transformation.

Astrobiology is a very broad interdisciplinary field covering the origin, evolution, distribution, and destiny of life in the universe, as well as the design and implementation of missions for solar system exploration. A review covering its complete spectrum has been missing at a level accessible even to the non-specialist.
The last section of the book consists of a supplement, including a glossary, notes, and tables, which represent highly condensed windows' into research ranging from basic sciences to earth and life sciences, as well as the humanities.
These additions should make The New Science of Astrobiology accessible to a wide readership: scientists, humanists, and the general reader will have an opportunity to participate in one of the most rewarding activities of contemporary culture.

What a pity it would have been if biologists had refused to accept Darwin's theory of natural selection, which has been essential in helping biologists understand a wide range of phenomena in many animal species. These days, to study any animal species while refusing to consider the evolved adaptive significance of their behavior would be considered pure folly--unless, of course, the species is "homo sapiens." Graduate students training to study this particular primate species may never take a single course in evolutionary theory, although they may take two undergraduate and up to four graduate courses in statistics. These methodologically sophisticated students then embark on a career studying human aggression, cooperation, mating behavior, family relationships, or altruism with little or no understanding of the general evolutionary forces and principles that shaped the behaviors they are investigating. This book hopes to redress that wrong.
It is one of the first to apply evolutionary theories to mainstream problems in personality and social psychology that are relevant to a wide range of important social phenomena, many of which have been shaped and molded by natural selection during the course of human evolution. These phenomena include selective biases that people have concerning how and why a variety of activities occur. For example:
* information exchanged during social encounters is initially perceived and interpreted;
* people are romantically attracted to some potential mates but not others;
* people often guard, protect, and work hard at maintaining their closest relationships;
* people form shifting and highly complicated coalitions with kin and close friends; and
* people terminate close, long-standing relationships.
"Evolutionary Social Psychology" begins to disentangle the complex, interwoven patterns of interaction that define our social lives and relationships.

Why are humans everywhere prone to believe in ghosts?
How might our tendency to imitate one another be contributing to the climate catastrophe?
And does our deep evolutionary past impel us to vote for strongmen?

In 1987, Harvey Whitehouse went to live with an indigenous community deep in the Papua New Guinea rainforest. His experiences there convinced him that, far from being wildly different, humans are fundamentally alike: their beliefs and behaviours rooted in a set of evolutionary urges that can be found in any society, anywhere.

Here, Whitehouse roves across twelve millennia and five continents to uncover how these evolved urges have both shaped and been reshaped by human history. Along the way, he shows that this ancient inheritance does not just hold the key to explaining the modern world – but perhaps also to changing it.

This text incorporates modern molecular knowledge of the structure and regulation of genes into an evolutionary framework, stressing the importance of genomic integration as a selectable feature in the evolution of multicellular phenotypes. It reinterprets important subjects in the new framework, including transposable elements, epigenetics, the evolution of sex, phenotypic plasticity and the evolution and regulation of longevity assurance systems.

Graeme Snooks has set himself the ambitious and original task of exploring the driving force of global change over the past 2 million years. The book outlines and explains the biological development of life, going on to develop a fully dynamic model, not just of genetic change, but of the broader process of life on earth. Snooks also provides a critical review of current interpretations about the course of history and the forces driving it. Finally, he develops an entirely new interpretation of the dynamics of human society, arguing that the rise and fall of societies is an outcome of the development and exhaustion of these strategies.
This dynamic strategy model is employed to discuss likely future outcomes for society. Controversially, Snooks argues that far from leading to ecological destruction, growth--including technological change--is both natural and necessary. "The Dynamic Society" demonstrates that dynamism, not stasis, is the essential condition of human society, as it is of life.

In this book Graeme Snooks has set himself the highly ambitious task of exploring the driving force of global change over the past 2 million years. The author also employs his dynamic strategy model to discuss future outcomes for human society, controversially arguing that far from leading to ecological destruction, growth-inducing technological change is both necessary and liberating. Ultimately, the book demonstrates that dynamism, not stasis, is the essential condition of human society, as it is of life.

The book presents a re-reading of H. G. Wells' novel "The Island of Doctor Moreau" as a key to addressing the controversies of our own humanity. Ron Edwards is a broadly-experienced researcher and teacher specializing in evolutionary theory, as well as a long-time participant in animal care oversight at a leading research institution. His careful examination in this book looks strictly at the novel's actual story to rehabilitate it from the widespread distorted version, and argues that the real story provides an outstanding means to confront human exceptionalism, a prevailing stopping-point for science and ethics. It integrates literature, history, and science; it bluntly criticizes, discloses, and advocates; and it combines accuracy with clarity, directed toward a lay audience. Finally, the book also raises a genuinely new and relevant issue: with human exceptionalism abolished, where do ethics come from?

Intelligence allows people to understand events and to shape their surrounding environment. This book delves deeper into the theories and applications of intelligence, showing it is a multifaceted concept -defined and explained differently by prestigious experts of various disciplines in their own research. The book provides interdisciplinary connections of intelligence as it relates to a variety of clearly outlined subject areas, and should lead to a deep understanding of the phenomenon as it pertains to practical applications in different domains. Contributors in this volume present results from evolutionary biology, mathematics, artificial intelligence, medicine, psychology, cultural studies, economy, political sciences and philosophy. Individual scientific models are integrated in an interdisciplinary concept of wisdom. This volume will help enhance the common understanding of intelligence for fellow researchers and scientists alike.

Mitochondrial Eve and Y-Chromosomal Adam discusses theoretical ideas, interpretations, and paleontological evidence to narrate the origin and evolutionary story of Sapiens through the transitional stages of archaic human species involved in the evolutionary pilgrimage, from the great apes and to modern humans. Author Subir Ranjan Kundu investigates the DNA footprints of primates - great apes, archaic humans, and anatomically modern human beings - to stretch out the missing links between evolutionary milestones to define and redefine the progress of life. The origin and evolution of Humans have always remained a source of debate between the creationists and evolutionists, in terms of recognizing the results of such researches on biological evolution and its credible interpretation of the evolutionists who upheld the origin and evolution of "Sapiens" resulting from great apes in course of the gradual evolutionary progress of life. Kundu analyzes interpretations of molecular and evolutionary geneticists over the last four decades and presents detailed illustrations on the matrilineal inheritance of mitochondrial DNA (represented by mitochondrial Eve as primordial mother), patrilineal inheritance of Y-chromosomal DNA (represented by Y-chromosomal Adam as primordial father). He also presents elaborate structural aspects of the human genome and molecular aspects of the DNA footprint of Sapiens. This book is addressed to heterogeneous readers, graduate, and post-graduate students, research scientists and the general public interested in the origins and biological evolution of humans in view of molecular phylogenetics.

In this "wonderful" (John Brandon, Forbes) book, neuroscientist Shane O'Mara invites us to marvel at the benefits walking confers on our bodies and brains, and to appreciate the advantages of this uniquely human skill. From walking's evolutionary origins, traced back millions of years to life forms on the ocean floor, to new findings from cutting-edge research, he reveals how the brain and nervous system give us the ability to balance, weave through a crowded city, and run our "inner GPS" system. Walking is good for our muscles and posture;?it helps to protect and repair organs, and can slow or turn back the aging of our brains. With our minds in motion we think more creatively, our mood improves, and stress levels fall. Walking together to achieve a shared purpose is also a social glue that has contributed to our survival as a species. As our lives become increasingly sedentary, O'Mara makes the case that we must start walking again-whether it's up a mountain, down to the park,?or simply to school and work. In Praise of Walking?illuminates the joys, health benefits, and mechanics of walking, and reminds us to get out of our chairs and discover a happier, healthier, more creative self.