This book adopts an experimental approach to understanding the mechanisms of evolution and the nature of evolutionary processes, with examples drawn from microbial, plant and animal systems. It incorporates insights from remarkable recent advances in theoretical modeling, and the fields of molecular genetics and environmental genomics.
Adaptation is caused by selection continually winnowing the genetic variation created by mutation. In the last decade, our knowledge of how selection operates on populations in the field and in the laboratory has increased enormously, and the principal aim of this book is to provide an up-to-date account of selection as the principal agent of evolution. In the classical Fisherian model, weak selection acting on many genes of small effect over long periods of time is responsible for driving slow and gradual change. However, it is now clear that adaptation in laboratory populations often involves strong selection acting on a few genes of large effect, while in the wild selection is often strong and highly variable in space and time. Indeed these results are changing our perception of how evolutionary change takes place. This book summarizes our current understanding of the causes and consequences of selection, with an emphasis on quantitative and experimental studies. It includes the latest research into experimental evolution, natural selection in the wild, artificial selection, selfish genetic elements, selection in social contexts, sexual selection, and speciation.
Selection: The Mechanism of Evolution is an advanced textbook suitable for senior undergraduate and graduate students taking courses in evolutionary biology, ecology, populationgenetics, and experimental evolution. It will also be a valuable reference tool for those professional researchers in these fields requiring an authoritative and up-to-date overview of the topic, as well as providing an accessible treatment of evolutionary mechanisms for molecular and cellular biologists.

Even before the publication of Darwin's Origin of Species, the perception of evolutionary change has been a tree-like pattern of diversification - with divergent branches spreading further and further from the trunk. In the only illustration of Darwin's treatise, branches large and small never reconnect. However, it is now evident that this view does not adequately encompass the richness of evolutionary pattern and process. Instead, the evolution of species from microbes to mammals builds like a web that crosses and re-crosses through genetic exchange, even as it grows outward from a point of origin. Some of the avenues for genetic exchange, for example introgression through sexual recombination versus lateral gene transfer mediated by transposable elements, are based on definably different molecular mechanisms. However, even such widely different genetic processes may result in similar effects on adaptations (either new or transferred), genome evolution, population genetics, and the evolutionary/ecological trajectory of organisms. For example, the evolution of novel adaptations (resulting from lateral gene transfer) leading to the flea-borne, deadly, causative agent of plague from a rarely-fatal, orally-transmitted, bacterial species is quite similar to the adaptations accrued from natural hybridization between annual sunflower species resulting in the formation of several new species. Thus, more and more data indicate that evolution has resulted in lineages consisting of mosaics of genes derived from different ancestors. It is therefore becoming increasingly clear that the tree is an inadequate metaphor of evolutionary change. In this book, Arnold promotes the 'web-of-life' metaphoras a more appropriate representation of evolutionary change in all lifeforms.

Leading researchers in the area of the origin and evolution of life in the universe contributed to Chemical Evolution: Physics of the Origin and Evolution of Life. This volume provides a review of this interdisciplinary field. In 35 chapters many aspects of the origin of life are discussed by 90 authors, with particular emphasis on the early paleontological record: physical, chemical, biological, and informational aspects of life's origin, instrumentation in exobiology and system exploration; the search for habitable planets and extraterrestrial intelligent radio signals. This book contains the proceedings of the Fourth Trieste Conference on Chemical Evolution that took place in September 1995, in which scientists from a wide geographical distribution joined in a Memorial to Cyril Ponnamperuma, who was a pioneer in the field of chemical evolution, the origin of life, and exobiology, and also initiated the Trieste Conferences on Chemical Evolution and the Origin of Life. This fourth Conference was therefore dedicated to his memory. Audience: Graduate students and researchers in the many areas of basic, earth, and life sciences that contribute to the study of chemical evolution and the origin of life.

Understanding of animal social and sexual evolution has seen a renaissance in recent years with discoveries of frequent infidelity in apparently monogamous species, the importance of sperm competition, active female mate choice, and eusocial behavior in animals outside the traditional social insect groups. Each of these findings has raised new questions, and suggested new answers, about the evolution of behavioral interactions among animals. This volume synthesizes recent research on the sexual and social biology of the Crustacea, one of the dominant invertebrate groups on earth. Its staggering diversity includes ecologically important inhabitants of nearly every environment from deep-sea trenches, through headwater streams, to desert soils. The wide range of crustacean phenotypes and environments is accompanied by a comparable diversity of behavioral and social systems, including the elaborate courtship and wildly exaggerated morphologies of fiddler crabs, the mysterious queuing behavior of migrating spiny lobsters, and even eusociality in coral-reef shrimps. This diversity makes crustaceans particularly valuable for exploring the comparative evolution of sexual and social systems. Despite exciting recent advances, however, general recognition of the value of Crustacea as models has lagged behind that of the better studied insects and vertebrates. This book synthesizes the state of the field in crustacean behavior and sociobiology and places it in a conceptually based, comparative framework that will be valuable to active researchers and students in animal behavior, ecology, and evolutionary biology. It brings together a group of internationally recognized and rising experts in fields related to crustacean behavioral ecology, ranging from physiology and functional morphology, through mating and social behavior, to ecology and phylogeny. Each chapter makes connections to other, non-crustacean taxa, and the volume closes with a summary section that synthesizes the contributions, discusses anthropogenic impacts, highlights unanswered questions, and provides a vision for profitable future research.

Systematics has developed rapidly during the past two decades. A multitude of new methods and contributions from a diversity of biological fields including molecular genetics and developmental biology have provided a wealth of phylogenetic hypotheses, some confirming traditional views others contradicting them. Despite such inconsistencies, it is now possible to recognize robust regions of a 'tree of life' and also to identify problematic areas which have yet to be resolved. This is the first book to apply the current state of phylogeny to an evolutionary interpretation of animal organ systems and body architecture, providing alternative theories in those cases of continuing controversy.
Organs do not appear suddenly during evolution; instead they are composed of far simpler structures. In some cases it is even possible to trace particular molecules or physiological pathways as far back as pre-animal history. What emerges is a fascinating picture, showing how animals have combined ancestral and new elements in novel ways to form constantly changing responses to environmental requirements.
The Evolution of Organ Systems starts with a general overview of current animal phylogeny, followed by review of general body organization including symmetry, anteroposterior axis, dorsoventral axis, germ layers, segmentation, and skeletons. Subsequent chapters then provide a detailed description of the individual organ systems themselves - integument, musculature, nervous system, sensory organs, body cavities, excretory system, circulatory system, respiratory system, intestinal system, gonads and gametes. Generously illustrated throughout, this accessible text is suitable for both upper levelundergraduate and graduate students taking courses in animal evolution, organogenesis, animal anatomy, zoology and systematics. It will also be a valuable reference tool for those professional researchers in these fields requiring an authoritative, balanced and up-to-date overview of the topic.

This book takes a fresh look at the work, thoughts, and life of 1956 Nobel Prize winner William B. Shockley. It reconstructs Shockley's upbringing, his patriotic achievements during World War II, his contribution to semiconductor physics - culminating with the epoch-making invention of the transistor - and his views on the social issues of his time. The author's unparalleled access to Shockley's personal documents provides insight into a colorful, yet controversial, man, and also sheds light on the attitudes of other prominent scientists of that era. Shockley was not only an outstanding scientist in his own right but also a fiercely independent thinker in perpetual search of the truth. His contributions to the field known today as microelectronics are enormous and unmatched. This book explores the critical facets of Shockley's life, replete with never-before-published photos and excerpts from his private correspondence and personal notebooks. The book also delves into Shockley's views on genetics and human intelligence. It tells the story of a man beset by an unrelenting rationality, slandered by the popular media, and ultimately alienated by his peers. It discusses his controversial, although sometimes prescient, ideas regarding human genetics, putting these into the context of modern research findings. Today, William Shockley is perhaps just as enigmatic as his work and accomplishments. The author presents a convincing argument that Shockley still has much to say about the issues of our age, and many of his ideas deserve evaluation in the public forum.

The broad arc of islands north of Australia that extends from Indonesia east towards the central Pacific is home to a set of human populations whose concentration of diversity is unequaled elsewhere. Approximately 20% of the worlds languages are spoken here, and the biological and genetic heterogeneity among the groups is extraordinary. Anthropologist W.W. Howells once declared diversity in the region so Protean as to defy analysis. However, this book can now claim considerable success in describing and understanding the origins of the genetic and linguistic variation there. In order to cut through this biological knot, the authors have applied a comprehensive battery of genetic analyses to an intensively sampled set of populations, and have subjected these and complementary linguistic data to a variety of phylogenetic analyses. This has revealed a number of heretofore unknown ancient Pleistocene genetic variants that are only found in these island populations, and has also identified the genetic footprints of more recent migrants from Southeast Asia who were the ancestors of the Polynesians. The book lays out the very complex structure of the variation within and among the islands in this relatively small region, and a number of explanatory models are tested to see which best account for the observed pattern of genetic variation here. The results suggest that a number of commonly used models of evolutionary divergence are overly simple in their assumptions, and that often human diversity has accumulated in very complex ways.

Ancestral sequence reconstruction is a technique of growing importance in molecular evolutionary biology and comparative genomics. As a powerful tool for testing evolutionary and ecological hypotheses, as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a range of fields. Ancestral Sequence Reconstruction starts with a historical overview of the field, before discussing the potential applications in drug discovery and the pharmaceutical industry. This is followed by a section on computational methodology, which provides a detailed discussion of the available methods for reconstructing ancestral sequences (including their advantages, disadvantages, and potential pitfalls). Purely computational applications of the technique are then covered, including whole proteome reconstruction. Further chapters provide a detailed discussion on taking computationally reconstructed sequences and synthesizing them in the laboratory. The book concludes with a description of the scientific questions where experimental ancestral sequence reconstruction has been utilized to provide insights and inform future research. This research level text provides a first synthesis of the theories, methodologies and applications associated with ancestral sequence recognition, while simultaneously addressing many of the hot topics in the field. It will be of interest and use to both graduate students and researchers in the fields of molecular biology, molecular evolution, and evolutionary bioinformatics.

Originally published in 1920, this book contains the text of a series of lectures that were originally delivered to general audiences in Aberdeen in 1917 on the subject of the impact of humanity on the animal population of Scotland. Ritchie examines how the presence of man affected the local fauna, either through deliberate manipulation, such as domestication and hunting, or as an indirect effect of actions such as deforestation and animals conveyed to the area as parasites or hidden in imports. The text is illustrated with a number of plates showing the effects of certain types of animal life on the environment and various native Scottish animals. This book will be of value to anyone with an interest in the relationship between humanity and animals and the impact of human decisions on the environment.

This is the sixth volume of a ten-volume series on The Natural History of the Crustacea. The volume synthesizes in nineteen chapters our current understanding of diverse topics in crustacean reproductive biology. In the first part of this book, the chapters address allocation strategies to reproduction, gamete production, brooding behavior, and other components of parental care in crustaceans. The second part of the volume centers on sexual systems in crustaceans. The third section of the volume covers crustacean mating systems and sexual selection. Reproductive Biology ends with three chapters covering diverse topics including reproductive rhythms, crustacean personality research, and record breaking crustaceans with respect to reproductive characters.

The present book aims to examine how sexual selection works in the human species. Almost all scholarly effort focuses on sexual selection in non-human species and extrapolates the findings to the human one. However, human mating has a unique pattern not found in any other species, namely parental influence over mate choice. Across preindustrial societies, the typical pattern of long-term mating is arranged marriage, where parents choose spouses for their children. By doing so, parents effectively become a sexual selection force. Traits that enhance an individual's chance to be selected as a son- or a daughter-in-law confer important reproductive advantages to those who are endowed with them, increasing in frequency in the population. The author has coined the term parental choice to describe the sexual selection force that arises from parental control over mating. He synthesizes extensive theoretical and empirical work in order to understand and model this force. The aim is to understand which factors give rise to parental choice and to combine these insights into constructing a more formal model. It also aims to further examine whether the predictions of the model fit the patterns of mating found across different types of human societies, and how the model can be used to understand the evolution of behavioral traits involved in mating. By synthesizing the various arguments put forward and published across the literature, the book offers a comprehensive argument and overview of an aspect of sexual selection unique to our species. Furthermore, the book revises and extends previously made arguments and models, while it provides useful insights on how the proposed revision of sexual selection theory can enable us to understand a wide range of human behavioral phenomena. It should be key reading for those interested in studying sexual selection in general and in the Homo sapiens species in particular.

Does natural selection act primarily on individual organisms, on groups, on genes, or on whole species? Samir Okasha provides a comprehensive analysis of the debate in evolutionary biology over the levels of selection, focusing on conceptual, philosophical and foundational questions. A systematic framework is developed for thinking about natural selection acting at multiple levels of the biological hierarchy; the framework is then used to help resolve outstanding issues. Considerable attention is paid to the concept of causality as it relates to the levels of selection, in particular the idea that natural selection at one hierarchical level can have effects that 'filter' up or down to other levels. Unlike previous work in this area by philosophers of science, full account is taken of the recent biological literature on 'major evolutionary transitions' and the recent resurgence of interest in multi-level selection theory among biologists. Other biological topics discussed include Price's equation, kin and group selection, the gene's eye view, evolutionary game theory, outlaws and selfish genetic elements, species and clade selection, and the evolution of individuality. Philosophical topics discussed include reductionism and holism, causation and correlation, the nature of hierarchical organization, and realism and pluralism.

Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

We are interested in the evolution of hominin diets for several reasons. One is the fundamental concern over our present-day eating habits and the consequences of our societal choices, such as obesity prevalent in some cultures and starvation in others. Another is that humans have learned to feed themselves in extremely varied environments, and these adaptations, which are fundamentally different from those of our closest biological relatives, have to have had historical roots of varying depth. The third, and the reason why most paleoanthropologists are interested in this question, is that a species' trophic level and feeding adaptations can have a strong effect on body size, locomotion, "life history strategies," geographic range, habitat choice, and social behavior.
Diet is key to understanding the ecology and evolution of our distant ancestors and their kin, the early hominins. A study of the range of foods eaten by our progenitors underscores just how unhealthy many of our diets are today. This volume brings together authorities from disparate fields to offer new insights into the diets of our ancestors. Paleontologists, archaeologists, primatologists, nutritionists and other researchers all contribute pieces to the puzzle.
This volume has at its core four main sections:
DT Reconstructed diets based on hominin fossils--tooth size, shape, structure, wear, and chemistry, mandibular biomechanics
DT Archaeological evidence of subsistence--stone tools and modified bones
DT Models of early hominin diets based on the diets of living primates--both human and non-human, paleoecology, and energetics
DT Nutritional analyses and their implications for evolutionarymedicine
New techniques for gleaning information from fossil teeth, bones, and stone tools, new theories stemming from studies of paleoecology, and new models coming from analogy with modern humans and other primates all contribute to our understanding. When these approaches are brought together, they offer an impressive glimpse into the lives of our distant ancestors. The contributions in this volume explore the frontiers of our knowledge in each of these disciplines as they address the knowns, the unknowns, and the unknowables of the evolution of hominin diets.

This volume is part of the definitive edition of letters written by and to Charles Darwin, the most celebrated naturalist of the nineteenth century. Notes and appendixes put these fascinating and wide-ranging letters in context, making the letters accessible to both scholars and general readers. Darwin depended on correspondence to collect data from all over the world, and to discuss his emerging ideas with scientific colleagues, many of whom he never met in person. The letters are published chronologically: Volume 21 includes letters from 1873, the year in which Darwin received responses to his work on human and animal expression. Also in this year, Darwin continued his work on carnivorous plants and plant movement, finding unexpected similarities between the plant and animal kingdoms, raised a subscription for his friend Thomas Henry Huxley, and decided to employ a scientific secretary for the first time - his son Francis.

The claim that evolution undermines Christianity is standard fare in our culture. Indeed, many today have the impression that the two are mutually exclusive and that a choice must be made between faith and reason-rejecting Christianity on the one hand or evolutionary theory on the other. Is there a way to square advances in this field of study with the Bible and Church teaching? In this book-his fourth dedicated to applying Joseph Ratzinger/Benedict XVI's wisdom to pressing theological difficulties-Matthew Ramage answers this question decidedly in the affirmative. Distinguishing between evolutionary theory properly speaking and the materialist attitude that is often conflated with it, Ramage's work meets the challenge of evolutionary science to Catholic teaching on human origins, guided by Ratzinger's conviction that faith and evolutionary theory mutually enrich one another. Pope Benedict gifted the Church with many pivotal yet often-overlooked resources for engaging evolution in the light of faith, especially in those instances where he addressed the topic in connection with the Book of Genesis. Ramage highlights these contributions and also makes his own by applying Ratzinger's principles to such issues as the meaning of man's special creation, the relationship between sin and death, and the implications of evolution for eschatology. Notably, Ramage shows that many apparent conflicts between Christianity and evolutionary theory lose their force when we interpret creation in light of the Paschal Mystery and fix our gaze on Jesus, the New Adam who reveals man to himself. Readers of this text will find that it does more than merely help to resolve apparent contradictions between faith and modern science. Ramage's work shows that discoveries in evolutionary biology are not merely difficulties to be overcome but indeed gifts that yield precious insight into the mystery of God's saving plan in Christ.

Why are some kinds of organism species-rich and others species-poor? How do new species arise and why do some go extinct? Why do organisms grow and behave the way they do? This book provides an introduction to evolutionary ecology, the science that brings ecology and evolution together to help understand biological diversity. In a concise, readable format, Peter Mayhew covers the entire breadth of the subject, from life histories and the evolution of sex, to speciation and macroecology. Many emerging fields are also introduced, such as metabolic ecology, the evolution of population dynamics, and the evolution of global ecology. Discovering Evolutionary Ecology highlights the connections between these different subject areas, and for the first time paints a picture of a truly integrated field. It illustrates the research tools utilized, and demonstrates how advances in one area can spur on developments elsewhere when scientists combine evolutionary and ecological knowledge. To maximize accessibility, the book assumes only a basic knowledge of biology, includes a comprehensive glossary, and contains almost no maths. Each chapter provides suggestions for further reading, and there is also an extensive reference list. Ideal as an introduction to evolutionary ecology for undergraduates, this book will also interest established researchers, providing a broad and up-to-date context for their work.

In The Adapted Mind, Jerome Barkow, along with Leda Cosmides and John Tooby, set out to redefine evolutionary psychology for the social sciences and to create a new agenda for the next generation of social scientists. While biologically oriented psychologists quickly accepted the work, social scientists in psychology and researchers in anthropology and sociology, who deal with the same questions of human behavior, were more resistant. Missing the Revolution is an invitation to researchers from these disciplines who, in Barkow's view, have been missing the great evolution-revolution of our time to engage with Darwinian thought, which is now so large a part of the non-sociological study of human nature and society. Barkow asks the reader to put aside the preconceptions and stereotypes social scientists often have of the "biological" and to take into account a powerful paradigm that is far away from those past generations who would invoke a vocabulary of "genes" and "Darwin" as justification for genocide. The evolutionary perspective, Barkow maintains, provides no particular support for the status quo, no rationalizations for racism or any other form of social inequality. "Cultural" cannot possibly be opposed to "biological" because culture and society are the only means we have of expressing our evolved psychology; social-cultural constructionism is not only compatible with an evolutionary approach but demanded by it. To marshal evidence for his argument, Barkow has gathered together eminent scholars from a variety of disciplines to present applications of evolutionary psychology in a manner intended to illustrate their relevance to current concerns for social scientists. The contributorsinclude, among others, evolutionary psychologist Anne Campbell, a Darwinian feminist who reaches out to feminist social cosntructionists; sociologist Ulica Segarstrale, who analyzes the opposition of the "cultural left" to Darwinism; sociologist Bernd Baldus, who criticizes evolutionists for ignoring agency; criminologist Anthony Walsh, who presents a biosocial criminology; and primatologists Lars Rodseth and Shannon A. Novak, who reveal an unexpected uniqueness to human social organization. Missing the Revolution is a challenge to scholars to think critically about a powerful social and intellectual movement which insists that the theoretical perspective that has been so successful when applied to the behavior of other animal species can be applied to our own.

The male thynnine wasp's extreme sexual enthusiasm is crucial to reproduction of hammer orchids in the wild. Hammer orchids have co-evolved to produce odors identical to those manufactured by female thynnine wasps. The male wasp's superb sensitivity to the scent of his female mate is the basis for the hammer orchid's deceit--in effect, orchids exploit the male insect's highly adaptive sense of smell for their own propagation. While pollinating orchids is a waste of time, and thus a maladaptive activity for a wasp, his mistake comes about because he must react quickly whenever he senses a possible mate nearby. Alcock suggests that, "for insects, he who hesitates is lost, although perhaps it would be better to say that he who hesitates often loses a chance to pass on his genes."
This book abounds with clever explanations for how these exceptionally complex flowers came to be shaped as they are. The reader can explore many aspects of orchid biology and history ranging from how some species avoid inbreeding, to the origins of orchids from an ancestor that belonged to the asparagus family. Examining each component of an orchid's flower, Alcock explains how the various parts work together to produce the plant's minute offspring. Each element of an orchid, as quirky as it may seem, is biologically significant, bearing the imprint of natural selection. Readers can share in the delight that Darwin and all other orchid enthusiasts have felt in making sense of even the smallest of details of these most wonderful plants.

This book describes the biodiversity and biogeography of nothern Mexico, documents the biological importance of regional ecosystems and the impacts of human land use on the conservation status of plants and wildlife. It should become the standard source document for the conservation status of species and ecosystems in this region, which is of unusual biological interest because of its high biodiversity and highly varied landscape and biological zonation.

This book looks at how an animal is organized to carry out a difficult task - that of feeding on plants. The complex adaptations necessary to enable animals to obtain nutrients successfully from a herbivorous diet are many. What structures are needed in the mouth, for example, or in the digestive system? How is behaviour adapted to allow an animal to survive and reproduce on a diet of plant material? For the first time, these problems are examined here purely from the perspective of the reptiles. Individual groups are looked at the structural, physiological and ecological adaptations of the herbivorous members are reviewed. The groups discussed include the modern reptiles, the lizards and the turtles and also extinct reptiles, the dinosaurs and the mammal-like reptiles. Common themes are teased out and arranged chronologically to help gain an understanding of the patterns of diversity change in the group. This book will be of great interest to researchers and students of zoology, palaeontology, evolution, ecology, functional anatomy and morphology.

Philosophy in Reality offers a new vision of the relation between science and philosophy in the framework of a non-propositional logic of real processes, grounded in the physics of the real world. This logical system is based on the work of the Franco-Romanian thinker Stephane Lupasco (1900-1988), previously presented by Joseph Brenner in the book Logic in Reality (Springer, 2008). The present book was inspired in part by the ancient Chinese Book of Changes (I Ching) and its scientific-philosophical discussion of change. The emphasis in Philosophy in Reality is on the recovery of dialectics and semantics from reductionist applications and their incorporation into a new synthetic paradigm for knowledge. Through an original re-interpretation of both classical and modern Western thought, this book addresses philosophical issues in scientific fields as well as long-standing conceptual problems such as the origin, nature and role of meaning, the unity of knowledge and the origin of morality. In a rigorous transdisciplinary manner, it discusses foundational and current issues in the physical sciences - mathematics, information, communication and systems theory and their implications for philosophy. The same framework is applied to problems of the origins of society, the transformation of reality by human subjects, and the emergence of a global, sustainable information society. In summary, Philosophy in Reality provides a wealth of new perspectives and references, supporting research by both philosophers and physical and social scientists concerned with the many facets of reality.

This book takes a new approach to the debate on causal pluralism in the philosophy of biology by asking how useful pluralism is instead of debating its truth. The core thesis in this work is that many problems do not hinge on the question of whether or not we subscribe to causal pluralism. As one step in this central argument, the author develops an account that reasonably distinguishes pluralism from monism; in another step he studies cases that allegedly motivate causal pluralism in biology. Examining these cases shows how pluralism is often irrelevant and why pursuing pluralism is sometimes dangerous, since it may generate pseudo solutions to persistent philosophical problems. This book offers a systematic approach to this subject matter and argues that we might have overestimated the significance of the monism-pluralism distinction and at the same time failed to see the risks of pursuing causal pluralism.

Using an interdisciplinary approach, the authors provide an adaptionist interpretation of the basic features of recombination, its evolutionary significance as a key process in reproduction and its importance in genetic mapping. The book synthesizes much recent information in the fields of evloutionary genetics of recombination, the analysis of genetic markers and breeding applications. The authors analyse recombination through a consideration of computer models, large Drosophila populations and an empirical approach to current theories. Practically-orientated readers will be interested in the discussion of a wide spectrum of mapping methods and the new algorithms proposed for genetic mapping of quantitative loci.

This second edition integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular, cellular and evolutionary biology. This broad, unified approach is made possible, in large part, by the very wide scope of Dr. Xia's own research experience. The integration of genomics, proteomics and transcriptomics into a single volume makes this book required reading for anyone entering the new and emerging fields of Systems Biology and Evolutionary Bioinformatics.