Uber die Tatsache, dass bei plotzlichen Todesfallen Kohlenmonoxyd-Hamo- globinwerte unterschiedlicher Hohe und unterschiedlichen Beweiswertes im Hinblick auf die Todesursache festgestellt werden konnen, ist oft berichtet worden (Bode u. Kampmann 1982; Geldmacher-v.Mallinckrodt 1975; Mueller 1953; Pollak 1978). Die Bedeutung dieser fruher haufigsten Ver- giftungsart ist inzwischen gegenuber anderen Intoxikationen zuruckge- gangen (Schwerd 1979). Im Hinblick auf die Zunahme von Kombinationsver- giftungen war uns wie anderen (Bode u. Kampmann 1982) in den letzten Jahren eine Zunahme der Falle mit niedrigen Kohlenmonoxyd-Hamoglobin- konzentrationen aufgefallen, deren Ursachen nicht unbedingt auf der Hand lagen. Wir wollten wissen, welche Bedeutung der Feststellung eines bestimmten CO-Hb-Wertes bei einem plotzlichen Todesfall heutzutage kommt. Material und Methoden Wir haben alle Falle des Institutes der vergangenen zwanzig Jahre, in denen eine Bestimmung des Gehaltes an Kohlenmonoxyd-Hamoglobin nach Heilmeyer (1933) mit der Zweilangenmethode bei 560 und 575 nm, modi- fiziert nach Schwerd (1962), wie von einem von uns beschrieben (Sellier 1953), vorgenommen worden war, aufgeschlusselt. 45 Falle mit einem Wert von 0% wurden von vornherein ausgeschieden, weil es sich offenbar um Routinekontrollen bei anderer gesicherter Todesursache gehandelt hatte. In 17 Fallen war die Feststellung von 0% CO-Hb von forensischer Bedeu- tung. Ausgehend von einer Gefahrdungsgrenze von = 50% CO-HB (Mueller 1953; Prokop u. Gohler 1976; Schwerd 1979) wurden in den Jahren 1963 bis 1982 insgesamt 26 Falle mit Werten zwischen 0 und ~ 50% analysiert.

Francois Delaporte's Chagas Disease chronicles Brazilian medicine's encounter with a disease, an insect, and a history of discovery. Between 1909 and 1911, Carlos Chagas described an infection (pathogenic trypanosome), its intermediate host, and the illness that he believed it caused, parasitic thyroiditis. Chagas's work did not lack significance: the disease that came to share his name would be one of Latin America's most serious endemic diseases. However, the clinical identification of the disease through "Romana's sign" (a palpebral edema or swelling of the eyelid) some decades later marked a transformation in the general medical knowledge of the disease and its basis altogether. Not only was the disease entity that Chagas had described shown to be a nosological illusion, but twenty-five years of scientific controversy turned out to have been based on a misunderstanding. The continued use of the term "Chagas's Disease" even after Cecilio Romana's discovery thus refers to a fundamental ambiguity. Delaporte dispels this ambiguity by re-examining the various discoveries, dead ends, controversies, and major epistemological transformations that marked the history of the disease--a history that begins with the creation of the Oswaldo Cruz Institute in Rio de Janeiro and ends in the forests of Santa Fe in northern Argentina. Delaporte's study shows how an epistemological focus can add depth to the history of medicine and complexity to accounts of scientific discovery.

This book provides, in a single volume, an extensive, research-based evaluation of the most popular clinical assessment tools as applied in forensic settings. These widely used instruments often require important modifications in their administration and interpretation when used for forensic purposes, and it is vital that the clinician is intimately familiar with their correct application, as well as their limitations. The test instruments included are analyzed by senior figures in the field of psychological assessment who are uniquely qualified to discuss them because they have either had a crucial role in the development of the tests, or they have dedicated their careers to advancing our understanding of these clinical assessment measures. Each chapter begins with a summary of the development of the assessment instrument in its more traditional applications in clinical settings, and then considers its utilization in forensic settings. The types of forensic issues which have been addressed with that instrument are reviewed, and an illustrative case example is given which reflects the types of uses and limitations of the assessment technique when applied in a forensic context. New in this edition are a chapter on the MMPI-2-RF and separate chapters for the adult and youth versions of the Hare Psychopathy Checklist. Psychologists using assessment instruments in applied forensic settings will find this to be a valuable and practical source of information, as will attorneys wishing to gain an understanding of the application of these psychological assessment approaches in the courtroom.

Essentials of Autopsy Practice is dedicated to updating the modern pathologist on the issues related to the autopsy. This first volume contains 12 topical chapters which are not covered in any other text. It comprises the most recent developments in current autopsy and relevant subjects that have not yet been covered in current autopsy textbooks. This is what makes this book exceptional in its field. The book will be of interest to both trainees and consultants in all sub-branches of pathology including forensic pathology. The subject matter will also appeal to other areas of clinical medicine and will make a good reference book.

Margaret Stark and a team of authoritative experts offer a timely survey of the fundamental principles and latest developments in clinical forensic medicine. Topics range from sexual assault examination to injury interpretation, from nonaccidental injury in children, to crowd control agents. Also included are extensive discussions of the care of detainees, the management of substance abuse detainees in custody, the causes and prevention of deaths in custody, and the fundamentals of traffic medicine. In the absence of international standards of training, the authors also address the basic issues of consent, confidentiality, note-keeping, court reporting, and attendance in court. Comprehensive and authoritative, A Physicians Guide to Clinical Forensic Medicine offers forensic specialists and allied professionals a reliable, up-to-date guide to proven practices and procedures for a every variety of police inquiry requiring clinical forensic investigation.

One of the surprising things about the natural world is that animals are dying around us all the time and yet we rarely see any evidence of it. This is a testimony to the efficiency of the large variety of organisms which decompose animal corpses. Whilst bacteria and fungi are the main groups involved in decomposition processes, the larger insects additionally provide an important physical disruption of body tissues, which aids the penetration of micro organisms and speeds the collapse of the body structure. A human corpse is treated no differently and the same groups of organisms are involved. From a forensic science viewpoint the universality of the decay process provides two major advantages. Information based on the decomposition of animals is of considerable value when considering human cases and the successional pattern of decay is broadly equivalent wherever the process is being studied. Historically, the usefulness of insects in solving crime can be traced back in the literature to the 13th century. McKnight 1, 2] translated a Chinese text of this period which contains an account of how a law officer dealt with a case of murder in the rice fields. Death had been caused by a sickle and the official ordered all the field workers to line up and lay their sickles on the ground in front of them. Flies began to be attracted to one of the sickles whereupon its owner confessed to the crime."

This book provides, in a single volume, an extensive, research-based evaluation of the most popular clinical assessment tools as applied in forensic settings. These widely used instruments often require important modifications in their administration and interpretation when used for forensic purposes, and it is vital that the clinician is intimately familiar with their correct application, as well as their limitations. The test instruments included are analyzed by senior figures in the field of psychological assessment who are uniquely qualified to discuss them because they have either had a crucial role in the development of the tests, or they have dedicated their careers to advancing our understanding of these clinical assessment measures. Each chapter begins with a summary of the development of the assessment instrument in its more traditional applications in clinical settings, and then considers its utilization in forensic settings. The types of forensic issues which have been addressed with that instrument are reviewed, and an illustrative case example is given which reflects the types of uses and limitations of the assessment technique when applied in a forensic context. New in this edition are a chapter on the MMPI-2-RF and separate chapters for the adult and youth versions of the Hare Psychopathy Checklist. Psychologists using assessment instruments in applied forensic settings will find this to be a valuable and practical source of information, as will attorneys wishing to gain an understanding of the application of these psychological assessment approaches in the courtroom.

"Forensic Medicine," written by L. Buris, Professor of Forensic Medicine at the Debrecen Medical University in Hungary, is an informative and practice-oriented review of the topic. The book contains essential data and references of forensic medicine, both in theoretical and practical aspects. It gives a pathological, pathophysiological and biochemical interpretation of various alterations with the up-to-date results of forensic medical research as well.

Imaging for Forensics and Security: From Theory to Practice provides a detailed analysis of new imaging and pattern recognition techniques for the understanding and deployment of biometrics and forensic techniques as practical solutions to increase security. It contains a collection of the recent advances in the technology ranging from theory, design, and implementation to performance evaluation of biometric and forensic systems. This book also contains new methods such as the multiscale approach, directional filter bank, and wavelet maxima for the development of practical solutions to biometric problems.

The book introduces a new forensic system based on shoeprint imagery with advanced techniques for use in forensics applications. It also presents the concept of protecting the originality of biometric images stored in databases against intentional and unintentional attacks and fraud detection data in order to further increase the security.

Fresh research has opened up new vistas in forensic pathology that are allowing for closer national and international cooperation between pathologists and scientists in a range of medical and scientific disciplines. At the same time, autopsy and laboratory techniques are undergoing rapid evolution, with new procedures coming on stream while existing processes yield additional -- and more accurate -- results. This sixth volume of reviews in forensic pathology provides professionals working in the field with cutting-edge material on the latest key advances in the fields of traumatic death, sudden natural death and death time estimation. Now with numerous color illustrations, the book gives forensic experts across the world a fully up-to-date guide to contemporary procedures and theory in forensic science and medicine. The chapters cover an exhaustive range of aspects in the discipline, from the analysis of sudden natural deaths in infancy and childhood to the cardiac proteomics approach in the study of cases involving sudden cardiac death. Other specialist chapters deal with the forensic investigation of deaths in aviation and as a result of accidents involving all- terrain vehicles. The volume covers fresh research in the use of protein markers for the estimation of post-mortem intervals, and features a chapter telling the story of the medico-legal investigation into the deaths resulting from the 9-11 terrorist attacks on the World Trade Center.Comprehensive and current, this fresh volume of reviews is an essential resource for professionals who need to stay ahead of the game in a fast-moving and exciting field of scientific endeavor.

To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park 1828]). Closely linked with the great therapeutic importance of the benzodia zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment of epileptic conditions ("drug monitoring"), but also in connection with questions at issue in toxicology and traffic medicine. A toxicological analysis can be subdivided into the following steps: Detection (identification including screening) Determination (e. g. blood, plasma or serum levels) Interpretation of the analytical results. This book is intended as a contribution to each of these chapters: The part "Analytical Data" (pp.I-122) gives a comprehensive collec tion of data, e.g. general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo phenone derivatives is also given. The most important analytical methods are presented in an extensive review on pp.123-204 in order to make it possible to select the optimum method on the basis of the essential data."

Alcohol abuse, alcohol intolerance, alcohol dependence and other alcohol-related disabilities are some of the most challenging public health problems facing our modern-day society. The purpose of this comprehensive monograph is to review the available knowledge concerning the pharmacogenetic basis of alcohol sensitivity and its physiolgical implications and to synthesize the bulk of existing knowledge regarding metabolic features and biomedical disturbances related to alcoholism. The chapters cover a broad array of disciplines including an overview of historical and epidemiological aspects, biochemistry and molecular genetics of enzymes involved in alcohol metabolism, biochemical and neuropsychopharmacological effects of alcohol. Major emphasis is placed on the role of genetic factors in alcoholism. The experimental details are summarized and a comprehensive bibliography is included.

Essentials of Autopsy Practice updates the modern pathologist on issues related to the autopsy. This volume contains topical chapters on the pathology of shock, religious attitudes to death, incised wounds, radiological investigations, metabolic disorders in childhood, maternal deaths, body alterations and piercings which are comprehensive, unique and educational. It brings the literature together into a modern, up-to-date review of the subject, each authored by experts in their field. It comprises the most recent developments in current autopsy practice making the book unique and exceptional - a valuable aid for the bench top, autopsy suite, laboratory or library. A hands-on reference book, Essentials of Autopsy Practice is of interest to both trainees and consultants in all sub-branches of pathology including forensic pathology. It can also be used by non-medical staff involved in the dead, such as nurses, police, lawyers and bereavement officers.

Ancient DNA Typing is a comprehensive manual about the analysis of ancient and degraded DNA. It is an equally useful textbook and working tool for various disciplines such as: Anthropology, Archaeology, Forensic Medicine, Conservation Biology, Environmental Sciences and Food Engineering.
The reader benefits from a clear division of strategies, methods and applications with many interesting examples of the analysis of historic skeletal and cultural remains. The book contains a detailed protocol chapter which serves as a lab manual with the most important methods for DNA extraction, PCR and electrophoretic analysis of degraded samples. The appendix helps to set up a PCR lab specializing in ancient DNA research and answers the most frequent questions concerning technical problems in investigations of degraded DNA.

In this new volume of the globally recognized Forensic Pathology Reviews, Dr. Michael Tsokos has gathered chapters from the top experts in the field to reveal both the applied and scientific areas of expertise along the broad spectrum of forensics studies. Volume 5 piques the mind as leading forensic pathologists from the United States and around the world offer advanced insight into death caused environmental conditions, trauma, neuropathology, natural causes, and ballistics. The authors of this volume further their exploration as they impart research related to identification, serial murder, histopathology, and age estimation. While unveiling unsurpassed and cutting-edge knowledge, Forensic Pathology Reviews, Volume 5 will also inspire emerging forensic scientists to immerse themselves in innovative research.

Herbal Products: Toxicology and Clinical Pharmacology, Second Edition builds on the informative foundation laid by its predecessor. This fully revised and expanded second edition boasts more than 200 new references that document efficacy studies and adverse effects and four new chapters devoted to dietary products. Practitioners and researchers will find that this volume is a comprehensive resource for objective clinical information.

Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Recent political, religious, ethnic, and racial conflicts, as well as mass disasters, have significantly helped to bring to light the almost unknown dis- pline of forensic anthropology. This science has become particularly useful to forensic pathologists because it aids in solving various puzzles, such as id- tifying victims and documenting crimes. On topics such as mass disasters and crimes against humanity, teamwork between forensic pathologists and for- sic anthropologists has significantly increased over the few last years. This relationship has also improved the study of routine cases in local medicolegal institutes. When human remains are badly decomposed, partially skelet- ized, and/or burned, it is particularly useful for the forensic pathologist to be assisted by a forensic anthropologist. It is not a one-way situation: when the forensic anthropologist deals with skeletonized bodies that have some kind of soft tissue, the advice of a forensic pathologist would be welcome. Forensic anthropology is a subspecialty/field of physical anthropology. Most of the background on skeletal biology was gathered on the basis of sk- etal remains from past populations. Physical anthropologists then developed an indisputable "know-how"; nevertheless, one must keep in mind that looking for a missing person or checking an assumed identity is quite a different matter. Pieces of information needed by forensic anthropologists require a higher level of reliability and accuracy than those granted in a general archaeological c- text. To achieve a positive identification, findings have to match with e- dence, particularly when genetic identification is not possible.

This reference book provides an update on the advances and developments in autopsy practice. The book is designed to be kept in laboratories, offices and mortuaries so that pathologists can quickly reach for it and look up how to undertake procedures or interpret findings found in autopsy practice. Useful to both trainees and consultants in all specialty areas within pathology, the book also serves as a guide to all those involved in death investigation.

Crib death (SIDS) is the most frequent cause of death for infants during the first year. A systematic study of the autonomic nervous system and cardiac system has been performed on a large number of infants and fetuses who died suddenly and unexpectedly, as well as in age-matched control cases. The neurological and cardiac findings are described here, and the relationship between SIDS and unexplained fetal death is discussed.

Guidelines for Reports by Autopsy Pathologists is intended to help the autopsy pathologist produce reports that communicate well. Having evolved from a coll- tion of faculty critiques of the autopsy reports, summary and opinion reports, scene reports, and death certi?cates produced by residents in anatomic pathology and f- lows in forensic pathology, the book emphasizes topics that have been troublesome for trainees. For clinicians, the medical record describes their work product. For autopsy pathologists, the written report is the work product and demands an acco- ingly higher standard of composition. Most reports produced by pathologists can be divided into objective and subjective elements, or, in other words, ?ndings and opinions. The pathologist must have a clear understanding of the linkage between the two. When composing a report, the autopsy pathologist should serve the goal of c- municating to the parties who will read the report, namely, the case pathologist him- or herself (at a later date), attorneys, the family of the decedent, and other physicians. I believe that careless and imprecise thinking leads to sloppy language, and that sloppy language leads to careless and imprecise thinking. In my experience, pathologists who learn how to clearly express and organize their ?ndings and op- ions in a written format make more detailed and focused observations at the autopsy table.

This second edition, completely revised and expanded with a new chapter on lower extremity trauma, presents chapters written by widely recognized authorities in the field of human traumatic injury. The topics covered range from automobile restraint systems to cell and tissue biomechanics, and will interest a variety of scholars and professionals including physicians; biomechanical researchers; mechanical, biomedical and automotive engineers; as well as attorneys and jurists involved in accidental injury cases.

A city with eight million people has eight million ways to die For fifteen years, Shiya Ribowsky worked as a medicolegal investigator in New York City's medical examiner's office--the largest, most sophisticated organization of its kind in the world. Utilizing his background in medicine, he led the investigations of more than eight thousand individual deaths, becoming a key figure in some of New York's most bizarre death cases and eventually taking charge of the largest forensic investigation ever attempted: identifying the dead in the aftermath of the September 11 tragedies. Now, in this mesmerizing book, Ribowsky pulls back the curtain on the New York City's medical examiner's office, giving an enthralling, never-before-seen glimpse into death and the city. Born and raised in New York City's orthodox Jewish community, Ribowsky seems an unlikely candidate for this macabre profession. Nevertheless he has forsaken a promising career of medical work with the living, descending instead into the realm of the dead, enticed by the challenge of confronting death on a daily basis. Taking you through the vermin-infested Bowery flophouses and posh Upper East Side apartments of the city's dead, Ribowsky explores in gruesome detail the skeletons that hang in the Big Apple's closets. Combing through the autopsy room, he also exposes the grim secrets that only a scalpel and a dead body can tell and explains how forensic investigation does not merely solve crimes--it saves lives. But it is in the aftermath of September 11 that the ME's office is handed its biggest challenge: to identify as many of the fallen as possible. With poignant descriptions, Ribowsky provides a dramatic account of the office's diligent and unflappable work with the families of the victims, helping them emerge from the ashes of this tragedy while displaying the strength, grit, intelligence, and compassion that Americans expect from true New Yorkers. At once compelling and heartbreaking, Dead Center is a story of New York unlike any other, blending the haunting with the sublime, while painting a striking portrait of death (and life) in the city that never sleeps.

A practical hands-on bench book covering difficult areas of autopsy for the modern pathologist. Rutty's book is unique - chapters deal with issues never previously discussed and have been specifically selected to fill a gap in the market, not just re-hash old ideas.

Designed for consultants and trainees alike, not only pathologists of all types but also non-medics involved with the dead in any way - lawyers, police, bereavement officers, undertakers. The first volume has become a reference aid to autopsy issues for all grades of lawyers. Thus the audience that the book reaches is greater than a pure autopsy or forensic pathology textbook.

This volume presents an overview of computer forensics perfect for beginners. A distinguished group of specialist authors have crafted chapters rich with detail yet accessible for readers who are not experts in the field. Tying together topics as diverse as applicable laws on search and seizure, investigating cybercrime, and preparation for courtroom testimony, Handbook of Digital and Multimedia Evidence is an ideal overall reference for this multi-faceted discipline.