This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the "Bio-Medicolegal Sciences", historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book's conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.

Post-mortem computed tomography (PMCT) is increasingly used in forensic pathology practice in many jurisdictions. Such imaging has expanded the capacity to evaluate skeletal trauma improving the visualisation, documentation and presentation of forensic findings. Typically when deceased persons are located and exhibit evidence of trauma, forensic pathologist, anthropologists and radiologists base their interpretations of the mechanism of trauma on their experience and understanding of the biomechanics of fractures as well as recognisable patterns of injury. In order to augment this process, An Atlas of Forensic Skeletal Trauma presents a range of de-identified adult and child skeletal trauma cases that occur in medico-legal contexts where the cause of death and mechanism of trauma are recorded. An Atlas of Forensic Skeletal Trauma includes comprehensive photographs and PMCT images as well as descriptive text.

This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.

Osteoarchaeology: A Guide to the Macroscopic Study of Human Skeletal Remains covers the identification of bones and teeth, taphonomy, sex, ancestry assessment, age estimation, the analysis of biodistances, growth patterns and activity markers, and paleopathology. The book aims to familiarize the reader with the main applications of osteoarchaeology and provide the necessary knowledge required for the implementation of a broad range of osteological methods. It is ideal as a complement to existing textbooks used in upper level undergraduate and graduate courses on osteoarchaeology, human osteology, and, to some extent, forensic anthropology. Pedagogical features include ample illustrations, case study material, revision exercises, and a glossary. Additional features comprise macros that facilitate data processing and analysis, as well as an extensive chapter on applied statistics.

Causation and Risk in the Law of Torts provides a comparative account of the legal and scientific issues relating to proof of causation in cases of alleged drug-induced injury, principally in Europe and North America.

This text seeks to assess whether, by using probabilistic approaches, the courts may more accurately determine the cause of adverse reactions contentiously associated with drugs. In four case studies (DES, Bondoctin, vaccine damage and "Gulf War Syndrome"), the deficiencies of orthodox approaches to causation are revealed. A sustained argument is presented in favor of applying greater weight to epidemiological statistics, as refined by the application of the Bayes' Theorem.

A valuable feature of this book is the discussion of the role of expert witnesses, including an examination of how the author's proposals could be accommodated with the reformed civil process envisaged by the Woolf Report.

Goldberg also examines the economic implications of these proposals. Causation and Risk in the Law of Torts is a timely contribution to the resolution of the legal problems in this complex area of tort law.

Forensic Pathology, the latest volume in the Advanced Forensic Science series that grew out of the recommendations from the 2009 NAS Report serves as a graduate level text for those studying and teaching forensic pathology, and is an excellent reference for forensic pathologists' libraries or for use in their casework. Coverage includes postmortem interval, autopsy, trauma, causes of death, identification, and professional issues. Edited by a world-renowned leading forensic expert, this series provides a long overdue solution for the forensic science community.

This book challenges the assumptions of modern criminal law that insanity is a natural, legally and medically defined phenomenon (covering a range of medical disorders). By doing so, it paves the way for a new perspective on insanity and can serve as the basis for a new approach to insanity in modern criminal law. The book covers the following aspects: the structure of the principle of fault in modern criminal law, the development of the insanity defense in criminal law, tangential in personam defenses in criminal law and their implications for insanity and the legal mechanism of reproduction of fault. The focus is on the Anglo-American and European-Continental legal systems. Given the attention consistently drawn by international and domestic events in this context, the book will be of interest to a broad and growing international audience.

The Analysis of Burned Human Remains, Second Edition, provides a primary source for osteologists and the medical/legal community for the understanding of burned bone remains in forensic or archaeological contexts. It describes in detail the changes in human bone and soft tissues as a body burns at both the chemical and gross levels and provides an overview of the current procedures in burned bone study. Case studies in forensic and archaeological settings aid those interested in the analysis of burned human bodies, from death scene investigators to biological anthropologists.

Dr. Robert Sadoff's The Evolution of Forensic Psychiatry is extraordinarily unique in that it is not intended to be a textbook or a guide to forensic psychiatry. Instead, this book is a fascinating mix of historical beginnings, current developments, representative subspecialties of psychiatry, and several allied disciplines and their impact on forensic psychiatry. Furthermore, it also includes neuroscientific research and how it translates to civic and criminal case work. Judges, attorneys, law professors and a police scientist all weigh in on the influence of the interdisciplinary research these forensic scientists have had on the justice system. Featuring case examples and research conducted by the professionals who have had the greatest influence on the growth of the field of forensic psychiatry, they lead the discussion on the various aspects and issues of the discipline's impact on the criminal justice system.

The relationship of scientific research on human sexuality (sexology) to society's legal, judicial, and law enforcement systems (forensics) is the focus of this encyclopaedic volume. Editors James J. Krivacska and John Money have assembled contributions by leading experts, covering a wide range of legal and medical issues pertaining to the interconnection between law and sexual behaviour. Section one examines the nature of paraphilic behaviour and the social framework within which some of it becomes illegal. The topics discussed include sodomy, paedophilia, incest, sexual abuse, rape, exhibitionism, prostitution, and sexual harassment. Section two looks at current strategies for assessing the problems of sex offenders and victims. Among the areas addressed are 'real' sexual abuse vs. 'manufactured' allegations of abuse memories, allegations of satanism and ritual sexual abuse, and the difficulties of treating sex offenders within a legal framework. The final section argues that sexology has much to contribute to the debate of the appropriate role of government in regulating the private sexual behaviour of the citizenry. Sex education, contraception, abortion, AIDS, pornography, social tolerance vs. criminalisation, and a comparative view of public sex policy in China and Russia are among the subjects reviewed.

When a loved one dies in a mysterious manner, we rely on coroners and medical examiners to tell us what happened. The stakes are high: Coroners seek justice for the dead, exoneration for the wrongfully accused, and closure for the families of victims. They are always on call and work closely with law enforcement.

Author Robert S. West, who served as a physician-coroner in rural Kootenai County, Idaho, from 1970 to 2011, delves into the challenges he faced on the job. While he often lacked resources, he always did the best he could to serve his community, solving numerous mysteries using the tactics of forensic medicine.

Dr. West also explores the shortcomings of the coroner/medical examiner system and how it can be improved. Widely varying educational requirements and unrealistic expectations need to be balanced in order to fill the shortage of forensic pathologists while enhancing the training of current coroners.

Join a coroner from rural northern Idaho as he looks back at his career's most challenging cases and explains how to reform the system in It Can (and Does) Happen Here

This book presents recent applications and approaches as well as challenges in digital forensic science. One of the evolving challenges that is covered in the book is the cloud forensic analysis which applies the digital forensic science over the cloud computing paradigm for conducting either live or static investigations within the cloud environment. The book also covers the theme of multimedia forensics and watermarking in the area of information security. That includes highlights on intelligence techniques designed for detecting significant changes in image and video sequences. Moreover, the theme proposes recent robust and computationally efficient digital watermarking techniques. The last part of the book provides several digital forensics related applications, including areas such as evidence acquisition enhancement, evidence evaluation, cryptography, and finally, live investigation through the importance of reconstructing the botnet attack scenario to show the malicious activities and files as evidences to be presented in a court.

This subject, written for psychiatrists, is of importance and relevance to psychiatrists dealing with apsects of the practice that cross with legal professionals and with school and corporate professionals. This subject of Forensic Psychiatry presents topics on: Psychopharmacologic treatment of aggression; Assessment of blackouts and claimed amnesia; Forensic assessment of bullying; Testamentary capacity and guardianship assessments; Psychological testing and the assessment of malingering; Child murder by parents; Mass murderers: who are they and how might we stop them?; Child pornography and the Internet; Do's and don'ts of depositions; Juvenile offenders: Updates on competency and culpability; The role of the forensic psychiatrist in the immigration process; and Psychiatric Management of the Problematic Employee. The topics are presented to include coverage of Nature and Definition of the Problem, Physical Examination, Evaluation, Competency Evaluation, Clinical Assessment Strategies, Psychiatric Testing Strategies, Reaching an Opinion, with Key Points of every topic.

Computational Intelligence techniques have been widely explored in various domains including forensics. Analysis in forensic encompasses the study of pattern analysis that answer the question of interest in security, medical, legal, genetic studies and etc. However, forensic analysis is usually performed through experiments in lab which is expensive both in cost and time. Therefore, this book seeks to explore the progress and advancement of computational intelligence technique in different focus areas of forensic studies. This aims to build stronger connection between computer scientists and forensic field experts.

This book, "Computational Intelligence in" "Digital Forensics: Forensic Investigation and Applications," is the first volume in the Intelligent Systems Reference Library series. The book presents original research results and innovative applications of computational intelligence in digital forensics. This edited volume contains seventeen chapters and presents the latest state-of-the-art advancement of Computational Intelligence in Digital Forensics; in both theoretical and application papers related to novel discovery in intelligent forensics. The chapters are further organized into three sections: (1) Introduction, (2) Forensic Discovery and Investigation, which discusses the computational intelligence technologies employed in Digital Forensic, and (3) Intelligent Forensic Science Applications, which encompasses the applications of computational intelligence in Digital Forensic, such as human anthropology, human biometrics, human by products, drugs, and electronic devices.

This volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer. It will coherently review the pathophysiological aspects of the mucin glycoproteins in malignancies and provide an updated account of the status of bromelain and N-acetylcysteine in cancer therapy. The volume will develop the idea of using these two drugs as a combination formulation for mucin-depleting effects.

A broad understanding of bone and tooth microstructure is necessary for constructing the biological profile of an individual or individuals within a population. Bone Histology: An Anthropological Perspective brings together authors with extensive experience and expertise in various aspects of hard tissue histology to provide a comprehensive discussion of the application of methods, current theories, and future directions in hard tissue research related to anthropological questions.

Topics discussed include:

• The biology underlying skeletal growth and development leading to adult skeletal morphology
• Current research in understanding in bone modeling
• Histological features of dental hard tissues and their utility in biological anthropology
• Histological analysis as a means to differentiate human from nonhuman bone and for the purpose of age estimation
• The biomechanics of cortical bone
• Histotaphonomy and how postmortem microstructural change can be used for taphonomic inquiry
• The application of light microscopy in paleopathology to classify pathological conditions
• The histological study of bone tissue of archaeological origin
• Researchers' access to collections of bone samples with known demographic information
• Technological aspects of hard tissue histology, including laboratory requirements and high-resolution imaging

In most cases, the physical remains of humans available to bioarchaeologists, paleopathologists, and paleontologists are limited to skeletal material. Fortunately, these hard tissues are a storehouse of information about biological processes experienced during the life of an individual. This volume provides an overview of the current state of research and potential applications in anthropology and other fields that employ a histological approach to the study of hard tissues.

Geriatric Forensic Psychiatry: Principles and Practice is one of the first texts to provide a comprehensive review of important topics in the intersection of geriatric psychiatry, medicine, clinical neuroscience, forensic psychiatry, and law. It will speak to a broad audience among varied fields, including clinical and forensic psychiatry and mental health professionals, geriatricians and internists, attorneys and courts, regulators, and other professionals working with the older population. Topics addressed in this text, applied to the geriatric population, include clinical forensic evaluation, regulations and laws, civil commitment, different forms of capacity, guardianship, patient rights, medical-legal issues related to treatment, long term care and telemedicine, risk management, patient safety and error reduction, elder driving, sociopathy and aggression, offenders and the adjudication process, criminal evaluations, corrections, ethics, culture, cognitive impairment, substance abuse, trauma, older professionals, high risk behavior, and forensic mental health training and research. Understanding the relationship between clinical issues, laws and regulations, and managing risk and improving safety, will help to serve the growing older population.

Written and edited by the most respected authorities in forensic nursing and forensic sciences, this new edition provides the tools and concepts you need to collect evidence that is admissible in court, determine the significance of that evidence, and provide accurate, reliable testimony while administering high-quality patient care. Now in full color throughout, it remains the most comprehensive, highly illustrated text of its kind. Provides a comprehensive, updated guide to forensic nursing science, paying special attention to the International Association of Forensic Nurses's (IAFN) goals for forensic nursing. Retains a focus on assessment skills and the collection and preservation of evidence, following the established guidelines of the forensic sciences. Prepares you to provide testimony as a fact witness or a forensic nursing expert. Includes an illustrated case study in almost every chapter, helping you relate the information to clinical practice. Highlights important recommendations for interventions in Best Practice boxes, including the evidence base for each. Summarizes important points in Key Point boxes, so you can quickly review the most important concepts in each chapter. Explores the evolving role of forensic nurses in today's health care facilities and the community. Edited by Virginia Lynch, founding member and first President of the International Association of Forensic Nurses and Janet Barber Duval, both well-respected pioneers and educators in the field. Contains 300 full-color illustrations integrated throughout the text, so you can view evidence quickly and easily, as it is likely to appear in practice. Presents information on courtroom testimony and depositions in one reorganized, streamlined chapter, giving you a full, organized treatment of this extremely important topic. Includes twelve new chapters: Digital Evidence, Medical Evidence Recovery at the Death Scene, Asphyxia, Electrical and Thermal Injury, Intrafamilial Homicide and Unexplained Childhood Death, Human Trafficking, Credential Development for Forensic Nurses, Gangs and Hate Crimes, Ethics Issues in Forensic Nursing, Forensic Physics and Fracture Analysis, Sexual Deviant Behaviors and Crime and Forensic Epidemiology. Contains heavily revised information on Prehospital Evidence, Forensic Investigation in the Hospital, and Human Abuse and Deaths in Custody. Features critical thinking questions with every case study, so you can thoroughly consider the implications of each clinical scenario. Evolve site will include appendices and additional documentation materials.

The need for a laboratory and field manual to assist with the evaluation of juvenile skeletal material is long overdue. This resource is essential for the practising osteoarchaeologist and forensic anthropologist who requires a quick, reliable and easy-to-use reference to aid in the identification, siding and aging of juvenile osseous material. While excellent reference books on juvenile osteology are currently available, no pre-existing source adequately fills this particular niche in the market.
This field manual is designed with practicality as its primary directive. Descriptions of each bone contain 1) morphological characteristics useful for identification, 2) other elements with which the bone may be confused, 2) tips for siding, 3) illustrations of varying developmental phases, 4) data useful for ageing, and 5) a summary of developmental timings. Concise, bullet-style descriptions assist with quick retrieval of information.
Unique to this manual is the presentation of data collected from a variety of populations, utilizing a range of observational methods, as an alternative to providing one overall aging summary that is derived from a compilation of many individual sources. This manual provides a host of data on a variety of populations to enable the user to select the reference most applicable to their needs.
The final chapter combines information from each bone to provide a summary of developmental changes occurring at different life stages to act as an immediate 'ready reckoner' for the knowledgeable practitioner. It also provides forms useful for documenting juvenile material and diagrams to help with the recognition of commingled juvenile remains.
The manual is a must for anyone responsible for the evaluation of juvenile osseous material through dry bone assessment, radiographs, sonograms, and or CT scans.
*Identifies every component of the developing skeleton
*Provides detailed analysis of juvenile skeletal remains and the development of bone as a tissue
*Summarizes key morphological stages in the development of every bone
*Provides data on a variety of populations to enable the user to select the reference most applicable to their needs
*Focuses on practicality, with direct, bullet style descriptions
*Provides forms for documenting juvenile material
*Provides diagrams to help with the recognition of commingled juvenile remains
*Final chapter provides summary of developmental changes occurring at different life stages to act as an immediate 'ready reckoner' for the practitioner