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Books > Medicine > General issues > General
Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed,
Published, Cited provides a full methodological and statistical
overview for researchers, clinicians, students, and post-doctoral
fellows conducting genetic and genomic research. Here, active
geneticists, clinicians, and bioinformaticists offer practical
solutions for a variety of challenges associated with several
modern approaches in genetics and genomics, including genotyping,
gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic
sequencing, and gene editing. Emphasis is placed on rigor and
reproducibility throughout, with each section containing laboratory
case-studies and classroom activities covering step-by-step
protocols, best practices, and common pitfalls. Specific genetic
and genomic technologies discussed include microarray analysis,
DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and
CRISPR-based genetic analysis. Training exercises, supporting data,
and in-depth discussions of rigor, reproducibility, and ethics in
research together deliver a solid foundation in research standards
for the next generation of genetic and genomic scientists.
When a medical whistleblower goes missing, private investigator
Charlie Cameron agrees to take on the case.Gavin Law exposed a
tragic case of medical malpractice but now he's missing. It's just
another case for Glasgow PI, Charlie Cameron, until he comes to
believe Law was murdered. Did the disgraced surgeon abandon his
sacred oath to become a killer? Or did the hospital itself have Law
permanently silenced? As Charlie digs deeper, he discovers just how
bad the world of medicine could be for his health. Across the city,
gangster Sean Rafferty is preparing to exploit the corrupt city
council through a multi-million-pound leisure development known as
Riverside. The project will be good for Glasgow. But not everybody
is keen to work with Rafferty. With more than money at stake, Sean
will do anything to get his way. So, when Charlie's investigation
gets tangled up with Sean's business, someone's going to need a
doctor...or an undertaker. Owen Mullen is a best-selling author of
psychological and gangland thrillers. His fast-paced, twist-aplenty
stories are perfect for all fans of Robert Galbraith, Ian Rankin
and Ann Cleeves. This book was previously published as Before The
Devil Knows Your Dead. What readers say about Owen Mullen: 'Owen
Mullen knows how to ramp up the action just when it's needed... he
never fails to give you hard-hitting thrillers that have moments
that will stay with you forever...' 'One of the very best thriller
writers I have ever read.' 'Owen Mullen writes a good story, he
really brings his characters to life and the endings are hard to
guess and never what you expected.'
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