This very important work laid the foundation for my subsequent dissertation and for my research work and publications on colorectal cancer. For the first time, several authors systematically summarized one disease exclusively as to its origins, pathology, diagnostics and therapy. This novel concept made a lasting impression on me in my scientific work. Manfred Georg Krukemeyer, MD, Department of Surgical Research, Westphalian Wilhelm University, Munster"

This monograph is a summary of observations collected over the past ten years on vagal denervation of the stomach and the functional pathology of the vagotomized stomach. It is primarily a continuation of the work we (Holle and Heinrich, 1954) began with fundectomy - the prototype of proximal dener vation of the stomach. This was the starting point for the develop ment of selective proximal vagotomy (SPV). Between 1961 and 1964 the SPY technique was developed to the extent that it could be applied clinically from January 1,1964. Like most clinical innovations, the development took place in several stages. A report on the first 235 surgical cases (1961-1967) appeared in 1968 in F. Holle's Special Surgery of the Stomach, pp. 508-509, and in 1969 in Surgery of the Stomach and Duodenum by Harkins and Nyhus, 2nd edition, pp. 629-634. Since that time it has been possible to demonstrate on the basis of 1200 operated cases as well as animal experiments that the new technique we introduced represents a successful, nonresecting surgical treatment of gastric and duodenal ulcers. It is important to have a long series of clinical cases from the same source, because it is not until a large number of individual observations have been collected concern ing complications of diagnosis, indications and technique that is it possible to analyse the relationships between them.

The Current Issues in Medicine series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global pandemics, patent law, immunotoxicology, ethics, theranostics, big data, artificial intelligence, novel imaging tools, combination drug products, and novel therapies. Volumes 1 and 2 in this series are focused on current issues in basic medical science, subjects that are fundamental to the practice of medicine. Specifically, volume 1 covers biochemistry, genomics, physiology, and pharmacology.

of the cholecystogram. 1940 - the first anastomosis for oesophageal atresia by CAMERON HAIGHT in Ann Arbor and the first duodeno-pancreatectomy for pancreatic carcinoma, perfor med by WHIPPLE in New York. In 1943 - again WHIPPLE and his associates carried out the first porto-caval anastomosis at Columbia University and in 1945 - there followed BLALOCK'S anastomosis for Fallot's Tetralogy. In the following years the heart, as the last organ of the human body, became the chief target of surgical therapy. Most of the cardiovascular procedures, which today Fig. 4. New medical center of the Free University in West-Berlin under construction are part of the routine all over the world, originated in the United States or in Canada: in particular the spectacular successes of open heart surgery in hypothermia or extracorporeal circulation and the replacement of cardiac valves and arteries. This was the achievement of many active fellows of the American College of Surgeons with names well-known to all of us. The gradient between the surgical standards of our two countries was regrettably large after the second world war. The longtime isolation, the destruction of our cities, the loss of man-power through two world wars and the emigration following 1933 as well as a considerable brain-drain in more recent years were the main causes."

The author of a number of acclaimed, best-selling surgical atlases has collaborated again with an award-winning artist to produce another invaluable surgical resource. This highly regarded team provide a master-class in the demonstration of surgically relevant anatomy. Masquelet has attained world-renown in particular for his innovative flaps for reconstructive plastic surgery of the limbs, in this book he displays his unrivalled knowledge of surgery of the trunk, head, and neck. Every point of entry in required surgical procedures is described, and every procedure is illustrated with a sequence of drawings, displayed as the surgeon would see them, together with anatomical cross-sections.

Surgery inevitably inflicts some harm on the body. At the very least, it damages the tissue that is cut. These harms often are clearly outweighed by the overall benefits to the patient. However, where the benefits do not outweigh the harms or where they do not clearly do so, surgical interventions become morally contested. Cutting to the Core examines a number of such surgeries, including infant male circumcision and cutting the genitals of female children, the separation of conjoined twins, surgical sex assignment of intersex children and the surgical re-assignment of transsexuals, limb and face transplantation, cosmetic surgery, and placebo surgery. When, if ever, do the benefits of these surgeries outweigh their costs? May a surgeon perform dangerous procedures that are not clearly to the patient's benefit, even if the patient consents to them? May a surgeon perform any surgery on a minor patient if there are no clear benefits to that child? These and other related questions are the core themes of this collection of essays.

Chirurgische Sofortmassnahmen" by G. H. Willital an established classic in a new edition provides valuable orientation for every surgically active physician. The book covers all diseases and accidents which might make emergency surgical intervention necessary. The surgical procedures for each case are systematically structured and presented in a clear and concise manner for rapid consultation."

The introduction of antibiotics has practically eliminated infection of the paranasal sinuses as source of intracranial infeetions. Thoracic surgery has nearly eradieated a for merly fairly frequent source of abseess of the brain, namely infections of the lung, such as lung abscess, bronchiectasia and lung gangrene. Gunshot wounds of the head are of course a very important course of brain abseess and meningitis, but in civilian practice fortunately rare. Complieated fractures of the vault and fractures of the base of the skull are at present the most important source of intraeranial infection, and are likely to increase in importance due to ever increasing frequeney of motor accidents. Metastatic brain abscess originating from a foeus of infection of the tonsils or from other lesions anywhere in the body are on the whole rare. This source of infection must be considered to be of minor importance. These faets are clearly reflected in Dr. IRSIGLER'S monograph. There is an abundance of material of traumatic abscesses both due to gunshot wounds and to pcaee-time acci dents involving the vault, the base of the skull and the paranasal sinuses, which is exten sively documented by case histories and weil chosen illustrations.

Die neueste Ausgabe des Atlas of Gastroenterology enthalt umfassendes Bildmaterial, das einen besonders aussagekraftigen UEberblick uber die wichtigsten gastrointestinalen, pankreatischen und hepatobiliaren Erkrankungen vermittelt. Alle Erkrankungen des Magen-Darm-Trakts, von Leberabszessen uber endokrine Neoplasmen der Bauchspeicheldruse bis hin zu Motilitatsstoerungen der Speiseroehre, werden anhand von endoskopischen und transabdominalen Ultraschallbildern, Computertomographien, Magnetresonanzbildern, Radionuklidbildern, Angiogrammen und hochaufloesender Manometrie dargestellt, erganzt um Hinweise zur Histopathologie und Zytologie. Der Atlas enthalt uber 2000 aussergewoehnliche Bilder, geordnet nach Krankheitsbild und Therapieansatz, die auch histopathologische Praparate, MRT- und CT-Scans, Endoskopie, EUS und Bilder von offenchirurgischen Eingriffen umfassen. Mit einem hervorragenden Redaktionsteam und 200 Autoren fur die einzelnen Kapitel, bei denen es sich jeweils um international anerkannte Experten in ihren Fachgebieten handelt, richtet sich Yamada`s Atlas of Gastroenterology an eine breite Leserschaft, von Studierenden uber Assistenzarzte, Stipendiaten und AErzte in Ausbildung bis zu Klinikarzten, Professoren und anderen Medizinexperten. Vielbeschaftigte AErzte in Ausbildung oder Klinikarzte, die sich eine schnelle Einfuhrung in das Spektrum der gastroenterologischen Erkrankungen wunschen, finden in Yamada`s Atlas of Gastroenterology eine praktische und hilfreiche Darstellung der haufigsten Erkrankungen mit einer prazisen, umfassenden Erlauterung der wichtigsten Punkte.

TRANSCATHETER MITRAL VALVE THERAPIES An essential survey of the advancing field of transcatheter mitral valve repair and replacement Minimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapy--though they are getting closer and closer to this goal. Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvements to be made in repair and replacement procedures, as well as the adjunctive use of imaging and pharmacologic therapies. This ground-breaking text: Provides detailed explanations of transcatheter repair, transcatheter replacement, and adjunctive procedures Features chapters on the use of imaging to aid in patient selection, procedure planning, and intra-operative guidance Discusses the importance of minimally invasive approaches for mitral valve repair Examines anticoagulation following transcatheter mitral valve interventions Outlines the possible future of transcatheter mitral valve therapy Transcatheter Mitral Valve Therapies is an important, up-to-date resource for interventional cardiologists, as well as all clinical researchers and practitioners seeking information on this vital and developing treatment.

Evgeniy Perelygin -- a surgeon who is known to his friends as Perya -- has managed to capture the funny, the amusing, and the ridiculous aspects of what surgeons do and think. Yes, surgeons take their profession very seriously and their patients even more so. But, what is true in any aspect of human life is also true for surgery -- there is always something to laugh about, or even ridicule. And this includes, above all, surgeons themselves! In each of these cartoons lurks the kernel of a basic surgical truth. This truth has been blown up, distorted, and exaggerated, but remains at the heart of the picture. Each picture has a legend describing the situation, which is followed by an aphorism, quote, or comment. This book is essentially for surgical eyes -- they are all cutting edge, and will have the reader in stitches. Readers may also wish to use the images to enliven PowerPoint lectures!

Offering unparalleled coverage of this key area, Surgery of the Salivary Glands provides an in-depth, authoritative review of salivary gland disease and treatment. International experts from otolaryngology-head and neck surgery, oral and maxillofacial surgery, and many other disciplines discuss all aspects of surgery and medicine, including anatomy, physiology, histology, pathology, imaging, sialendoscopy, and tumor surgery. Both in print and on video, this innovative, superbly illustrated reference is an ideal resource for physicians in residency or fellowship training, in clinical practice or in academic medicine. Provides comprehensive coverage of salivary gland surgery, including recent developments such as IgG4-related diseases, robotics, tissue engineering, refinements in sialendoscopy, lithotripsy, minimally invasive surgery for neoplasms, new classification systems, and more. Features state-of-the-art discussions of sialendoscopy for stones and stricture, extracapsular dissection, robotic approaches, and conventional salivary gland surgery. Offers access to nearly 60 videos covering salivary gland imaging; the full spectrum of sialendoscopy, including complications; laser fragmentation of salivary stones; minimally invasive approaches; and many more. Includes contributions from global leaders in the fields of otolaryngology-head and neck surgery and oral and maxillofacial surgery, led by Dr. Robert Witt, who brings unsurpassed depth of scientific understanding to this topic. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

The long-awaited companion to the award-winning Browse's Introduction to the Symptoms and Signs of Surgical Disease; this book explains clearly how the pathological features and extent of the disease dictate the necessary diagnostic investigations and treatment. Each chapter will include 3 sections: (1) Relevant Pathology - a brief description of the important pathological features of the disease relevant to the clinical diagnosis, the investigations and treatment. (2) Investigations - covering significant diagnostic clinical findings; radiological, biochemical, haematological, immunological, and pathological investigations, and genetics. The relevance of the investigations will be clearly defined, whether they confirm the diagnosis, or detect the local extent of the disease, the distant spread of the disease, or other systemic effects of the disease. The work will also cover investigations for detecting other diseases relevant to management; and investigations that help exclude confusing differential diagnoses. (3) Treatment - to review all aspects of management; this section will summarize the diagnostic information required to plan management: it will describe each method of treatment available, discuss the indications for each treatment, describe any special preparation and pre-treatment care, any post-treatment care and the complications of treatment, enumerate the results of treatment, and provide a management plan. The 2-book set will provide all the information necessary for the clinical years of undergraduate study, through to surgery at foundation years 1 and 2, planning for the MRCS exams, and beyond.

This book fills a gap in providing specialist information on orthopaedics and trauma occupational therapy. Its contributors bring together information on the aetiology, surgical input and the occupational therapy intervention appropriate to this client group. It is divided into two main sections, the first being orthopaedics and the second orthopaedic trauma. The first part is further subdivided to cover lower limb surgery, upper limb surgery, spinal conditions, and paediatric orthopaedic conditions. In Part two, principles of fracture management are covered, followed by pelvic and acetabular reconstruction, hand injuries and traumatic amputation.