Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients' preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.

This volume provides a comprehensive, state-of-the art review of the management of pancreatic lesions. The book reviews the differential diagnosis and pathology of different pancreatic lesions, profiles new advances in endoscopic evaluation, highlights new perspectives about imaging modalities, describes current treatment strategies and provides an algorithmic approach to management of pancreatic tumors. Recently published literature is placed in context with current management recommendations. The text also discusses the latest advances in minimally invasive techniques, such as Endoscopic Retrograde Cholangio-Pancreatography (ERCP) and Endoscopic Ultrasound (EUS). Written by experts in their fields, Pancreatic Masses: Advances in Diagnosis and Therapy is a valuable resource for gastroenterologists, surgeons and internists that helps guide patient management and stimulate investigative efforts.

Specialists from around the world have contributed to this unique textbook on the surgical skills essential for the urgent treatment of craniofacial injuries caused by war and terrorist incidents. It explores a wide range of considerations including how to work with limited resources and logistical problems, preparation for terror attacks, preservation of sight and cosmetic appearance, and also features a simulation training module proven to be academically successful and economical to run. The content is ideal for all nonspecialist clinicians and students of medicine, dentistry and nursing, and also for teaching programmes involving the psychopathology of trauma.

This atlas is the first book on the use of high-resolution ultrasound to assess breast implants and identify the various potential breast implant-related complications, which are frequently asymptomatic. The aim is to provide radiologists, breast surgeons, plastic surgeons, and other medical staff with a comprehensive guide of high clinical value during not only the diagnostic but also the treatment process. To this end, a wealth of ultrasound images and videos are presented, along with surgical photos and videos and pathological findings. The coverage includes the role of ultrasound in the management of breast implant-associated anaplastic large cell carcinoma, with explanation of its value in distinguishing the type of implant shell, which is highly relevant in this disease. A concluding chapter presents a large series of instructive cases. The author has extensive experience in breast surgery and has been collecting implant-related data using high-resolution ultrasound, including data on the diagnosis of side effects, for more than a decade.

This book offers a detailed, practical guide to incorporating minimally invasive cosmetic surgery into dental practice. Chapters thoroughly examine all aspects of using these materials in practice, and present step-by-step techniques for injecting and placing neurotoxins and fillers, with specific recommendations for product selection and in-depth information on case management. Anatomical drawings and clinical photographs depict the procedures and concepts described. From patient evaluation, treatment planning, and product selection to techniques, managing complications, and marketing the service, Neurotoxins and Fillers in Facial Esthetic Surgery provides a complete resource for using these techniques in practice. Coverage encompasses facial anatomy, neurotoxins, cosmetic fillers, hyaluronic acid dermal fillers, Radiesse(TM) calcium hydroxylapatite injectable filler, pearls and pitfalls, and how to build your practice. Offers a complete but easy-to-use-reference on all aspects of how to set up a minimally invasive cosmetic facial surgery service within an oral and maxillofacial surgery practice Surveys the range of products available in detail from an objective viewpoint Presents how-to techniques for injecting and placing neurotoxins and fillers Neurotoxins and Fillers in Facial Esthetic Surgery is an essential reference for any oral and maxillofacial surgeon or general dentist wishing to add minimally invasive cosmetic surgery to their repertoire.

Basierend auf Erfahrungswerten aus über 30.000 Operationen im Kaiserin-Elisabeth-Spital wird in dem Band die Schilddrüsenchirurgie dargestellt. Beschrieben werden die Entstehung des Wiener Behandlungszentrums, der Wandel von Diagnose und OP-Verfahren sowie die Verbesserung der Ergebnisse. Mit Anleitungen zur Schilddrüsenchirurgie, Skizzen und Fallbeispielen sowie fast 200 Abbildungen. Qualitätsindikatoren werden anhand von Grafiken und Tabellen veranschaulicht. Das Werk vermittelt wertvolle Anregungen für das Qualitätsmanagement in der Chirurgie.

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental interventions. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. The content is structured in six sections. The first deals with ethical, regulatory, and scientific considerations. Chapters in this section include US and international regulatory considerations, and optimization of anesthesia and analgesia. Part two is dedicated to the principles of anesthesia and analgesia with chapters covering topics in a non-species-specific way, but with a slant towards laboratory animals, including relevant pharmacology of the agents. Part three covers Anesthetic equipment and monitoring. Section four deals with periprocedural care including dedicated chapters to the assessment and management of pain in laboratory species. Part five provides practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. Part six closes the book with special topics covering management of chronic pain, fetus and neonate interventions, considerations for in-vivo imaging and the study of pain. Anesthesia and Analgesia in Laboratory Animals is the complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs, and researchers who utilize animals in biomedical research.

The multi-authored, multi-institutional, and multi-specialty-based text is designed as a valuable resource for surgeons working on the maxillofacial region. Meant to be a clinically based history of the past, the present, and the future of the field, this is a one-of-a-kind text that will cater to a variety of professions: from oral & maxillofacial surgeons, plastic and reconstructive surgeons, otolaryngologists - head and neck surgeons, cosmetic surgeons and the general dental practitioner. The History of Maxillofacial Surgery: An Evidence-Based Journey is divided into three sections for ease of understanding: The first section gives an overview of the early history; the second section provides a discussion of conventional procedures; and the third section gives a history of advanced procedures and techniques. By understanding the fundamental procedures and techniques of the field, practitioners can continue to further the field by building upon the past. Including historic case studies paired with real patient photos, this text details why professionals do what they do today with insight directly from the clinic. To provide a unique perspective the book is edited by three individuals at different stages of their careers. Each chapter is authored by a young surgeon paired with a seasoned surgeon.

A comprehensive, state-of-the-art contribution to a field that is rapidly developing, The Behavioral Consequences of Stroke provides a broad overview of the cognitive and neurobehavioral effects of stroke. As attention to paralysis and the more obvious physical disabilities stroke patients incur expands, greater attention is being paid today to the cognitive and neurobehavioral complications that impact stroke morbidity and even functional neurological recovery in patients. Written by an international panel of experts and edited by a neurosurgeon and by a cognitive neuroscientist, this unique title addresses the full range of issues relevant to the field, including epidemiology, general treatment, sensorimotor control after stroke, post-stroke aphasia, memory loss after stroke, post-stroke depression, the role of imaging after a stroke, and an update on some stroke clinical trials, to name just some of the areas covered. Illuminative and an influential addition to the literature, The Behavioral Consequences of Stroke will serve as an invaluable resource for neurologsits, neurosurgeons, physiatrists and other physicians, as well as physical, speech and occupational therapists, nurses, psychologists, and other professionals.

This book is a concise guide to basic techniques in dermatologic surgery. Designed as a ‘how to’, quick reference text with a bullet point format and emphasis on demonstration, the book is invaluable for trainee and practising dermatologists. Beginning with instruction on patient evaluation, anaesthesia, instruments and suturing, the following sections cover skin biopsy, and different surgical techniques including cryosurgery, cyst removal, Mohs surgery, and skin grafts. Two chapters are dedicated to laser surgery for lesions and tattoo removal. The final chapters discuss aesthetic procedures such as chemical peels, neuromodulators, fillers, and treatment of rhinophyma, concluding with detail on biopsy and surgery of the nail. Authored by recognised, US-based expert Glenn Goldman, this book is highly illustrated with surgical photographs and diagrams. Key points Guide to basic techniques in dermatologic surgery for trainee and practising dermatologists ‘How to’, quick reference text, presented in bullet point format for easy understanding Authored by recognised, US-based expert in the field Highly illustrated with surgical photographs and diagrams

AErzte gelten als Halbgoetter in Weiss und Chirurgen sind fur viele so etwas wie die Elite der AErzteschaft. Der Chirurg hat das Image eines Machers, er fasziniert, sein Alltag erscheint vielen unheimlich spannend und spektakular. Schliesslich verabreicht er keine Pillen, nein, er schneidet in die Haut - und das ist immer eine Grenzerfahrung. Dieses Buch ermoeglicht einen Blick hinter die hermetisch verschlossenen Turen der OP-Sale. Was geht dort vor sich? Welche Fahigkeiten muss der Operateur besitzen? Wie fokussiert er sich und wie bekommt er seine Emotionen in den Griff? Fragen wie diese werden in den dreizehn Kapiteln des Buches beantwortet - und das nicht in Form theoretischer Abhandlungen oder fiktiver Geschichten, sondern anhand ganz konkreter Erfahrungen des Autors, die er in seiner uber 40-jahrigen beruflichen Laufbahn sammeln durfte. Und es zieht Parallelen zum Leben ausserhalb der Krankenhauser, da letztlich in jedem Unternehmen und fur jeden Menschen dieselben Fahigkeiten und Eigenschaften wichtig sind: sich fokussieren und Ziele setzen, handeln und Druck von aussen managen, innovativ sein und das Team einbinden. Mit den konkreten Handlungsanleitungen gelingt die Umsetzung ganz einfach im Beruf oder privaten Alltag.

Aesthetic Orthognathic Surgery and Rhinoplasty prasentiert die orthognathe Chirurgie aus asthetischer Sicht und behandelt die Bereiche Analyse, Diagnose, Behandlung, virtuelle 3D-Planung und begleitende Verfahren. - Prasentiert klinische Informationen pragnant und zuganglich. - Reich illustriert mit mehr als 1.000 klinischen Aufnahmen. - Begleitende Website mit Videos zu chirurgischen Verfahren.

Recent trends in medicine have pushed many gynecologic procedures to the outpatient setting, whether in-office, in small medical ambulatory surgery centers, or in procedure rooms. Office-Based Gynecologic Surgical Procedures covers both basic and advanced procedures, from biopsy and saline ultrasound to cystoscopy. It answers the "How?", "What?", and "When?" of setting up, preparing for, and confidently performing office procedures. While appropriate training and certification in these procedures such as cystoscopy and hysteroscopy is needed, this book is an excellent resource for advice and tips on how to safely transition from the technique used in the operating room. It also provides the necessary algorithms and in-depth instructions pertinent to performing these types of procedures effectively in the office setting. A chapter on patient safety in the office is also included. Office-Based Gynecologic Surgical Procedures is ideal for established OBGYNs in practice who want to expand their range of procedures offered in-office, fellows in Women's Health, advanced nurse practitioners, recent OBGYN residency graduates, and family medicine physicians eager to familiarize themselves with women's health procedures.

Peritoneal dissemination is a common route of cancer metastasis. The benefit of administering chemotherapy directly into the peritoneal cavity is supported by preclinical and pharmacokinetic data. In comparison to intravenous (IV) treatment, intraperitoneal (IP) administration results in a several-fold increase in drug concentration within the abdominal cavity. There is now growing evidence from clinical studies showing a survival advantage for IP chemotherapy in various tumor typies, including ovarian, gastric and colorectal cancer. However, while the use of IP chemotherapy is slowly gaining acceptance, it is not universal, largely due to the greater toxicity associated with this approach. Moreover, efficacy of IP chemotherapy is limited by poor distribution within the abdominal cavity and by poor tissue penetration. A new way of IP chemotherapy is the application of cytotoxics in form of a pressurized aerosol into the abdominal of thoracic cavity. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied through laparoscopic access using two balloon trocars in an operating room equipped with laminar air-flow. In a first step,a normothermic capnoperitoneum is established with a pressure of 12 mmHg. A cytotoxic solution (about 10% of a normal systemic dose) is nebulized with a micropump into the abdominal cavity, and maintained for 30 min. The aerosol is then removed through a closed suction system. Applying an aerosol in the peritoneal cavity allows a homogeneous distribution of the chemotherapeutic agent within the abdomen. Furthermore, an artificial pressure gradient is generated that overcomes tumoral interstitial fluid pressure, an obstacle in cancer therapy. This results in a higher local drug concentration compared to conventional IP or IV chemotherapy. At the same time the plasma concentration of the chemotherapeutic agent remains low. In first clinical studies with limited number of patients in ovarian, gastric and colorectal cancer, as well as peritoneal mesothelioma, PIPAC has obtained encouraging tumor response rates and survival, with a low-side effects profile. Larger clinical trials are currently ongoing to examine if these data can be reproduced and extrapolated to other situations.

"Imaging and Technology: Principles and Clinical Applications"is a practical and user-friendly consolidated source book for urologists, and urologists in training, regarding the basic science of imaging modalities used on a day-to-day basis in urological practice. Similarly, the intention is to provide an introduction to the technology that is used in the practice of urological surgery and the management of urological patients in the clinical setting. This knowledge level is appropriate for certification for independent consultant practice in urology in the UK. The book is also valuable to urologists and urological trainees outside of the UK and in other surgical specialities."

In this work, Dr. Rosen, who has "changed the way most surgeons work on the jaw and chin" describes his own aesthetic techniques of balanced and proportioned soft facial tissue correction. This volume will be extremely useful to the surgeon interested in the aesthetics of plastic, maxillofacial, and orthodontic surgery.

Primum non nocere... The fact that a surgical procedure can leave any kind of pain casts a shadow over this tenet, which is seen as the basis of medical practice and anchor of its principle ethic... It is all the more surprising in that medicine has only paid attention to this paradoxical chronic pain situation for the past few years. Clarifying the knowledge acquired in this field has become all the more urgent for any care-giver today confronted by a legitimate request from patients: Why and how can a surgical procedure, which is supposed to bring relief, leave behind an unacceptable sequela? This is the approach which the contributors to this new subject of major clinical interest invite you to follow as you work your way through this book.

Minimally invasive cardiac surgery(MICS) is an integral component of every future cardiac surgeon's training. There continues to be a growing global demand towards less invasive surgical techniques. Both cardiologist and cardiac surgeon form "heart teams" to provide patients with novel, minimally invasive procedures, with all their benefits. Less invasive techniques are often complex and require special knowhow and skills. This book offers an innovative approach to learning, utilizing QR code technology, which refers the reader to essential audio-visual material, which, along with the didactic text, focuses on practical aspects of minimally invasive cardiac surgery. In modern Heart Teams, and with the advent of the hybrid era, surgeons will only be able to survive if they have state-of-the-art skills in less invasive technologies, which can be incorporated in the hybrid theatre and/or trans-catheter arena. This text accompanies the surgeon along this path, and provides clinical advice and practical solutions, beyond the necessary basic knowledge. Which courses to visit, which videos to watch, which centres to join for serious training? How best to exploit public and multimedia? How to consent a patient into a MICS procedure? How to set up a MICS program or practice? In the era of value driven outcomes, and a shift towards shorter and better patient journeys, MICS is a skill that no heart surgeon can be without. Minimally Invasive Cardiac Surgery: A Practical Guide is a teaching resource, reference book and manual written by surgeons who both operate and teach the procedures described within. Provides access to online resources via QR codes Includes links to videos and the e-version of the text Acts as a gateway to a huge choice of minimally invasive cardiac surgery materials

In this volume an account is given of the technologies relevant to the detection of sentinel lymph nodes in the context of surgical oncology. This is a rapidly and evolving field, and the clinical applications discussed in this volume are exciting and important. A multidisciplinary team was assembled to discuss this subject in the light of direct experience gained by each of the groups in the previous 12 months. Clinical case material is presented and the methodology of sentinel lymph node imaging and detection is discussed in detail. The authors have assembled in a single volume a significant amount of personal data and a comprehensive literature review which will serve as a single reference and teaching source for all those interested in this critical technique relevant to the management of large numbers of patients in surgical oncology.

"The Handbook of Dermatologic Surgery"incorporatesthe most cutting edge technology applicable to dermatologists and dermatologic surgeons today. Designed as a reference guide for dermatologic surgery and aesthetic procedures, it disseminates key scientific information in an easy-to-use pocket book.

This handbook is designed to be readily transportable for dermatologists and dermatologic surgeons, as well as those in training, dermatology residents and fellows, and medical students rotating through dermatology. "

DDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analysis of symptoms and on knowledge of the individual patient and family. This series follows that on Problems in Practice which was con cerned more with diagnosis in the widest sense and this series deals more definitively with general care and specific treatment of symp toms and diseases. Good management must include knowledge of the nature, course and outcome of the conditions, as well as prominent clinical features and assessment and investigations, but the emphasis is on what to do best for the patient. Family medical practitioners have particular difficulties and advantages in their work. Because they often work in professional isolation in the community and deal with relatively small numbers of near-normal patients their experience with the more serious and more rare conditions is restricted. They find it difficult to remain up-to-date with medical advances and even more difficult to decide on the suitability and application of new and relatively untried methods compared with those that are 'old' and well proven. vii Their advantages are that because of long-term continuous care for their patients they have come to know them and their families well and are able to become familiar with the more common and less serious diseases of their communities.

Although distant metastases are the most dreaded situation in the evolution of cancer of every organ, the medical literature has surprisingly given little attention to the anatomical relationship between the primary tumor and metastasic sites. Only risk factors, treatment possibilities, and survival results are extensively examined.
Stimulated by the occurrence in his practice of some puzzling and unexpected metastases, the author reviewed more than 12,000 references. He looked for anatomical relationships highlighting the relation between the location of the primary tumors and the particular patterns of metastasis observed. It would seem that the pathways and flows' are apparently a more decisive factor in the implantation of the metastases than the seed and soil' properties of the cancer cells and the metastatic site.
Aided by his colleague Dr. T. Geukens, M.D., the author includes original anatomical drawings, illustrating the sometimes unexpected pathways the cancer cells follow in order to reach the organs where they will become lodged and give rise to metastatic tumors. The subject has apparently not been exhausted in the literature and several ideas are given for further research.