The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are explained. These disorders occur among many people and include sensorineural hearing loss (SNHL), sudden deafness, senile deafness, noise-induced deafness, tinnitus, dizziness-vertigo, and Meniere's disease. In Japan alone, there are more than 6 million deaf patients including those with middle-range deafness. There is currently no effective treatment, and regardless of the underlying cause, the damage has been considered irreversible. However, the results of recent research show that these patients actually can recover. The study of hair cells, spiral ganglion neurons, and stem cells for inner ear diseases such as SNHL, tinnitus, dizziness, and vertigo is at the forefront of regenerative medicine and may provide solutions to some of these problems. The information presented here makes this book a valuable professional reference work for all doctors and researchers in the field of otolaryngology who focus on regenerative treatments for inner ear diseases.

The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends the evidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.

This volume presents the most recent developments in diagnosis and treatment of patients with gastroesophageal reflux disease (GERD) and those who continue to be refractory to conventional GERD therapies. The book delineates the role of newly developed endoscopic therapies in GERD and outlines the best candidates for surgical fundoplication. Topics as the risks associated with GERD, lifestyle modification in GERD and the role of H2RA and proton pump inhibitor therapy in treating reflux disease are also explored. Written by authorities in the field, Diagnosis and Treatment of Gastroesophageal Reflux Disease is a concise yet comprehensive resource that is useful for primary care providers, gastroenterologists, pulmonologists, surgeons and ENT specialists.

This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it’s management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.

Endocrinology, and diabetes care in particular, is a dynamic field where clinicians must translate new evidence into clinical practice at a rapid pace. Designed in an engaging, case-based format, Endocrinology and Diabetes: A Problem Oriented Approach offers a wide range of thought-provoking case studies that reflect contemporary, challenging, hands-on clinical care. Further, by providing a list of specific clinical problems, this format offers the reader a more convenient and pointed way to solve precise clinical problems in a timely manner. Developed by a renowned, international group of experts, this comprehensive title covers the most common clinical problems in endocrinology and diabetes and should be of great interest to endocrinologists, diabetologists, internal medicine physicians, family physicians, fellows, and residents.

This book is devoted solely to the tricuspid valve and its role in congenital heart disease. Tricuspid valve anomalies are part of the pathological spectrum in various congenital heart diseases, including Ebstein anomaly and tricuspid valve dysplasia, with different pathophysiology and clinical implications. This book covers all relevant aspects of such anomalies, including diagnosis, therapy and follow-up. Further topics addressed include the way in which the tricuspid valve may become the "systemic" valve in some congenital diseases, with important consequences and the involvement of the tricuspid valve in the right-sided heart complications often seen in adults with congenital heart disease. All of the chapters are written by internationally recognized experts and are designed to deliver state of the art knowledge of practical value. This book will be an important addition to the library for surgeons, cardiologists and other practitioners involved in the management of patients with congenital heart disease.

Peripheral, Head and Neck Surgery is part of the series: Surgery -Complications, Risks and Consequences edited by Brendon Coventry.

One of the greatest challenges for mechanical engineers is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, biomedical sciences, and medicine. This book is an opportunity for computational biomechanics specialists to present and exchange opinions on the opportunities of applying their techniques to computer-integrated medicine. Computational Biomechanics for Medicine: Models, Algorithms and Implementation collects the papers from the Seventh Computational Biomechanics for Medicine Workshop held in Nice in conjunction with the Medical Image Computing and Computer Assisted Intervention conference. The topics covered include: medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, injury mechanism analysis, implant and prostheses design, and medical robotics.

Despite tremendous recent advances in the treatment of most malignancies, there remain several critical questions for each cancer. This particularly true for the surgical management of solid-organ malignancies. Comparative effectiveness is a relatively new term which encompasses the age-old concepts of how best to treat cancer patients. Comparative effectiveness is defined as the direct comparison of healthcare interventions to determine which work best for which patients when considering the benefits and risks. The Institute of Medicine has defined comparative effectiveness research(CER) as the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care. CER is certainly best done with well-conducted randomized controlled trials. Unfortunately, clinical trials are not always feasible owing to the impracticality of conducting the trial, the considerable cost, and the time required to complete the trial. These challenges are even more pronounced with respect to surgical treatment. Thus alternative approaches may need to be considered in order to address pressing questions in the care of the oncology patient. These approaches may include well-conducted retrospective cohort studies from cancer registries and other data sources, decision and cost-effectiveness analyses, and other novel methodologies. This book lays out the current critical questions for each major malignancy and proposes approaches to gain answers to these pressing questions.

Tissue diagnosis in surgical pathology is the most important determinant of patient outcomes in oncology and other medical conditions. An appropriate diagnosis of a tumor correctly determines the necessary therapy for that patient. Error Reduction and Prevention in Surgical Pathology focuses on how errors happen, the best systems to detect errors and the best systems to prevent errors. As with any form of testing, the test cycle in surgical pathology can be divided into pre-analytic (collection and handling of specimens), analytic (the actual determination of disease or other diagnostic information) and post-analytic (generation of reports and distribution). Error can occur anywhere in the process and all of these steps must be performed optimally so that the correct diagnosis is made and delivered. Error Reduction and Prevention in Surgical Pathology serves as an essential guide to a successfully managed laboratory and contains all relevant information needed to manage patients and deliver the best diagnosis.

This book provides an overview on the critical role of diagnostic imaging in the assessment of patients with suspected alimentary tract perforation, an emergent condition that requires prompt surgery. With the aid of numerous high-quality images, it is described how different imaging modalities, including plain film X-ray, ultrasonography and multidetector row computed tomography (MDCT), permit correct diagnosis of the presence and cause of the perforation and of associated pathologies. Particular attention is paid to MDCT, with full description of its role in a range of scenarios at various levels of the alimentary tract. Imaging of GI tract perforation in different patient groups, such as pediatric patients, the elderly and oncologic patients, is also addressed. This volume will greatly assist residents in radiology, radiologists and physicians who are daily involved in the management of patients with clinically suspected alimentary tract perforation.

This is a timely and informative updated edition for all health care providers challenged with helping patients manage weight. Similar to the well-reviewed first edition, this updated title is directed toward individuals who wish to read further about targeted topics, rather than find an introduction to the field. This second edition again provides insights into recent scientific advances in obesity research and provides the most up-to-date instruction about current treatment issues and strategies for both adults and children. While several of the chapters are no longer relevant from the first edition, other topics have emerged as interesting and current. This edition will keep the two-section format of Physiology and Pathophysiology and Clinical Management, but it increases the first section to 10 chapters and reduces the second section to 12 chapters. The plan is to keep this edition in the range of about 350 to 400, maximum, printed pages. The volume is again divided into two parts. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Expert authors discuss pathways that control food intake, energy expenditure and peripheral nutrient metabolism, including a look at the emerging evidence of the role of adipose tissue as an endocrine organ. Part 2 covers all the key issues central to clinical management, including recent developments in the epidemiology of obesity, assessment of the obese patient, behavioral strategies in weight management, dietary modification as a weight management strategy, physical activity as a weight management strategy, weight loss drugs, surgical approaches to obesity and other important clinical topics. An essential, practical text that sorts, synthesizes and interprets the latest information on obesity-related topics, this second edition will be an essential resource for clinical endocrinologists and other health care providers across a broad spectrum of specialties.

The Clinician's Guide to Swallowing Fluoroscopy is a comprehensive resource for all dysphagia clinicians. This beautifully-illustrated text is intended for SLP, ENT, radiology, GI, and rehabilitation specialists interested in swallowing and addresses the need for an up-to-date, all-inclusive reference. Topics covered include radiation safety and protection, fluoroscopic oral, pharygeal, and esophageal phase protocols and abnormalities, and objective measures of timing and displacement.

PEDIATRIC CARDIAC SURGERY Explore the leading textbook of pediatric cardiac surgery in this easy-to-read and beautifully illustrated volume The field of pediatric cardiovascular surgery includes not only heart surgery for infants and children, but also adult heart surgery to correct congenital heart defects which have been present since birth. As infant mortality from heart defects declines and patients with congenital heart defects live increasingly long and healthy lives, new challenges emerge and as such, the need for introductions to this life-saving field has never been greater. For more than thirty years, Pediatric Cardiac Surgery has met this need with an accessible, comprehensive textbook used by professionals at every level of the field. Featuring full color illustrations, this book offers an introduction to the science of cardiovascular development before moving to detailed analysis of defects in different areas of the heart and their corrective procedures. This updated fifth edition incorporates the latest science to remain the indispensable work on this subject. In Pediatric Cardiac Surgery, 5th edition readers will also find: Contributions from over 75 national and international experts in the field Stunning anatomical illustrations by Rachid Idriss New chapters reflecting cutting-edge research, as well as new material throughout pertaining to cardiac imaging and medical education Pediatric Cardiac Surgery is essential for pediatric and adult cardiac surgeons, cardiologists, and all medical professionals working with pediatric or adult cardiovascular patients.

One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences and medicine. The Computational Biomechanics for Medicine series provides an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements. This 5th edition comprises nine of the latest developments in both fundamental science and patient-specific applications, from researchers in Australia, New Zealand, USA, UK, France, Ireland and China. Some of the interesting topics discussed are: cellular mechanics; tumor growth and modeling; medical image analysis and both patient-specific fluid dynamics and solid mechanic simulations.

Neurointervention in the Medical Specialties is a first-of-its-kind reference that serves as a bridge between the neurointerventionalist and the physicians who most frequently look to these specialists for answers to some of the most intractable problems they face. Providing background on the wide range of diseases treated through neurointervention along with the indications and alternatives to such treatments, this landmark title is grouped into four parts: an introduction to the tools and anatomical structures that are integral to the field; disease processes most often encountered by neurologists, cardiologists, and vascular surgeons; those diseases more frequently treated by neurosurgeons; and finally those diseases first seen by several other specialties including ophthalmologists and head and neck surgeons. Importantly, each chapter includes details of neurointerventional technique and case discussions that are sufficiently detailed to provide a treatment template and guidance to neurointerventionalists in training and practice. At the same time, the descriptions provide referring physicians with insight into how neurointerventional procedures are performed. Finally, there are several concluding, thought-provoking chapters that examine what new opportunities await the field of neurointervention on the horizon. Neurointervention in the Medical Specialties is a major contribution to the literature and invaluable resource for all clinicians and researchers interested in this exciting field.

Oral Cytology: A Concise Guide provides a state-of-the-art review of the major issues specific to the field of oral cytology. The sections of the book have been structured to review the complexities of sample collection, manual/automated analysis, pitfalls, gray zones and controversies in diagnosis, as well as, issues not covered by other available materials. Recent advancements in ancillary techniques like DNA ploidy, image analysis and molecular biology are discussed in detail. This useful text is extensively illustrated with patient and microscopic pictures, which will further highlight the clinical application. Throughout the text, simultaneous inclusion of both cytologic and histologic images will allow cyto-histological correlation. Readers will find descriptions of techniques offering greater simplicity, speed, patient comfort and cost effectiveness, as well as improved diagnostic precision. This bench-side reference is a unique and valuable resource in the field of oral cytology, both for those currently in training and clinicians dealing with the diagnosis of oral lesions.

Ziel der heutigen SportorthopAdie und Sporttraumatologie muA es sein, verletzten Sportlern die RA1/4ckkehr auf ihr eigenes Leistungsniveau zu ermAglichen. Experten aus der ganzen Welt demonstrieren den aktuellen Stand der arthroskopischen und offenen Stabilisierungsverfahren bei der instabilen Schulter (vordere, hintere und multidirektionale SchulterinstabilitAt), der perkutanen Osteosynthese von Humeruskopffrakturen, der offenen und arthroskopischen Rekonstruktion der RotatorenmanschettenlAsion mit ihren Grenzen und MAglichkeiten, des sekundAren Impingements des Sportlers auf dem Boden einer superioren InstabilitAt, der Endoprothetik des Glenohumeralgelenkes und der SportfAhigkeit mit einer Schulterprothese.

This book on fibroid uterus focuses on surgical challenges in minimal access surgery that a surgeon faces while treating this condition. This book explores the role of various imaging modalities in both diagnosis and planning of the treatment. Various surgical techniques, such as hysteroscopy, laparoscopy, and robotic are discussed which will help readers to understand the pros and cons of each one. Teaching practical tips from experts regarding these procedures, the book aims to help surgeons make clinical decisions while they choose surgical procedures for their patients in various clinical settings. The book highlights both the conservative (techniques of myomectomy) and hysterectomy by various methods for treating fibroids. Key Features How to use various imaging modalities for preoperative evaluation of fibroids Issues in preoperative counseling and consent before surgery for fibroids Overview of surgical treatment of fibroids Individual chapters on practical tips by experts for various surgical techniques used for both myomectomy and hysterectomy Discusses the controversy in morcellation and how to perform it safely Covers the problem of parasitic fibroids that have increased in recent times Discusses issues like breach in endometrial cavity during myomectomy, surgery for adenomyosis, uterine rupture and recurrence after myomectomy When to call it a day and convert from laparoscopy to laparotomy

Practical Procedures in Aesthetic Dentistry presents a comprehensive collection of videos demonstrating clinical techniques in aesthetic and restorative dentistry, and is accompanied by a handbook summarising the key points of each procedure. * Interactive website hosting over nine hours of video * Accompanying illustrated handbook summarising key points * Expert teaching across a comprehensive range of aesthetic and restorative procedures * International team of contributors with clinical and academic expertise

General Surgery Risk Reduction is part of the series: Surgery: Complications, Risks and Consequences edited by Brendon Coventry.

New technologies in 3D printing offer innovative capabilities in surgery, from planning complex operations through to educational purposes and providing alternatives to traditional training with more cost-effective outcomes. This hot topic title synthesizes the most up-to-date information on 3D printing and its application into surgical specialties including, hebatobilliary and pancreatic surgery, vascular surgery, orthopedic surgery, obstetrics and gynecology, cardiovascular and thoracic surgery, and more. Discusses challenges and opportunities of 3D printing across surgical sub-specialties. Covers 3D printing and its application in major surgical specialties, as well as dentistry, transplantation, global surgery, and diagnostic and interventional radiology. Consolidates today's available information on this burgeoning topic into a single convenient resource.

A concise revision guide to the core basic sciences for all surgical trainees preparing for Part A of the Intercollegiate MRCS examination. Covering the essential facts for anatomy, physiology and pathology, with indications of both their clinical relevance and importance. Focusing on the recurring examination themes for initial surgical training, this title is designed for the basic surgical trainee as well as proving useful for those in higher surgical training and for the surgically-inclined, well-motivated student. Covers the essentials of the basic sciences - anatomy, physiology and pathology - for the MRCS examination. Explains the application and clinical relevance of the three sciences. Bulleted text for easy reading and rapid exam preparation. Focused on the common themes of the examination. Clear annotated line drawings to aid learning. 250 new online single-best answer questions in the format of the MRCS Part A examination. Each answer will refer back to text for further reading as required. New OSCE 'Clinical scenarios' at the end of every chapter.

Surgical Pain Management is an essential, step-by-step guide to surgical techniques and the perioperative management of chronic pain patients whose treatment includes implantable therapies. Chapters review the steps necessary for defining a potential candidate for implant and the infrastructure to support the perioperative period and beyond, controversies in approaches for both intrathecal and spinal cord stimulation implants, healthcare education for patients with these devices, neuroaxial drug delivery, electrical stimulation of the peripheral and central nervous system, and a variety of invasive procedures for chronic and cancer pain. Appendices provide supplemental information regarding guidelines, physiology, technologies available, troubleshooting, and documentation required to organize an interventional service. This book details a range of approaches from basic implant therapies to more advanced therapies, making it an ideal companion to an advanced training program in interventional pain management and a useful resource for developing a team that will optimize care for some of the most difficult to treat chronic pain patients.