With detailed contributions from more than 40 leading authorities, this edition comprehensively explores the immunobiology, pathophysiology, and clinicial manifestations of graft-versus-host disease (GvHD), offering sections revealing the most up-to-date research on immune activation and dysregulation, the pathophysiology of target organ damage, and GvHD prevention and treatment. 53 illustrations.

Contents:
1. The Importance of Rhinitis 2. Causes of Rhinitis 3. Making a Diagnosis 4. Examination 5. Investigations 6. Airway Tests 7. Tests of Mucociliary Clearance 8. Imaging 9. Other Tests

Now in its fifth edition, the Oxford Handbook of Emergency Medicine is the essential rapid-reference guide to emergency medicine for everyone from junior doctors to specialist registrars, nurse practitioners, and paramedics. New and improved, the Handbook has been thoroughly revised throughout, with 100 extra illustrations and the latest guidelines and treatment advice, completely overhauled chapters on Medicine, Obstetrics and Gynaecology, and Paediatric emergencies, and new topics on treatment escalation, end-of-life care, and sepsis. Clear and concise, extensively updated, and packed with a host of new X-rays to aid identification and treatment, this Handbook has everything you need to thrive in the demanding world of emergency medicine today.

All subjects have their canon of literature that should be studied before serious students can advance in their chosen fields. Containing papers carefully compiled not merely for their historical importance but also for their contemporary relevance, Classic Papers in Breast Disease is that resource. A team of experts shares their experience in researching, diagnosing, and treating breast disease.
Each chapter contains not just a compilation of papers, but a critical commentary on the papers, their strengths and weaknesses, and their relevance to current practice and research. The commentary, always insightful and straightforward, ranges from theory to practice, from physical to psychological. Each chapter also has a brief introduction to set the scene as the author sees it. All the papers share in common their place as building blocks, as judged by the refraction of history, in the current knowledge base or in current research.

This issue of Hand Clinics, guest edited by series consulting editor Dr. Kevin Chung, will cover Current Concepts in the Management of Proximal Interphalangeal Joint Disorders. Topics discussed in the volume include: Anatomy and biomechanics of the finger proximal interphalangeal joint; Surgical exposure of the proximal interphalangeal joint; Treating proximal interphalangeal joint dislocations; Management of proximal interphalangeal joint fracture dislocations; Proximal interphalangeal joint fusion: indications and techniques; Implant arthroplasty: selection of exposure and implant; Salvaging a failed proximal interphalangeal joint implant; Treatment of proximal interphalangeal joint contracture; Treating congenital proximal interphalangeal joint contracture; Complications of proximal interphalangeal joint injuries: prevention and treatment; and Therapy concepts for the proximal interphalangeal joint, among others.

Contents:
1. The amg ARTHOS and ARTHOS^TInert Coronary Stent Implantation Systems 2. The Antares Starflex Coronary Stent System 3. The AST SLK-view Stent and Delivery System 4. The BeStent2 Stent 5. The biodivYsio AS, OC, SV Stent Range with PC Technology^TTM 6. The Bx VELOCITY^TTM Stent 7. The Carbostent SIRIUS Stent 8. The Cordynamic Apolo Stent 9. The Coroflex and Coroflex Delta Coronary Stent Systems 10. The Duraflex^TTM Coronary Stent System 11. The Express Coronary Stent System 12. The GENIC DYLN Stent 13. The GENIC, GENIC SV and GENIC LV Stent Systems 14. The Genius Coronary Stent 15. The Igaki-Tamai Stent 16. The JOSTENT Coronary Stent Range 17. The Lunar Coronary Stent System 18. The Maeo Stent 19. The Med-X Flexy Stent 20. The Medtronic AVE Modular Stents ^TTM Coronary Stent System 23. The Multi-Link RX PIXEL^TTM Coronary Stent System 24. The Multi-Link RX Ultra^TTM Coronary Stent System 25. The Nexus and Nexus II Stents 26. The NIR and NIRFLEX Coronary Stents 27. The Prolink Stent 28. The ProPass Stent 29. The Coronary R Stent^TTM 30. The Rithron and Rithron-XR Coronary Stents 31. The Seaquest Stent^TTM 32. The Spiral Force Stent 33. The Tsunami Coronary Stent System 34. The Zebra Stent Section II: Drug-Eluting Stents 35. The Background, Rationale for and Current Status of the ELUTES (EvaLUation of paclitaxel Elusting Stent) Trial 36. The Biocompatibles' Drug-Eluting Stents 37. The Boston Scientific Antiproliferative, Paclitaxel Eluting Stents (TAXUS) 38. The Multi-Link TETRA D^TTM Drug-Coated Coronary Stent System 39. The Ohytis DLC (Diamond-Like Carbon) Coated Stents 40. The Phytis Double-Coated Stent 41. The Quaman QuaDDS-QP2 Stent 42. The Sirolimus-Eluting Bx VELOCITY^TTM Stent: Preclinical Data 43. The Sirolimus-Eluting Bx VELOCITY^TTM Stents: Clinical Data

In 1967, after a twin baby boy suffered a botched circumcision, his family agreed to a radical treatment that would alter his gender. The case would become one of the most famous in modern medicine and a total failure. "As Nature Made Him" tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's and one family's amazing survival in the face of terrible odds.

Get all the facts and build your expertise on the fast-growing practice of home hemodialysis The use of home hemodialysis is becoming more popular every year. Home dialysis modalities not only provide more flexibility for patients, they are associated with numerous benefits, including improved cardiovascular parameters and better quality of life. Most dialysis resources tend to focus on in-center hemodialysis with little to no discussion of home hemodialysis. The Handbook of Home Hemodialysis aims to change that with focused, detailed coverage on the topic. This timely, one-of-a-kind resource offers everything you need to build your expertise on the subject. It's also small enough to fit in your pocket and designed to provide accurate, easy-to-find answers on the fly. Clear drawings and illustrations clarify and highlight key information. The Handbook of Home Hemodialysis provides essential information on: The of history home hemodialysis Vascular access Patient recruitment and training Prescribing home hemodialysis Water handling Laboratory parameters/monitoring Emerging benefits Common complications Special populations Remote monitoring Building a home dialysis program, and more

Intragastric balloons are steadily gaining popularity among the medical treatments available for obesity. Their efficacy and safety are reinforced by growing body of evidence obtained around the globe. Intragastric balloons are now considered one of the safest and most effective medical procedures for weight reduction. Additionally, the reduced potential for side effects and low invasiveness (compared to bariatric surgeries) are important considerations. This book is edited by renowned surgeons and endoscopists from Brazil, a country known for its reputation on the field of bariatric endoscopy and surgery. Such reputation is especially valid where the use of intragastric balloons is concerned. These devices, approved by the FDA only in 2015, have been used in Brazil since the 1990s, attesting to Brazilian expertise in the field. This book describes the various types of intragastric balloons used for the treatment of obesity, an alternative to bariatric surgery and other more invasive methods. It addresses their indications, procedures and outcomes, providing readers an overview of the therapeutic options available worldwide. It is divided into seven main sections: I - Introductory Issues; II - Devices; III - Technical Procedures and Related Issues; IV - Acute Complications and Treatment; V - Chronic Complications and Treatment; VI - Special Populations; and VII - Miscellaneous. This structure helps to promote a better knowledge construction and a reasonable flow of ideas throughout the book, guiding the reader from introductory topics to surgical procedures and complications. The book ultimately intends to offer an essential reference guide for all physicians and surgeons interested in the treatment of obese patients. It is intended for both experienced professionals looking for in-depth information and for trainees and residents seeking to broaden their perspectives concerning the treatment of obesity.

The aim of eye muscle surgery is to restore alignment of the visual axes and ocular stability. Albeit compensatory and largely empirical, this surgery can be perfected with a better understanding of the physiopathological mechanisms involved, more detailed semiological analysis, the taking into account of intraoperative data and the use of microsurgical technique. The three parts of this book allow each of these factors to be discussed at length.

As a medical student, Samer Nashef was unofficially blacklisted when he started asking questions about the death rates of more senior surgeons. Since then, he has made his name challenging colleagues to be more open and accurate about the success of the procedures they perform. In The Naked Surgeon, Nashef unclothes his own profession, offering an unprecedented and often controversial view inside the operating theatre. He explains how surgeons can 'game' the system to make their results appear better; why the way a surgeon ties the knot in a single stitch could make a life-or-death difference; and why patients operated on the day before a surgeon goes on holiday are twice as likely to die than those operated on during that surgeon's first day back. Full of eye-opening revelations about the cardiac surgeon's craft, The Naked Surgeon is necessary reading for anybody considering medical intervention now, or in the future.

Orthognathic Surgery: Principles, Planning and Practice is a definitive clinical guide to orthognathic surgery, from initial diagnosis and treatment planning to surgical management and postoperative care. * Addresses the major craniofacial anomalies and complex conditions of the jaw and face that require surgery * Edited by two highly experienced specialists, with contributions from an international team of experts * Enhanced by case studies, note boxes and more than 2000 clinical photographs and illustrations * Serves as an essential reference for higher trainees and practicing clinicians in cranio-maxillofacial surgery, orthodontics, plastic and reconstructive surgery and allied specialties

Modern practical medicine requires high tech in diagnostics and therapy and in consequence in education. All disciplines use computers to handle large data bases allowing individual therapy, to interpret large data bases in form of neuronal signals, help visualization of organs during surgery. This book contains chapters on personalised therapy, advanced diagnostics in neurology, modern techniques like robotic surgery (da Vinci robots), 3D-printing and 3D-bioprinting, augmented reality applied in medical diagnostics and therapy. It is impossible without fast large scale data mining in both: clinical data interpretation as well as in hospital organization including hybrid surgery rooms and personal data flow. The book is based on a course for medical students organized in the editor's department. Every year, around 300 international undergraduate medical students take the course.

'Principles and Practicalities of ENT' ensures that doctors of all levels are well equipped to approach common clinical scenarios encountered in ENT with confidence. Each section covers how to prepare for patients, includes key points in the history and examination, and how best to investigate and manage a wide variety of common ENT presentations and conditions. The material is structured to provide an easy reference including red flag and primary care sections to enable readers to know what to look out for when considering referrals. Inaddition to being a revision tool for medical students, doctors pursuing MRCS (ENT) examinations and higher surgical training in ENT, this book also serves as a useful aid for primary care physicians in their everyday diagnostics and referral practices.

Jones' Clinical Paediatric Surgery provides clear-sighted advice on the surgical options available for young patients. Building on the popular and successful style of previous editions, this fully revised seventh edition employs a systematic approach to the childhood diseases that need surgical treatment. It includes more case vignettes and colour photographs, expanded coverage on the use of imaging, and updated approaches to management including laparoscopic operations. Key subject areas are supported by case vignettes in a familiar format similar to what might appear in an OSCE viva. Jones' Clinical Paediatric Surgery is the ideal guide for paeditricians, surgeons and trainees, as well as primary care physicians, junior doctors and medical students.

This useful reference provides up-to-the-minute coverage of every aspect of valvular heart disease-presenting etiology, pathophysiology, and symptomatology in detail as well as current methods of diagnosis and treatment.
Examines specific problems in valvular heart disease such as endocarditis, pregnancy, arrhythmias, rheumatic disease, acute regurgitation, and surgery in children and the elderly
Reviewing the latest invasive and non-invasive diagnostic techniques and analyzing the wide variety of management choices, Valvular Heart Disease
explicates the pathology, echocardiography, and the radiological examination of valvular diseases
discusses each of the heart valves
elucidates possible pitfalls in diagnosis and management
shows how to assess left and right ventricular function and how to time surgery
illustrates the benefits and drawbacks of medical, interventional, and surgical management, including balloon catheter, valvotomy, and valve repair
supplies an in-depth overview of conservative therapy
and more

The Role of Nutrition in Wound Healing (S.J. Dudrick). Chronic Wounds: Growth Factors and Comprehensive Surgical Care (D.R. Knighton). Wound Healing and Infection (D.E. Fry). The Plug Repair for Recurrent Inguinal Hernias (A.G. Shulman). Open Tensionfree Repair of Primary Inguinal Hernias in Adult Males (A.G. Shulman). Sepsis and Its Related Disorders: Definitions, Epidemiology, Pathogenesis and Pathophysiology (B.M. Friedman). The Septic Patient: Future Directions (T.J. Gallagher). Prophilaxis and Therapeutic Clinical Trials in Severe Sepsis and Septic Shock (G.J. Slotman). Pharmacologic Management of Postoperative Infections (J.D. Sutton). The Resuscitation Game (M.C. McCarthy). Transfusion Guidelines for Elective Surgery: The Transfusion Trigger (R.K. Spence). Physiologic Predictors of Transfusion Need in the Intensive Care Unit (L.D. Nelson). Preoperative Autologous Blood Donation (L.T. Goodnough). Component Therapy (K.F. O'Malley). The Anesthesiologist's Viewpoint: Transfusion, Hemodilution, and Cooperation (L. Stehling). Physicians' Assistants: An Overview (J.F. Byrnes, Jr.). Physicians Assistants: A Costefficient Solution for the Surgical Practice (L.A. Garry, D.L. Priore). Future 2000 for Nurses (Z.R. Wolf). Index.

Combining the approaches of preventative and restorative dentistry, this is a revised and updated guide to the clinical techniques and procedures necessary for managing tooth disorders and disease. * Introduces minimally invasive dentistry as a model to control dental disease and then restore the mouth to optimal form, function, and aesthetics * Contains several student-friendly features, including a new layout, line drawings and clinical photographs to illustrate key concepts * Covers fundamental topics, including the evolutionary biology of the human oral environment; caries management and risk assessment; remineralization; principles of cavity design; lifestyle factors; choices between restorative materials and restoration management * Includes a companion website with self-assessment exercises for students and a downloadable image bank for instructors

* Focuses on the technical aspects of surgery to ensure improved surgical technique * Easy to read, understand and apply the information * Fully illustrated with over 300 colour illustrations *Clear step-by-step techniques, to provide further insights into clinical practice*